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Dr Lotte Lemmens (L.H.J.M.)

Research profile

Research interests

- Treatment studies

- Research conducted in clinical settings

- Cognitive (behavioural) therapy

- Interpersonal Psychotherapy

- (Cue) exposure

- Treatment outcomes

- Shape of change

- Mediators of treatment effects

- Optimal treatment selection

- Sudden Gains

- (Dynamic) Relations between symptoms

- Depression

- Eating Disorders

- Binge Eating

- EMA/EMI

- Network Theory

Research projects

Key projects:

- Beating the Binge (NWO Veni); 4-year project to understand and reduce binge eating in daily life (EMA, EMI, network analyses, self-learning e-coach) (principal investigator).

- New Science of Mental Disorders (NWO Gravitation): 10-year program to study the networks of interacting symptoms of psychopathology, the transdiagnostic processes that drive the connectivity between symptoms, and the effect of network-based interventions tailored for the individual patient (young talent).

- STEPd: RCT on the effects and mechanisms of CT vs. IPT for Depression (project coordinator).

- Bou2: RCT on the effects and mechanisms of CT vs. CT + cue exposure for Eating Disorders (project coordinator).

- Think Slim: Development of a tailored E‐coach­‐intervention for overweight people based on cognitive behavioral principles (EMA, EMI, Network analyses) (project group member).

- FreqMech: RCT on the effects of session frequency of psychotherapy (CT/IPT) for depression (project group member).

Recent publications
  • Penedo, J. M. G., Meglio, M., Flueckiger, C., Wienicke, F. J., Breunese, J., Menchetti, M., Rucci, P., Johansson, R., Towni, J. M., Abbassj, A. A., Lilliengren, P., Bagby, R. M., Quilty, L. C., Lemmens, L. H. J. M., van Bronswijk, S. C., Barkham, M., Stilesq, W. B., Hardy, G. E., Fonagy, P., ... Driessen, E. (2025). Interpersonal problems as a predictor of treatment outcome in adult depression: An individual participant data meta-analysis. Clinical Psychology Review, 118, Article 102570. Advance online publication. https://doi.org/10.1016/j.cpr.2025.102570
    More information about this publication
  • Melles, H., Lemmens, L., & Jansen, A. (2025). Intervention research in anorexia nervosa - a plea for single case experimental designs. Eating Disorders. Advance online publication. https://doi.org/10.1080/10640266.2025.2471218
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  • Jover Martínez, A., Lemmens, L. H. J. M., Fried, E. I., Guðmundsdóttir, G. R., & Roefs, A. (2025). Validation of a transdiagnostic psychopathology ecological momentary assessment protocol in a university student sample. Psychological Assessment, 37(1-2), 46-61. https://doi.org/10.1037/pas0001348
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  • Bär, A., Heininga, V. E., Lemmens, L. H. J. M., & Renner, F. (2024). From anticipation to action: A RCT on mental imagery exercises in daily life as a motivational amplifier for individuals with depressive symptoms. Applied Psychology-Health and Well Being, 16(4), 1988-2005. https://doi.org/10.1111/aphw.12572
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  • Jover Martinez, A., Lemmens, L. H. J. M., Fried, E. I., & Roefs, A. (2024). Developing a transdiagnostic Ecological Momentary Assessment protocol for psychopathology. International Journal of Methods in Psychiatric Research, 33(3), Article e2028. https://doi.org/10.1002/mpr.2028
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  • Pryor, J. B., Stutterheim, S. E., & Lemmens, L. H. J. M. (2024). The relationships of sexually harassing behaviors to organizational context factors and working men's dark personality traits. Aggressive behavior, 50(2), Article e22142. https://doi.org/10.1002/ab.22142
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  • Bruijniks, S. J. E., Hollon, S. D., Lemmens, L. H. J. M., Peeters, F. P. M. L., Arntz, A., Cuijpers, P., Twisk, J., Dingemanse, P., Willems, L., van Oppen, P., van den Boogaard, M., Spijker, J., & Huibers, M. J. H. (2024). Long-term outcomes of once weekly v. twice weekly sessions of cognitive behavioral therapy and interpersonal psychotherapy for depression. Psychological Medicine, 54(3), 517-526. https://doi.org/10.1017/S0033291723002143
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  • Bosmans, J. E., Bruijniks, S. J. E., El Alili, M., Hollon, S. D., Peeters, F. P. M. L., Arntz, A., Cuijpers, P., Lemmens, L. H. J. M., Dingemanse, P., Willems, L., van Oppen, P., van den Boogaard, M., Spijker, J., Twisk, J. W. R., & Huibers, M. J. H. (2023). Cost-effectiveness of twice-weekly versus once-weekly sessions of cognitive-behavioural therapy and interpersonal psychotherapy for depression at 12 months after start of treatment: randomised controlled trial. Bjpsych open, 9(6), Article e186. https://doi.org/10.1192/bjo.2023.548
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  • Huibers, M. J. H., Van Bronswijk, S. C., Peeters, F. P. M. L., & Lemmens, L. H. J. M. (2022). Does psychological process change during psychotherapy predict long-term depression outcome after successful cognitive therapy or interpersonal psychotherapy? Secondary analysis of a randomized trial. Psychotherapy Research, 32(8), 1047-1063. https://doi.org/10.1080/10503307.2022.2064251
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  • Daruvala, R., Roefs, A., Desjardins, L., Bhat, S., Datta, S., & Lemmens, L. (2022). EP538 / #1274 Understanding And Improving Feeding And Eating Practices In Children With Cancer In India: Developing A Manualized Psychological Family Intervention. Pediatric Blood & Cancer, 69(S5), S397-S397. https://doi.org/10.1002/pbc.29952
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Other publications

