Research institutes

Maastricht MultiModal Molecular Imaging Institute

The Maastricht MultiModal Molecular Imaging Institute (M4I) is a state-of-the art molecular imaging institute that brings together a powerful palette of high-end, innovative imaging technologies. The mission of the institute is to perform fundamental, instrumentation and applied studies in molecular imaging as a part of a translational, synergistic, interdisciplinary research programme. M4I aims to be a leading international molecular imaging center relevant for science, education, economy and society.  The institute aspires to generate a high-end research environment and a unique knowledge infrastructure, attractive to top researchers from all over the world.

A Brightlands institute

Brightlands logo

Brightlands is an open innovation community in a global context, connecting four campuses in the province of Limburg: in Maastricht, Heerlen, Sittard-Geleen and Venlo. The campuses provide entrepreneurs, scientists and students state-of-the-art facilities to support development, education, innovation and growth. Naturally, there are close links between all four Brightlands campuses, and together they enable Limburg to serve as an innovation region where researchers and entrepreneurs take on the major challenges in the areas of materials, health, food and smart services.

5 Years M4i: Images, Impact, Innovation

5 Years M4i lustrum book

IMAGES are at the heart of our activities. On a daily basis we are now producing Terabytes of imaging information of molecules, cells and tissues.

It is sometimes easy to forget that at the end of 2019, it was only 5 years ago that this incredible Maastricht adventure started. With the help of many, we were able to build M4i in record time and establish a unique ecosystem that is now part of the Dutch large-scale scientific infrastructure.

This lustrum book reflects on the first five years of the institute, the people and organizations that have contributed to our success.

Click here to download the pdf of the M4i Lustrum Book.

Two M4I Divisions

1 - M4I | Division of Nanoscopy
Strives for greater insight into the 3D form of cell proteins, paving the way for developing more effective treatments for diseases such as cancer and tuberculosis while gaining better understanding of how protein complexes manage healthy and diseased cells, allowing drugs and vaccines to work more effectively.
 Go to division of Nanoscopy

2 - M4I | Division of Imaging
Mass Spectrometry

Developing and applying state-of-the-art mass spectrometry based molecular imaging approaches for nanomedicine and biomedical research, including mass spectrometry as a diagnostic and prognostic tool for personalized medicine in oncology, neurology and cardiovascular medicine.  Go to division of IMS

Access to facilities

Requests to access the Nanoscopy or Imaging Mass Spectrometry facilities of M4I can be specified using the 'Access to facilities'-contact form. The lab manager of the requested facility will evaluate your request.


  • Cancer cells

    IMS CORE lab teams up with Cristal Therapeutics

    Monday, July 6, 2020

    The ICARUS project will be carried out in close collaboration with the IMS CORE lab at the M4I division of Imaging Mass Spectrometry, ​where CriPec® nanoparticle microlocalisation and drug release in tumours will be evaluated.

    Read more
  • Peter Peters corana image

    How the coronavirus infects our small intestines

    Monday, May 18, 2020

    Interview with prof. Peter Peters on the Science article he co-worked on intensively.

    Read more
  • corona virus

    Coronavirus SARS-CoV-2 infects cells of the intestine

    Friday, May 1, 2020

    Researchers from the Hubrecht Institute in Utrecht, Erasmus MC University Medical Center Rotterdam, and Maastricht University in the Netherlands have found that the coronavirus SARS-CoV-2, which causes COVID-19, can infect cells of the intestine and multiply there.

    Read more
  • Prof. Maarten Honing joins Dutch Chemistry Council

    Monday, March 2, 2020 Read more
  • Logo M4I

    Realising hair’s information richness

    Tuesday, January 21, 2020

    Interview with Cyrille Depondt, director of Dutch Screening Group (DSG), a spin-off company that originated from Ron Heeren's research.

    Read more
  • Logo M4I

    ASI: From science to business

    Monday, January 13, 2020

    Interview with Hans Brouwer, CEO of Amsterdam Scientific Instruments, a spin-off company that originated from professor Ron Heeren's knowledge development.

    Read more
  • Ron Heeren

    "Research serves a higher purpose"

    Monday, November 18, 2019

    Interview with prof. Ron Heeren because of his winning the NWO Physics Valorisation Prize.

    Read more
  • NWO Physics Valorisation Prize for UM Professor Ron Heeren

    Monday, November 18, 2019

    This year, the prize for the best knowledge utilisation in physics goes to Ron Heeren (M4I). He works on improving clinical diagnostics by means of mass spectrometry imaging.

    Read more
  • Ron Heeren on Power List

    Ron Heeren included on Power List of Top Analytical Scientists

    Monday, October 28, 2019

    UM professor of Molecular Imaging Ron Heeren has been named to The Analytical Scientist's 2019 Power List.

    Read more
  • vitrojet

    Technical feats at 180 degrees below zero

    Thursday, April 4, 2019

    Frank Nijpels is working on the Vitrojet, a new device that prepares samples for a form of electron microscopy that received the 2017 Nobel Prize in Chemistry.

    Read more