PhD conferral Mohamed Mohamed Rahouma Ahmed

Keywords: Cardiac tumors, angiosarcoma, outcomes, sex differences

"In-depth clinical investigations over cardiac tumors in adult patients"
 

• Primary malignant cardiac tumors (PMCTs) represent about 10% of primary cardiac tumors and survival is improved by treatment in specialized high-volume centers. A higher prevalence was noticed in Europe and North America.
• About 6% of PMCTs occurred in octogenarians vs. 9.8% in septuagenarians. The independent predictors of early and late mortality included octogenarian
• The median age of PMCTs was 52 and 47.8% were females. About 60% underwent surgery. Angiosarcoma (43%) was the most common pathology. No differences in late mortality between males and females in the National Cancer Database (NCDB)..
• Private insurance was associated with better survival in PMCTs.
• Geographic variation in PMCTs in the United States did not reflect on the outcomes.
• Minimally invasive and median sternotomy approaches to cardiac tumors were associated with excellent early and late outcomes with acceptable survival rates and low incidence of recurrences. 
• Surgery and chemotherapy were associated with longer survival benefits, while advanced age, higher comorbidity index, angiosarcoma histology, and stage III/IV were associated with shorter survival.
• While surgery is important in cardiac angiosarcoma, it is not the main utilized modality.

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