Doctoral theses - Research - Maastricht University

2022

Mind The Gatekeeper: Key role of NPC1 protein and lysosomal cholesterol in metabolic diseases and therapeutical implications

Inês Andreia Gonçalves Magro dos Reis, 26.01.2022

Mind The Gatekeeper: Key role of NPC1 protein and lysosomal cholesterol in metabolic diseases and therapeutical implications

26.01.2022
Promotor: Prof. dr. Ronit Shiri-Sverdlov
Co-promotor: Dr. Tom Houben

Thesis Inês Andreia Gonçalves Magro dos Reis

Mind The Gatekeeper: Key role of NPC1 protein and lysosomal cholesterol in metabolic diseases and therapeutical implications
Inês Andreia Gonçalves Magro dos Reis, 26.01.2022

2021

Friends, enemies and everything in between: vaginal microbiota and sexually transmitted infections among sub-Saharan African pregnant women

Naomi Juliana, 07.01.2021

Friends, enemies and everything in between: vaginal microbiota and sexually transmitted infections among sub-Saharan African pregnant women

7 January 2021
Promotor: prof.dr. S.A. Morré
Co-promotor: dr. E. Ambrosino

Doctoral Thesis Juliana Naomi

The entanglement of plasma Cathepsin D and metabolic disturbances: relevant insights in the metabolic syndrome

Lingling Ding, 18.05.2021

The entanglement of plasma Cathepsin D and metabolic disturbances: relevant insights in the metabolic syndrome

18 May 2021
Supervisor: prof.dr. R. Sverdlov
Co-supervisor: dr. T. Houben

Doctoral Thesis Lingling Ding

Small molecules, big consequences: Novel therapeutic approaches for treating chronic inflammatory diseases

Tulasi Yadati, 18.11.2021

Small molecules, big consequences: Novel therapeutic approaches for treating chronic inflammatory diseases

18 November 2021
Supervisor: Prof. dr. Ronit Shiri-Sverdlov
Co-supervisor: Dr. Tom Houben

Doctoral Thesis Tulasi Yadati

PhD Defences of Genetics and Cell Biology

2020

Metabolic phenotyping of the pressure-overloaded Heart – Focus on model development

Ilvy Geraets, 24.01.2020

Metabolic phenotyping of the pressure-overloaded Heart – Focus on model development

24 January 2020
Promotor: prof.dr. J.F.C. Glatz
Co-promotores: dr. M. Nabben; dr. J.J.F.P. Luiken

Doctoral Thesis Ilvy Geraets

Conceptualisations of successful ageing and leads for lifestyle modification

Sarah Mount, 30.01.2020

Conceptualisations of successful ageing and leads for lifestyle modification

30 January 2020
Supervisors: prof.dr. A.M.W.J. Schols; prof.dr. M.P.A. Zeegers
Co-supervisor: dr. A. Wesselius

Doctoral Thesis Sarah Mount

Diet and bladder cancer risk and recurrence

Sylvia Jochems, 13.02.2020

Diet and bladder cancer risk and recurrence

13 February 2020
Promotores: prof.dr. M.P. Zeegers; prof.dr. F.J. v. Schooten
Co-promotor: dr. A. Wesselius
Double doctoral degree Maastricht University-University of Birmingham

