Dr V. Melotte

Thijssen, M. S., Chilà, R., Crisafulli, G., Smits, K. M., Bardelli, A., Boesmans, W., & Melotte, V. (2026). Neural cues differentially modulate colorectal cancer cell behavior depending on patients’ genomic background. iScience, 29(6), Article 116153. https://doi.org/10.1016/j.isci.2026.116153

Kakiailatu, N. J. M., Zhang, W., Kuil, L. E., Windster, J. D., Bindels, E., Zink, J. T. M., Vermeulen, M., de Graaf, B. M., Sahadew, D., van den Bosch, T. P. P., Huijgen, D., Sloots, C. E. J., Wijnen, R. M. H., Hofstra, R. M. W., de Pater, E., Melotte, V., & Alves, M. M. (2026). Impact of enteric neuronal loss on intestinal cell composition. iScience, 29(5), Article 115491. https://doi.org/10.1016/j.isci.2026.115491

Kakiailatu, N. J. M., Zhang, W., Kuil, L. E., Bindels, E., Zink, J. T. M., Vermeulen, M., de Pater, E., Melotte, V., & Alves, M. M. (2025). Retinoic Acid Inhibition Alters Intestinal Composition in Zebrafish: A Non-genetic Model to Study Hirschsprung Disease? Neurogastroenterology and Motility, 37(11), Article e70155. https://doi.org/10.1111/nmo.70155

Thijssen, M. S., Massen, M., van der Meer, J. R. M., Gijbels, M. J., Samarska, I. V., van Engeland, M., Weijenberg, M. P., van den Brandt, P. A., Smits, K. M., Boesmans, W., & Melotte, V. (2025). Clinicopathological characterization of enteric glia in colorectal cancer: Insights from a population-based cohort. Journal of neuropathology and experimental neurology, 84(10), 892-901. https://doi.org/10.1093/jnen/nlaf067

Tasnády, K. R., Jehoul, R., de Ravé, M. G., Gijbels, M. J., Brône, B., Dewachter, I., Melotte, V., & Boesmans, W. (2025). Gastrointestinal Dysfunction and Low-Grade Inflammation Associate With Enteric Neuronal Amyloid-β in a Model for Amyloid Pathology. Neurogastroenterology and Motility, 37(5), Article e15016. https://doi.org/10.1111/nmo.15016

Windster, J. D., Kakiailatu, N. J. M., Kuil, L. E., Antanaviciute, A., Sacchetti, A., MacKenzie, K. C., Peulen-Zink, J., Kan, T. W., Bindels, E., de Pater, E., Doukas, M., van den Bosch, T. P. P., Yousefi, S., Barakat, T. S., Meeussen, C., Sloots, C. E. J., Wijnen, R. M. H., Parikh, K., Boesmans, W., ... Alves, M. M. (2025). Human enteric glia diversity in health and disease: new avenues for the treatment of Hirschsprung disease. Gastroenterology, 168(5), 965-979.e12. https://doi.org/10.1053/j.gastro.2024.12.011

Massen, M., Thijssen, M. S., Rademakers, G., Idris, M., Wouters, K. A. D., van der Meer, J. R. M., Buekers, N., Huijgen, D., Samarska, I. V., Weijenberg, M. P., van den Brandt, P. A., van Engeland, M., Gijbels, M. J., Boesmans, W., Smits, K. M., & Melotte, V. (2024). Neuronal distribution in colorectal cancer: associations with clinicopathological parameters and survival. Modern Pathology, 37(10), Article 100565. https://doi.org/10.1016/j.modpat.2024.100565

Kuil, L. E., Chauhan, R. K., de Graaf, B. M., Cheng, W. W., Kakiailatu, N. J. M., Lasabuda, R., Verhaeghe, C., Windster, J. D., Schriemer, D., Azmani, Z., Brooks, A. S., Edie, S., Reeves, R. H., Eggen, B. J. L., Shepherd, I. T., Burns, A. J., Hofstra, R. M. W., Melotte, V., Brosens, E., & Alves, M. M. (2024). ATP5PO levels regulate enteric nervous system development in zebrafish, linking Hirschsprung disease to Down Syndrome. Biochimica et Biophysica Acta-Molecular Basis of Disease, 1870(3), Article 166991. https://doi.org/10.1016/j.bbadis.2023.166991

Schonkeren, S. L., Thijssen, M. S., Idris, M., Wouters, K., de Vaan, J., Teubner, A., Gijbels, M. J., Boesmans, W., & Melotte, V. (2024). Differences in enteric neuronal density in the NSE-Noggin mouse model across institutes. Scientific Reports, 14(1), Article 3686. https://doi.org/10.1038/s41598-024-54337-w

Kakiailatu, N. J. M., Kuil, L. E., Bindels, E., Zink, J. T. M., Vermeulen, M., Melotte, V., & Alves, M. M. (2023). Gut Isolation from Zebrafish Larvae for Single-cell RNA Sequencing. Journal of visualized experiment, 2023(201), Article e65876. https://doi.org/10.3791/65876