Research institutes

M4I Division of Imaging Mass Spectrometry

Developing and applying state-of-the-art mass spectrometry based molecular imaging approaches for nanomedicine and biomedical research, including mass spectrometry as a diagnostic and prognostic tool for personalized medicine in oncology, neurology and cardiovascular medicine.


  • LINK logo

    Extra research groups to strengthen top institutes MERLN and M4i

    Wednesday, April 13, 2022

    DThe multimillion-euro investment in the LINK programme by the Province of Limburg, Maastricht University (UM) and Maastricht UMC+ (MUMC+) has achieved its targets. And the LINK programme is to have a sequel: UM and MUMC+ will be investing eight million euros in MERLN and M4i in the coming years to give an extra boost to regenerative medicine and imaging. 

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    “From Atoms to Cells, Nanobiology course leads to wonderful illustrations” Raimond Ravelli

    Tuesday, October 19, 2021
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  • amandaeva.jpg

    Amanda Hummon on a mission: personalized treatment for cancer patients

    Monday, October 18, 2021
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  • M4i Transparent

    World-renowned Mass Spectrometry conference to be held in Maastricht in 2022

    Tuesday, June 1, 2021

    This biennial conference focuses on the breadth of mass spectrometry. 

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  • M4i Transparent logo

    Role of immune metabolism in a mouse model of Non Alcoholic SteatoHepatitis (NASH)

    Monday, March 29, 2021

    Auto-aggressive CXCR6+ CD8 T cells cause liver immune pathology in NASH.

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  • M4i Transparent logo

    Dr. Berta Cillero-Pastor and Prof. Ron Heeren receive again ITN grant

    Tuesday, March 23, 2021

    ITN grant for M4i FoodTraNet project: Advanced Research and Training Network in food quality, safety and security.

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  • M4i Transparent

    Direct detection of sarcomen during an operation with an i-knife

    Wednesday, March 10, 2021 Read more
  • M4I

    M4i researchers Dr. Berta Cillero Pastor and Prof. Maarten Honing participate in DARTBAC project

    Wednesday, December 2, 2020

    Developing new mass spectrometry (imaging) and SPR based solutions.

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  • web logo M4I

    M4I researcher receives funding from Michael J Fox Foundation

    Monday, November 16, 2020

    The project builds on several technical developments made at M4I in the fields of mass spectrometry imaging (MSI) and lipid analysis.

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  • Microscopic image of coronavirus

    UM students dive into COVID-19 at the nano level

    Tuesday, October 13, 2020 Read more


The M4I Division of Imaging Mass Spectrometry is one of the world leaders in high resolution molecular imaging of biological surfaces. The division targets the development and application of state-of-the-art mass spectrometry based molecular imaging approaches for biomedical cellular and tissue research. Main research aim for the coming years is to develop and apply mass spectrometry as a diagnostic and prognostic tool for personalized medicine.


M4I’s scientists will be involved in teaching at a bachelor's, master's and PhD level, within the University College Maastricht, the Maastricht Science Programme and various programmes within the Faculty of Health, Medicine and Life Sciences and the Faculty of Science and Engineering.

The M4I imaging MS laboratories  - a virtual tour
Join Prof. Ron M.A. Heeren for a virtual guided tour through the imaging mass spectrometry laboratories of M4I. You wil get some insights in the breadth of high end, mass spectrometry based molecular imaging infrastructure in the labs.

Perhaps a place where you would like to an internship or pursue a career in molecular imaging!

If you are interested, please send your cv and motivation letter to h.schott[at]maastrichtuniversity[dot]nl

Visiting address: M4I Division of Imaging Mass Spectrometry

Prof Ron Heeren - contact Helen Schott