Big Data and Prevention of Bladder Cance

Yiwen Yu, 07.07.2020

Big Data and Prevention of Bladder Cance

7 July 2020
Supervisor: prof.dr. M.P.A. Zeegers
Co-supervisors: dr. A. Wesselius, dr. S. Mehrkanoon

Doctoral Thesis Yiwen Yu

Role for phosphatidylinositol 4-kinase IIIβ in cardiac metabolic diseases

Aomin Sun, 08.09.2020

Role for phosphatidylinositol 4-kinase IIIβ in cardiac metabolic diseases

8 September 2020
Promomtor: prof. dr. J.F.C. Glatz
Co-promotores: dr. J.J.F.P. Luiken, dr. D. Neumann

Doctoral Thesis Aomin Sun

Vacuolar H+-ATPase as target to restore cardiac function in the diabetic heart

Shujin Wang, 08.09.2020

Vacuolar H+-ATPase as target to restore cardiac function in the diabetic heart

8 September 2020
Supervisor: prof. dr. J.F.C. Glatz
Co-supervisors: dr. J.J.F.P. Luiken, dr. M. Nabben

Doctoral Thesis Shujin Wang

Inconspicuous offender: Pathophysiological role of Oxidized-Low Density Lipoprotein in metabolic disease

Albert Bitorina, 29.09.2020

Inconspicuous offender: Pathophysiological role of Oxidized-Low Density Lipoprotein in metabolic disease

29 September 2020
Promotor: prof. dr. R. Sverdlov
Co-promotor: dr. J. Theys

Doctoral Thesis Albert Bitorina

Classic galactosemia: natural history and new treatment approaches

Minela Hasković, 02.10.2020

Classic galactosemia: natural history and new treatment approaches

2 October 2020
Promotores: prof.dr. M.E. Rubio-Gozalbo, prof.dr. L.J. Zimmermann
Co-promotor: dr. A. Cruz Coelho

Doctoral Thesis Minela Hasković

Germline Prognostic Markers For Urinary Bladder Cancer

Nadežda Lipunova, 12.11.2020

Germline Prognostic Markers For Urinary Bladder Cancer

12 November 2020
Supervisors: prof.dr. M.P. Zeegers, prof.dr. F.J. van Schooten
Co-supervisor: dr. A. Wesselius

Doctoral Thesis Nadežda Lipunova

A reproductive dilemma? Optimizing counselling for couples with hereditary breast and ovarian cancer who consider using preimplantation genetic diagnosis

Joyce J.G. Gietel-Habets, 10.12.2020

A reproductive dilemma? Optimizing counselling for couples with hereditary breast and ovarian cancer who consider using preimplantation genetic diagnosis

10 December 2020
Promotores: prof. dr. C.E.M. de Die-Smulders, prof. dr. V.C.G. Tjan-Heijnen
Co-promotor: dr. L.A.D.M. van Osch

Doctoral Thesis Joyce Gietel-Habets

PhD Defences of Genetics and Cell Biology

2019

Neurodevelopmental disorders: a next generation

Margot Reijnders, 11.01.2019

Neurodevelopmental disorders: a next generation

11 January 2019
Supervisors: prof. H. Brunner, T. Kleefstra, PhD, L. Vissers, PhD

Doctoral Thesis Margot Reijnders

A zebrafish model of small-fiber neuropathy

Ivo Eijkenboom, 22.02.2019

A zebrafish model of small-fiber neuropathy

22 February 2019
Supervisors: prof. H.J.M.Smeets, prof. C.G. Faber
Co-supervisor: J. Vanoevelen, PhD

Reproductive decision support in hereditary cancer. The development and evaluation of an online decision aid

Kelly Reumkens, 28.03.2019

Reproductive decision support in hereditary cancer. The development and evaluation of an online decision aid

