Publications

Mathew, A., Veloso, L. M. G. D. S., Giskes, F., Eijkel, G. B., Papanastasiou, D., Heck, A. J. R., Makarov, A. A., Ellis, S. R., & Heeren, R. M. A. (2026). Single-Ion Imaging Native Mass Spectrometry: Unraveling the Structural Features and Dissociation Energetics of Macromolecular Assemblies. Journal of the American Society for Mass Spectrometry, 37(7), 1641-1657. Article 37. https://doi.org/10.1021/jasms.6c00132

Flinders, B., van der Hulst, R., Heeren, R. M. A., & Cuypers, E. (2026). Spatiotemporal Mapping of Drug Incorporation in Human Nails by MALDI-FTICR-MSI. Journal of the American Society for Mass Spectrometry, 37(7), 1676-1682. Article 37. https://doi.org/10.1021/jasms.6c00151

Han, P., Thomassen, N., & Honing, M. (2026). A Combined MS/MS and IMS Study Into the Fragmentation Pathway of Nifedipine. Journal of Mass Spectrometry, 61(7), Article e70071. https://doi.org/10.1002/jms.70071

Hakke, S. S., Noteborn, W. E. M., Cabukusta, B., Gao, Y., Knoops, K., Lopez-Iglesias, C., Kilgour, D. P. A., Clarke, D. J., Mathew, A., & Heeren, R. M. A. (2026). Isotope Decluttering Reduces Spectral Complexity while Maintaining Protein Structure. Analytical Chemistry, 98(22), 16063-16072. https://doi.org/10.1021/acs.analchem.5c08046

Cao, B., Hadavi, D., Cillero-Pastor, B., & Honing, M. (2026). Application of surface plasmon resonance to elucidate the cooperative DNA binding mechanisms of NFATc1 and c-Jun. Biochimica et Biophysica Acta-general Subjects, 1870(6), Article 130924. https://doi.org/10.1016/j.bbagen.2026.130924

Koutrouli, M., Finotello, F., Schoof, E. M., Roussos, P., Theis, F. J., Marioni, J. C., Huber, W., Saka, S. K., Coscia, F., Mann, M., Cuypers, E., Puelles, V. G., Petrosius, V., Gaifas, L., Heeren, R. M. A., Hoffman, G. E., FNU, P., Rose, C. M., Leote, C., ... scverse Proteomics Consortium (2026). Unpaired data as a first-order challenge in single-cell and spatial proteomics. Nature Biotechnology, 44(6), 891-892. https://doi.org/10.1038/s41587-026-03074-8

Fedorova, M., Bendt, A. K., Bertrand-Michel, J., Fiehn, O., Godzien, J., Goracci, L., Gruber, F., Guan, X. L., Han, X., Holcapek, M., Kuligowski, J., Meikle, P. J., Nepachalovich, P., O'Donnell, V. B., Oresic, M., Penkov, S., Petrovic, S., Potapov, A., Prabutzki, P., ... Domingues, M. R. (2026). A lipidomics roadmap: from basic research to societal challenges. Nature Communications, 17(1), Article 4778. https://doi.org/10.1038/s41467-026-73797-4

Dost, A. F. M., Balazova, K., Pou Casellas, C., van Rooijen, L. M., Epskamp, W., van Son, G. J. F., van de Wetering, W. J., Lopez-Iglesias, C., Begthel, H., Peters, P. J., Smakman, N., van Es, J. H., & Clevers, H. (2026). Interferon-γ selectively promotes survival of alveolar progenitor cells in a human lung organoid model. The Embo Journal, 45(10), 3364-3395. https://doi.org/10.1038/s44318-026-00774-4

