Graduate School

School for Mental Health and Neuroscience

The School for Mental Health and Neuroscience (MHeNs) strives to advance our understanding of brain-behaviour relationships by using an approach integrating various disciplines in neuro- and behavioural science, medicine, and the life sciences. MHeNs performs high-impact neuroscience research and educates master's students and PhD researchers. MHeNs performs translational research, meaning practical collaboration between researchers in the lab and in the hospital .

Research

To perform research at every level, from the cellular to human, MHeNs is organised into three research lines:

  1. Cognitive Neuropsychiatry & Clinical Neuroscience – generates new insights into the neurocognitive and neurobehavioural mechanisms in order to improve treatment and care for people with cognitive disorders and other neurological disorders
  2. Mental Health – focusses on the mechanisms through which interactions between individuals and their environments contribute to the development of mental disorder and the impact of mental health services on morbidity
  3. Neuroscience – uncovers the underlying mechanisms of neurodegenerative and regenerative processes to improve health and to provide solutions to cure neurologic and neuropsychiatric disorders like Alzheimer's disease, Depression, Movement Disorders and Pain

Education

MHeNs is involved in the curricula of several international master's and research master's programmes of both the Faculty of Health, Medicine and Life Sciences and the Faculty of Psychology and Neuroscience. Internships for students are offered on a broad range of topics within the field of mental health and basic neuroscience. They are also offered independently of the master programme.

  • Rubicon Grants

    Rubicon grants for two UM researchers

    Friday, April 21, 2017

    Sandra Schipper and Mark van den Hurk, who both took their PhD in December 2016, received a Rubicon grant from research financing institution NWO. This grant gives young, highly promising researchers the opportunity to gain international research experience

    Read more
  • Explorer of the brain

    Tuesday, April 11, 2017
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    • Photo by MHeNs School for Mental Health and Neuroscience

      PhD Defense Dennis Oerlemans
      March 31, 2017: 10.00 hrs.
      Title: “Evolution of Neuromodulation for Lower Urinary Tract Dysfunction; Past, Present and Future”
      Promotores: Prof.dr. Ph. van Kerrebroeck; Prof.dr. G. van Koeveringe
      Co-promotores: Dr. E. Weil; Dr. T. Marcelissen

      1 month 2 weeks ago
    • Photo by MHeNs School for Mental Health and Neuroscience

      PhD Defense Claudia Vingerhoets
      March 23, 2017: 14.00 hrs.
      Title: “Investigating neurobiological mechanisms underlying comorbid cognitive symptoms in psychosis and substance use”
      Promotores: Prof.dr. T. van Amelsvoort; Prof.dr. J. Booij, UvA.
      Co-promotor: Dr. O. Bloemen

      1 month 2 weeks ago
    • Photo by MHeNs School for Mental Health and Neuroscience

      PhD Defense Rosalie van Knippenberg
      March 17, 2017: 14.00 hrs.
      Title: “Experience sampling in dementia care; an innovative intervention to support caregivers in daily life”
      Promotores: Prof.dr. F. Verhey; Prof.dr. R. Ponds; Prof.dr. I. Myin-Germeys, KU Leuven.
      Co-promotor: Dr. M. de Vugt

      1 month 2 weeks ago
    • Photo by MHeNs School for Mental Health and Neuroscience

      PhD Defense Daan Ophelders
      March 16, 2017: 10.00 hrs.
      Title: “Novel treatment strategies for the protection of the preterm brain; Re-balancing inflammation and regeneration”
      Promotor: Prof.dr. B. Kramer.
      Co-promotores: Dr. T. Wolfs; Dr. R. Jellema

      1 month 2 weeks ago
    • We would like to invite you for a lecture on Tuesday 14-03-2017 at 12.00 till 13.00, location: azM / 4th floor - Greepzaal.

      Lecture by: Ramona Hohnen
      Title: "Imaging of the local control system in the bladder wall’’

      Moderator: Suryan Dunker

      1 month 2 weeks ago
    • We would like to invite you for a lecture on Tuesday 21-02-2017 at 12.00 till 13.00, location: azM / 4th floor - Greepzaal.

      Lecture by: Wiep Scheper Dept. of Functional Genomics
      Dept. of Clinical Genetics and 3Alzheimer Center, VU University Medical Center, Amsterdam, The Netherlands

      Title:"THE UNFOLDED PROTEIN RESPONSE AND TAU PATHOLOGY’’

      Moderator : Pilar Martinez

      Abstract :
      THE UNFOLDED PROTEIN RESPONSE AND TAU PATHOLOGY

      Wiep Scheper

      Dept. of Functional Genomics, VU University, Amsterdam, The Netherlands
      Dept. of Clinical Genetics and 3Alzheimer Center, VU University Medical Center, Amsterdam, The Netherlands

      Activation of the unfolded protein response (UPR) is observed in close connection with early stages of tau pathology in Alzheimer’s disease (AD) and other tau-related neurodegenerative diseases. Tau pathology involves the phosphorylation and aggregation of the microtubule-binding protein tau. In addition, intercellular spreading of tau pathology is considered a key contributor to the progression of the disease from cell. Our lab investigates the connection between neuronal UPR (over)activation and the pathogenesis of tauopathies. We combine studies in post-mortem tissue, animal models and cell models to determine how the UPR is involved in cell autonomous and cell non-autonomous pathways in tau pathology.
      Our data demonstrate that activation of the UPR increases tau phosphorylation and aggregation in vitro. This appears to be mediated predominantly via the PERK pathway of the UPR. In addition our data suggest that seeded aggregation of tau is connected to UPR activation in vitro and in vivo.
      Our ultimate goal is to define the mechanistic connection between UPR signaling and tau pathology in order to identify targets for therapeutic intervention.

      2 months 1 week ago
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School for Mental Health and Neuroscience

Marie-Thérèse Moers