Research institutes

Maastricht MultiModal Molecular Imaging Institute

The Maastricht MultiModal Molecular Imaging Institute (M4I) is a state-of-the art molecular imaging institute that brings together a powerful palette of high-end, innovative imaging technologies. The mission of the institute is to perform fundamental, instrumentation and applied studies in molecular imaging as a part of a translational, synergistic, interdisciplinary research programme. M4I aims to be a leading international molecular imaging center relevant for science, education, economy and society.  The institute aspires to generate a high-end research environment and a unique knowledge infrastructure, attractive to top researchers from all over the world.

A Brightlands institute

Brightlands logo

Brightlands is an open innovation community in a global context, connecting four campuses in the province of Limburg: in Maastricht, Heerlen, Sittard-Geleen and Venlo. The campuses provide entrepreneurs, scientists and students state-of-the-art facilities to support development, education, innovation and growth. Naturally, there are close links between all four Brightlands campuses, and together they enable Limburg to serve as an innovation region where researchers and entrepreneurs take on the major challenges in the areas of materials, health, food and smart services.

5 Years M4i: Images, Impact, Innovation

5 Years M4i lustrum book

IMAGES are at the heart of our activities. On a daily basis we are now producing Terabytes of imaging information of molecules, cells and tissues.

It is sometimes easy to forget that at the end of 2019, it was only 5 years ago that this incredible Maastricht adventure started. With the help of many, we were able to build M4i in record time and establish a unique ecosystem that is now part of the Dutch large-scale scientific infrastructure.

This lustrum book reflects on the first five years of the institute, the people and organizations that have contributed to our success.

Click here to download the pdf of the M4i Lustrum Book.

Two M4I Divisions

1 - M4I | Division of Nanoscopy
Strives for greater insight into the 3D form of cell proteins, paving the way for developing more effective treatments for diseases such as cancer and tuberculosis while gaining better understanding of how protein complexes manage healthy and diseased cells, allowing drugs and vaccines to work more effectively.
 Go to division of Nanoscopy

2 - M4I | Division of Imaging
Mass Spectrometry

Developing and applying state-of-the-art mass spectrometry based molecular imaging approaches for nanomedicine and biomedical research, including mass spectrometry as a diagnostic and prognostic tool for personalized medicine in oncology, neurology and cardiovascular medicine.  Go to division of IMS

Access to facilities

Requests to access the Nanoscopy or Imaging Mass Spectrometry facilities of M4I can be specified using the 'Access to facilities'-contact form. The lab manager of the requested facility will evaluate your request.


  • M4i Transparent

    World-renowned Mass Spectrometry conference to be held in Maastricht in 2022

    Tuesday, June 1, 2021

    This biennial conference focuses on the breadth of mass spectrometry. 

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  • M4i Transparent logo

    Role of immune metabolism in a mouse model of Non Alcoholic SteatoHepatitis (NASH)

    Monday, March 29, 2021

    Auto-aggressive CXCR6+ CD8 T cells cause liver immune pathology in NASH.

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  • M4i Transparent logo

    Dr. Berta Cillero-Pastor and Prof. Ron Heeren receive again ITN grant

    Tuesday, March 23, 2021

    ITN grant for M4i FoodTraNet project: Advanced Research and Training Network in food quality, safety and security.

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  • M4i Transparent

    Direct detection of sarcomen during an operation with an i-knife

    Wednesday, March 10, 2021 Read more
  • M4I

    M4i researchers Dr. Berta Cillero Pastor and Prof. Maarten Honing participate in DARTBAC project

    Wednesday, December 2, 2020

    Developing new mass spectrometry (imaging) and SPR based solutions.

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  • web logo M4I

    M4I researcher receives funding from Michael J Fox Foundation

    Monday, November 16, 2020

    The project builds on several technical developments made at M4I in the fields of mass spectrometry imaging (MSI) and lipid analysis.

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  • Microscopic image of coronavirus

    UM students dive into COVID-19 at the nano level

    Tuesday, October 13, 2020 Read more
  • M4i’s Darya Hadavi wins ISIMS competition

    M4i’s Darya Hadavi wins ISIMS competition

    Friday, August 14, 2020

    M4i’s PhD candidate Darya Hadavi has won the best poster prize at the International Society for Ion Mobility Spectrometry (ISIMS) Poster Symposium 2020.

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  • Cancer cells

    IMS CORE lab teams up with Cristal Therapeutics

    Monday, July 6, 2020

    The ICARUS project will be carried out in close collaboration with the IMS CORE lab at the M4I division of Imaging Mass Spectrometry, ​where CriPec® nanoparticle microlocalisation and drug release in tumours will be evaluated.

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  • Peter Peters corana image

    How the coronavirus infects our small intestines

    Monday, May 18, 2020

    Interview with prof. Peter Peters on the Science article he co-worked on intensively.

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