The Maastricht MultiModal Molecular Imaging Institute (M4I) is a state-of-the art molecular imaging institute that brings together a powerful palette of high-end, innovative imaging technologies. The mission of the institute is to perform fundamental, instrumentation and applied studies in molecular imaging as a part of a translational, synergistic, interdisciplinary research programme. M4I aims to be a leading international molecular imaging center relevant for science, education, economy and society. The institute aspires to generate a high-end research environment and a unique knowledge infrastructure, attractive to top researchers from all over the world.
M4I | Division of Nanoscopy
Strives for greater insight into the 3D form of cell proteins, paving the way for developing more effective treatments for diseases such as cancer and tuberculosis while gaining better understanding of how protein complexes manage healthy and diseased cells, allowing drugs and vaccines to work more effectively.
Go to division of Nanoscopy
M4I | Division of Imaging
Developing and applying state-of-the-art mass spectrometry based molecular imaging approaches for nanomedicine and biomedical research, including mass spectrometry as a diagnostic and prognostic tool for personalized medicine in oncology, neurology and cardiovascular medicine. Go to division of IMS
The M4I Division of Nanoscopy investigates cell structures at a macromolecular level. Inside cells, proteins work together in complex structures and are responsible for virtually all processes in the human body, including diseases such as cancer. To understand the working mechanisms of protein complexes, three-dimensional imaging of normal and disease-causing protein complexes is essential. This could ultimately lead to more effective treatments, but also to vaccines against diseases such as tuberculosis.
The M4I Division of Imaging Mass Spectrometry is one of the world leaders in high resolution molecular imaging of biological surfaces. The division targets the development and application of state-of-the-art mass spectrometry based molecular imaging approaches for biomedical cellular and tissue research. Main research aim for the coming years is to develop and apply mass spectrometry as a diagnostic and prognostic tool for personalized medicine.
Requests to access the Nanoscopy or Imaging Mass Spectrometry facilities of M4I can be specified using the 'Access to facilities'-contact form. The lab manager of the requested facility will evaluate your request.
Scientists from Maastricht University (UM) and researchers from Denmark and Germany have developed a new technique to accurately determine both the location and identity of lipids in bodily tissues in a single workflow. Lipids are essential molecules in every cell of our body and intimately involved in many important biological functions.
The Netherlands Organisation for Scientific Research (NWO) is allocating more than 17 million euros in subsidies for the further development of a Dutch network for electron microscopy (NEMI). Almost 5 million of this will go to UM. From Maastricht, the M4I institute of university professors Ron Heeren (mass spectrometry) and Peter Peters (cryo-electron microscopy) is one of the initiators of NEMI.
From November 13-17th, 2017 M4i organised its first workshop dedicated to Mass Spectrometry Imaging (MSI).
A new M4I office wing with the same open and transparent look and feel will be realised now. Based on C.O.R.E. collaborative open research education. C.O.R.E. requires a transparent and open environment for both laboratories and offices. M4I has invested heavily in an innovative and open environment for collaborative research. Research and office space is shared by scientist from very different backgrounds and disciplines, ranging from the fundamental sciences, technology and engineering as well as clinicians. In line with the CORE philosophy of Maastricht University the infrastructure is primed for researchers to cross the boundaries of their own disciplines and stimulate each other to excel in translational imaging science.