Dr V. Melotte
Recent publications
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Tasnády, K. R., Jehoul, R., de Ravé, M. G., Gijbels, M. J., Brône, B., Dewachter, I., Melotte, V., & Boesmans, W. (2025). Gastrointestinal Dysfunction and Low-Grade Inflammation Associate With Enteric Neuronal Amyloid-β in a Model for Amyloid Pathology. Neurogastroenterology and Motility, 37(5), Article e15016. Advance online publication. https://doi.org/10.1111/nmo.15016More information about this publication
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Windster, J. D., Kakiailatu, N. J. M., Kuil, L. E., Antanaviciute, A., Sacchetti, A., MacKenzie, K. C., Peulen-Zink, J., Kan, T. W., Bindels, E., de Pater, E., Doukas, M., van den Bosch, T. P. P., Yousefi, S., Barakat, T. S., Meeussen, C., Sloots, C. E. J., Wijnen, R. M. H., Parikh, K., Boesmans, W., ... Alves, M. M. (2025). Human enteric glia diversity in health and disease: new avenues for the treatment of Hirschsprung disease. Gastroenterology, 168(5), 965-979.e12. Advance online publication. https://doi.org/10.1053/j.gastro.2024.12.011More information about this publication
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Massen, M., Thijssen, M. S., Rademakers, G., Idris, M., Wouters, K. A. D., van der Meer, J. R. M., Buekers, N., Huijgen, D., Samarska, I. V., Weijenberg, M. P., van den Brandt, P. A., van Engeland, M., Gijbels, M. J., Boesmans, W., Smits, K. M., & Melotte, V. (2024). Neuronal distribution in colorectal cancer: associations with clinicopathological parameters and survival. Modern Pathology, 37(10), Article 100565. https://doi.org/10.1016/j.modpat.2024.100565More information about this publication
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Kuil, L. E., Chauhan, R. K., de Graaf, B. M., Cheng, W. W., Kakiailatu, N. J. M., Lasabuda, R., Verhaeghe, C., Windster, J. D., Schriemer, D., Azmani, Z., Brooks, A. S., Edie, S., Reeves, R. H., Eggen, B. J. L., Shepherd, I. T., Burns, A. J., Hofstra, R. M. W., Melotte, V., Brosens, E., & Alves, M. M. (2024). ATP5PO levels regulate enteric nervous system development in zebrafish, linking Hirschsprung disease to Down Syndrome. Biochimica et Biophysica Acta-Molecular Basis of Disease, 1870(3), Article 166991. https://doi.org/10.1016/j.bbadis.2023.166991More information about this publication
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Schonkeren, S. L., Thijssen, M. S., Idris, M., Wouters, K., de Vaan, J., Teubner, A., Gijbels, M. J., Boesmans, W., & Melotte, V. (2024). Differences in enteric neuronal density in the NSE-Noggin mouse model across institutes. Scientific Reports, 14(1), Article 3686. https://doi.org/10.1038/s41598-024-54337-wMore information about this publication
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Kakiailatu, N. J. M., Kuil, L. E., Bindels, E., Zink, J. T. M., Vermeulen, M., Melotte, V., & Alves, M. M. (2023). Gut Isolation from Zebrafish Larvae for Single-cell RNA Sequencing. Journal of visualized experiment, 2023(201), Article e65876. https://doi.org/10.3791/65876More information about this publication
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Idris, M., Coussement, L., Alves, M. M. M., De Meyer, T., & Melotte, V. (2023). Promoter hypermethylation of neural-related genes is compatible with stemness in solid cancers. Epigenetics & Chromatin, 16(1), Article 31. https://doi.org/10.1186/s13072-023-00505-7More information about this publication
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Schonkeren, S. L., Seeldrayers, S., Thijssen, M. S., Boesmans, W., Langen, R. C. J., & Melotte, V. (2023). An optimization and refinement of the whole-gut transit assay in mice. Neurogastroenterology and Motility, 35(8), Article e014586. https://doi.org/10.1111/nmo.14586More information about this publication
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Kuil, L. E., Kakiailatu, N. J. M., Windster, J. D., Bindels, E., Zink, J. T. M., van der Zee, G., Hofstra, R. M. W., Shepherd, I. T., Melotte, V., & Alves, M. M. (2023). Unbiased characterization of the larval zebrafish enteric nervous system at a single cell transcriptomic level. iScience, 26(7), Article 107070. https://doi.org/10.1016/j.isci.2023.107070More information about this publication
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Liu, D. H. W., Kim, Y.-W., Sefcovicova, N., Laye, J. P., Hewitt, L. C., Irvine, A. F., Vromen, V., Janssen, Y., Davarzani, N., Fazzi, G. E., Jolani, S., Melotte, V., Magee, D. R., Kook, M.-C., Kim, H., Langer, R., Cheong, J.-H., & Grabsch, H. I. (2023). Tumour infiltrating lymphocytes and survival after adjuvant chemotherapy in patients with gastric cancer: post-hoc analysis of the CLASSIC trial. British Journal of Cancer, 128(12), 2318-2325. https://doi.org/10.1038/s41416-023-02257-3More information about this publication