Cancer and Molecular Epidemiology

The research area Cancer & Molecular Epidemiology aims to study determinants of cancer development and progression and of the prognosis, quality of life, and preservation of functioning after a cancer diagnosis (cancer survivorship). The research area focuses on several types of cancer, including colorectal, kidney, and breast cancer. Lifestyle and related factors are main determinants of interest, including diet, physical activity, and body composition. In addition, genetic and other molecular biomarkers are studied, including research on tumor heterogeneity and subtyping based on molecular markers. Patient-oriented clinical studies on cancer screening and prognosis are also part of the research area, focusing mostly on early detection strategies and treatment modalities for breast cancer

The research area Cancer & Molecular Epidemiology includes three main research themes:

  1. Cancer etiology & prognosis
  2. Cancer survivorship
  3. Clinical epidemiology of breast cancer

The research serves as a knowledge base for improving primary, secondary, and tertiary cancer prevention strategies. Findings are translated into cancer prevention guidelines and lifestyle recommendations and used as input for developing interventions for cancer survivors and for improving cancer screening programs.

Themes

Cancer Etiology and Prognosis

Cancer Etiology & Prognosis

Observational research on determinants and underlying mechanisms contributing to the development and progression of several types of cancer.

Cancer Survivorship

Cancer Survivorship

Observational research on determinants of improved quality of life, preservation of function, and prognosis after a cancer diagnosis and treatment.

Clinical Epidemiology of Breast Cancer

Clinical Epidemiology of Breast Cancer

Clinical epidemiological research focused on improving diagnosis, treatment, and prognosis of breast cancer.

Cohorts

NLCS Study

Netherlands Cohort Study on Diet and Cancer

Prospective cohort study on role of lifestyle in cancer etiology and prognosis, including molecular and genetic mechanisms.

Encore Study

EnCoRe study

Prospective cohort study on role of lifestyle on quality of life, functioning, adverse treatment effects, and prognosis in colorectal cancer survivors.