PhD conferral Vincent Meyer
Supervisor: Prof. dr. G.L. Beets
Co-supervisors: Dr. H.L. van Westreenen (Isala Ziekenhuis Zwolle), Dr. W.H. de Vos tot Nederveen Cappel (Isala Ziekenhuis Zwolle)
Keywords: rectal cancer, Watch and Wait, quality of life, survey research
"Outcome assessment of developments in rectal cancer
treatment: a patient and surgical perspective"
Locally advanced rectal cancer is treated with chemotherapy, radiotherapy and surgery. A minority of patients (25%) have such a good response to chemo and radiotherapy, that surgery can be omitted. This is called Watch and Wait. These patients do not have to bear the significant problems that come with major abdominal surgery. This thesis investigates the outcomes of patients that ‘fail’ Watch and Wait because the tumor returns and still need surgery; regarding complications, development of the cancer and quality of life. Additionally, this thesis explores whether in this case a much more limited operation is feasible. Finally, factors that influence response to questionnaire studies are examined as these studies form the backbone of patient reported outcomes we rely upon.
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"The Radiological Report: A compromise between Structured Reporting and Natural Language Processing"
"Getting in control: Towards optimal self-management support for chronically ill patients with limited health literacy"
"Human cardiometabolic health The role of genetic variants, diurnal rhythms, and intermittent energy restriction diets"