Iannone, M., Loomans, T., Gorremans, S., Grajchen, E., Deneubourg, C., Hrupka, B., Ver Donck, L., Bretteville, A., Moechars, D., Vreeken, R. J., & Jahouh, F. (2026). A sensitive LC-MS/MS method for the simultaneous quantification of hexosylceramides and hexosylsphingosines, their precursors and metabolites in cells, plasma, and tissue homogenates. Analytical and Bioanalytical Chemistry, 418(12), 3791-3806. https://doi.org/10.1007/s00216-026-06485-3

van Berlo, B., Esposito, P., Greco, A., van Assche, C. X. L., Bruyns, T., Van Asbroeck, B., Civati, C., Mohren, R., Cillero-Pastor, B., Guns, P.-J., De Keulenaer, G. W., & Segers, V. F. M. (2026). The role of angiotensin II in cardiovascular disease-induced cancer growth. Cardio-Oncology, 12(1), Article 79. https://doi.org/10.1186/s40959-026-00495-x

Krijnen, K., Bohm, S., Hohndorf, J., Heeren, R. M. A., & Anthony, I. G. M. (2026). Integrating Ion Beam Control into a Commercial Platform for Improved Multimodal SIMS/MALDI Imaging. Journal of the American Society for Mass Spectrometry, 37(4), 902-909. https://doi.org/10.1021/jasms.5c00423

Ponsaerts, L., Alders, L., Schepers, M., Kemps, H., Pirlet, E., Willems, E., De Bondt, M., Jacobs, R., Brullo, C., Bruno, O., Fedele, E., Ricciarelli, R., Prickaerts, J., Somers, V., Vandenbosch, M., Vanmierlo, T., & Bronckaers, A. (2026). Prophylactic PDE4 and PDE4B inhibition reduce lesion size and neutrophil infiltration following ischemic stroke in male mice. Journal of Cerebral Blood Flow and Metabolism, 46(4), 896-912. https://doi.org/10.1177/0271678X251386237

Nieste, N., Olde Damink, S. W. M., Heeren, R. M. A., Cuypers, E., & Bouwense, S. A. W. (2026). Mass spectrometry imaging in spatial biology of pancreatic cancer. Analyst, 151(7), 1861-1880. https://doi.org/10.1039/d5an01264c

Dey, S., Cao, J.-H., Balluff, B., Mazza, G., Ashwin, H., Gilbert, L., James, S., Dowle, A. A., Calder, G., Dey, N. S., O'Toole, P., Heeren, R. M. A., & Kaye, P. M. (2026). Ontogeny independent expression of LPCAT2 in granuloma macrophages during experimental visceral leishmaniasis. Communications Biology, 9(1), Article 641. https://doi.org/10.1038/s42003-026-09904-4

Kuligowski, J., Bertrand-Michel, J., Cazenave-Gassiot, A., Goracci, L., Domingues, P., Oresic, M., Thorsteinsdottir, M., Gruber, F., Willighagen, E. L., Spickett, C. M., Ruskovska, T., O'donnell, V. B., Prabutzki, P., Petrovic, S., Godzien, J., Tortorella, S., Reis, A., Dias, I. H. K., Schleyer, G., ... Fedorova, M. (2026). Outcomes and future activities of the 'Pan-European network in Lipidomics and EpiLipidomics - EpiLipidNET'. Metabolomics, 22(2), Article 42. https://doi.org/10.1007/s11306-026-02396-7

Kuik, C., Seccaroni, M., Freulings, K., Pressanto, M. C., Sforna, M., Bordoni, M., Calzoni, E., Emiliani, C., Pepe, M., Cillero-Pastor, B., & Chiaradia, E. (2026). Dysregulated Lipid and Protein Networks in Osteochondrosis. Journal of Proteome Research, 25(3), 1453-1464. https://doi.org/10.1021/acs.jproteome.5c00774

Hofstraat-Boersma, R., Marx, K., Blatnik, R., Claessen, N., Chojnacka, A., Peters-Sengers, H., Florquin, S., Kers, J., & Corthals, G. (2026). Highly Repeatable Tissue Proteomics for Kidney Transplant Pathology: Technical and Biological Validation of Protein Analysis Using Liquid Chromatography-Tandem Mass Spectrometry/Mass Spectrometry (LC-MS/MS). Laboratory Investigation, 106(3), Article 106073. https://doi.org/10.1016/j.labinv.2026.106073