Graduate School

School for Mental Health and Neuroscience

The School for Mental Health and Neuroscience (MHeNs) strives to advance our understanding of brain-behaviour relationships by using an approach integrating various disciplines in neuro- and behavioural science, medicine, and the life sciences. MHeNs performs high-impact neuroscience research and educates master's students and PhD researchers. MHeNs performs translational research, meaning practical collaboration between researchers in the lab and in the hospital .

Research

To perform research at every level, from the cellular to human, MHeNs is organised into three research lines:

  1. Cognitive Neuropsychiatry & Clinical Neuroscience – generates new insights into the neurocognitive and neurobehavioural mechanisms in order to improve treatment and care for people with cognitive disorders and other neurological disorders
  2. Mental Health – focusses on the mechanisms through which interactions between individuals and their environments contribute to the development of mental disorder and the impact of mental health services on morbidity
  3. Neuroscience – uncovers the underlying mechanisms of neurodegenerative and regenerative processes to improve health and to provide solutions to cure neurologic and neuropsychiatric disorders like Alzheimer's disease, Depression, Movement Disorders and Pain

Education

MHeNs is involved in the curricula of several international master's and research master's programmes of both the Faculty of Health, Medicine and Life Sciences and the Faculty of Psychology and Neuroscience. Internships for students are offered on a broad range of topics within the field of mental health and basic neuroscience. They are also offered independently of the master programme.

    • We would like to invite you for a lecture on Tuesday 21-02-2017 at 12.00 till 13.00, location: azM / 4th floor - Greepzaal.

      Lecture by: Wiep Scheper Dept. of Functional Genomics
      Dept. of Clinical Genetics and 3Alzheimer Center, VU University Medical Center, Amsterdam, The Netherlands

      Title:"THE UNFOLDED PROTEIN RESPONSE AND TAU PATHOLOGY’’

      Moderator : Pilar Martinez

      Abstract :
      THE UNFOLDED PROTEIN RESPONSE AND TAU PATHOLOGY

      Wiep Scheper

      Dept. of Functional Genomics, VU University, Amsterdam, The Netherlands
      Dept. of Clinical Genetics and 3Alzheimer Center, VU University Medical Center, Amsterdam, The Netherlands

      Activation of the unfolded protein response (UPR) is observed in close connection with early stages of tau pathology in Alzheimer’s disease (AD) and other tau-related neurodegenerative diseases. Tau pathology involves the phosphorylation and aggregation of the microtubule-binding protein tau. In addition, intercellular spreading of tau pathology is considered a key contributor to the progression of the disease from cell. Our lab investigates the connection between neuronal UPR (over)activation and the pathogenesis of tauopathies. We combine studies in post-mortem tissue, animal models and cell models to determine how the UPR is involved in cell autonomous and cell non-autonomous pathways in tau pathology.
      Our data demonstrate that activation of the UPR increases tau phosphorylation and aggregation in vitro. This appears to be mediated predominantly via the PERK pathway of the UPR. In addition our data suggest that seeded aggregation of tau is connected to UPR activation in vitro and in vivo.
      Our ultimate goal is to define the mechanistic connection between UPR signaling and tau pathology in order to identify targets for therapeutic intervention.

      1 week 4 days ago
    • Lorentz Workshop Life Sciences with Industry
      April 3-7, 2017
      Leiden, The Netherlands

      Lorentz Workshop Life Sciences with Industry | MHeNS School for Mental Health and Neuroscience
      1 week 6 days ago
    • Photo by MHeNs School for Mental Health and Neuroscience

      MHeNs School for Mental Health and Neuroscience shared their photo.

      2 weeks 15 hours ago
    • Dear all,

      We would like to invite you for a lecture on Tuesday 14-02-2017 at 12.00 till 13.00, location: azM / 4th floor - Greepzaal.

      Lecture by: Sandra Schipper
      Title: "Neuro-urology -current investigation and future perspective'’

      Moderator : Prof.dr. Marc De Baets

      2 weeks 1 day ago
    • Photo by MHeNs School for Mental Health and Neuroscience

      OPEN DAG | LABORATORIA NEUROSCIENCE | 24 maart 2017

      De onderzoekers van de divisie Neuroscience van de School for Mental Health and Neuroscience doen zeer geavanceerd onderzoek om de onderliggende mechanismes te begrijpen van neurologische en psychiatrische afwijkingen, zoals dementie, de ziekte van Parkinson, epilepsie, psychose en andere.

      Deze open dag in de laboratoria van de divisie Neurosicence is voor iedereen die interesse heeft in Neuroscience.

      De dag zal bestaan uit een welkomstwoord en introductie door het hoofd van de divisie, rondleidingen door de laboratoria van Neurosciene met aandacht voor de expertise op neuroanatomisch, neurobiologisch en neuropsycho logische technieken alsmede de mogelijkheid van het stellen van vragen aan voorname neuro-onderzoekers.

      Wij hopen dat u in de gelegenheid bent om onze open dag te bezoeken zodat u een goede indruk krijgt van de wetenschappelijke studies die binnen Neuroscience worden gedaan, uitgevoerd bij de Universiteit in Maastricht.
      Voor meer informatie: https://mhens.mumc.maastrichtuniversity.nl/neuroscience

      Gelieve in te schrijven vóór 1 maart aanstaande via secr-neuroscience[at]maastrichtuniversity[dot]nl

      3 weeks 1 day ago
    • Dear all,

      We would like to invite you for a lecture on Tuesday 07-02-2017 at 12.00 till 13.00, location: azM / 4th floor - Greepzaal.

      Lecture by: Prof.dr. Marc De Baets
      Title: "Immunotherapy of neurodegenerative diseases’’

      3 weeks 1 day ago
    • Photo by MHeNs School for Mental Health and Neuroscience

      PhD Defense Martin M. Müller
      February 24, 2017: 12.00 hrs.
      Title: “Pregnancy derived products for treatment of perinatal brain injuries”
      Promotores: Prof.dr. B.W.W. Kramer; Prof.dr. D. Surbek, Bern
      Co-promotores: Dr. T. Wolfs; Dr. G. Gavilanes

      3 weeks 6 days ago
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School for Mental Health and Neuroscience

Marie-Thérèse Moers