28 March 2019
Supervisor: prof. C.E.M. de Die-Smulders
Co-supervisor: L.A.D.M. van Osch, PhD

Doctoral Thesis Kelly Reumkens

Smoking and bladder cancer risk and recurrence

Frits van Osch, 12.04.2019

Smoking and bladder cancer risk and recurrence

12 April 2019
Supervisors: Prof. M. Zeegers, F.J. van Schooten, PhD, R. Bryan, PhD
Co-supervisor: A. Wesselius, PhD

Doctoral Thesis Frits van Osch

Standing on one shoulder, citation bias in the epidemiological literature

Bram Duyx, 17.04.2019

Standing on one shoulder, citation bias in the epidemiological literature

17 April 2019
Supervisors: Prof. M. Zeegers, Prof. L. Bouter
Co-supervisor: G. Swaen, PhD

Doctoral Thesis Bram Duyx

Selective citation and its consequences

Miriam Urlings, 03.07.2019

Selective citation and its consequences

3 July 2019
Supervisors: Prof. M. Zeegers, Prof. L. Bouter
Co-supervisor: G. Swaen, PhD

Doctoral Thesis Miriam Urlings

PhD Defences of Genetics and Cell Biology

2018

Clinical evaluation of preimplantation genetic diagnosis for BRCA1/2 mutations

Inge Derks-Smeets, 17.01.2018

Clinical evaluation of preimplantation genetic diagnosis for BRCA1/2 mutations

17 January 2018
Supervisors: prof. C. de Die-Smulders, prof. V. Tjan-Heijnen,
prof. W. Verpoest (VUB, België)
Co-supervisor: R. van Golde, PhD

Doctoral Thesis Inge Derks

Lysosomes ‘in control’: where lipids meet inflammation in metabolic syndrome

Tom Houben, 18.01.2018

Lysosomes ‘in control’: where lipids meet inflammation in metabolic syndrome

18 January 2018
Supervisors: prof. dr. Ronit Shiri-Sverdlov, prof. dr. Marten Hofker †

Doctoral Thesis Tom Houben

Prenatal Exposure to Polyunsaturated Fatty Acids and Child Health: a Population-Based Approach

Nikos Stratakis, 02.03.2018

Prenatal Exposure to Polyunsaturated Fatty Acids and Child Health: a Population-Based Approach

2 March 2018
Supervisors: prof. M. Zeegers, prof. R. de Groot
Co-supervisor: L. Chatzi, PhD, M. Gielen, PhD

Doctoral Thesis Nikos Stratakis

Novel causes, mechanisms and therapeutic strategies in mitochondrial disease

Tom Theunissen, 18.04.2018

Novel causes, mechanisms and therapeutic strategies in mitochondrial disease

18 April 2018
Supervisor: prof. H.J.M. Smeets
Co-supervisors: R. Szklarczyk, PhD, I.F.M. de Coo, PhD (Erasmus MC)

Doctoral Thesis Tom Theunissen

Detection and immunogenetics of sexually transmitted infections

Dewi de Waaij, 09.05.2018

Detection and immunogenetics of sexually transmitted infections

9 May 2018
Supervisors: prof. S.A. Morré, prof. R. Peters, S. Ouburg, PhD (VUmc)

Preventive genetic testing. Our best foot forward

Kelly Stewart, 20.09.2018

Preventive genetic testing. Our best foot forward

20 September 2018
Supervisors: prof. M. Zeegers, prof. A. Schols
Co-supervisor: A. Wesselius, PhD

Doctoral Thesis Kelly Stewart

Challenges and targeted opportunities for integrating innovation into Europe's Healthcare Systems

Denis A. Horgan, 16.11.2018

Challenges and targeted opportunities for integrating innovation into Europe's Healthcare Systems

16 November 2018
Supervisors: prof. S. Morré
Co-supervisor: H.J. van Kranen, PhD

ChlamIndia: burden of Chlamydia trachomatis in India, implications for policy and practice

Pierre P.M. Thomas, 14.12.2018

ChlamIndia: burden of Chlamydia trachomatis in India, implications for policy and practice

14 December 2018
Supervisors: prof. S.A. Morré and prof. J.A. Lal (SHUATS Allahabad, Uttar Pradesh, India)
Co-supervisor: E. Ambrosino, PhD

Growth hormone therapy in kabuki syndrome

Nina A. Schott, 20.12.2020

Growth hormone therapy in kabuki syndrome

20 December 2018
Supervisors: prof. C.T.R.M. Stumpel, prof. L.J.I. Zimmermann
Co-supervisor: W.J.M. Gerver, PhD

Doctoral Thesis Nina A. Schott