Research line 1
- understand the interplay between diet, physical activity and clinical interventions on metabolic aberrations related to the metabolic syndrome
- examine how nutrition, physical activity and clinical interventions can have beneficial metabolic and functional effects
- understand and influence health/energy balance-related behaviours
- discover new evidence-based targets for the prevention and treatment of metabolic syndromes
Programmes research line 1
Programme 1: Energy balance and obesity
Intervention strategies for long-term maintenance of energy balance and food intake. Focuses on relations between dietary components, energy expenditure, physical activity and body composition. The number of studies on (neuro)endocrine mechanisms, brain signalling, and genetic predisposition is increasing. Also focuses on understanding and influencing health/energy balance-related behaviours in interaction with biological factors to develop interventions suitable for large-scale dissemination.
Programme 2: Diabetes and cardiovascular disease risk
Identifying and characterizing how nutrition, physical activity and clinical interventions can have beneficial molecular, metabolic and functional effects. Focuses on skeletal muscle, (brown) adipose tissue, blood vessels, the intestine, and increasingly the liver. Studies designed to gain insight into the relationships between diet, lipid and glucose metabolism and low-grade systemic inflammation. Knowledge obtained from studies under ‘normal’ conditions is applied to study and understand metabolic disturbances involved in aetiology of e.g. type 2 diabetes mellitus and cardiovascular disease.