- Schyns, GTL, Lemmens, LHJM, & Jansen, A (in press). Cue Exposure Therapie. In: A. van Emmerik, & A. Greeven (Eds). Handboek exposure. Amsterdam: Boom Psychologie & Psychiatrie.

 

- Lemmens, LHJM, van Bronswijk, SC, Peeters, F, Arntz, A, Roefs, A, Hollon SD, DeRubeis RJ & Huibers, MJH (2020). Interpersonal psychotherapy vs cognitive therapy for major depressive disorder: how do they work, how long and for whom? Results from a randomized trial. The American Journal of Psychotherapy. E-Pub ahead of print. 

 

- Dingemans, A, Wezenberg, E, Claes, L, Jansen, A, & Lemmens, LHJM (2020). Nederlandse vertaling van de Eating Disorder Examination 17.0. E-Pub ahead of print. 

 

- Bruijniks, SJE, Lemmens, LHJM, Hollon, SD, Peeters, FPML, Cuijpers, P, Arntz, A, Dingemanse, P, Willems, L, van Oppen, P, Twisk, J, van den Boogard, M, Spijker, J, Bosmans, J & Huibers, MJH (2020). Seeing depressed patients twice a week improves psychotherapy outcomes: multicentre randomized trial comparing session frequencies in CBT and IPT. The British Journal of Psychiatry. E-Pub ahead of print. 

 

- Lorenzo-Luaces, L, Lemmens, LHJM, Keefe, JR, Cuijpers, P, & Bockting CLH (in press). The efficacy of cognitive behavioral therapy for depression and anxiety: An updated review of meta-analyses. In A. E. Wenzel, (Ed.) Handbook of Cognitive Behavioral Therapy.

 

- van Bronswijk, SC, DeRubeis, RJ, Lemmens, LHJM, Peeters, F, Keefe, JR, Cohen, ZD & Huibers, MJH (2019). Precision medicine for long-term depression outcomes using the Personalized Advantage Index approach: cognitive therapy or interpersonal psychotherapy? Psychological Medicine. E-Pub ahead of print. 

 

- Roefs, A, Boh, B, Spanakis, G, Nederkoorn, C, Lemmens, LHJM & Jansen, A (2019). Food craving in daily life: comparison of overweight and normal-weight participants with ecological momentary assessment. Journal of Human Nutrition and Dietetics, 32(6), 765-774.

 

- Lemmens, LHJM, van Bronswijk, SC, Peeters, F, Arntz, A, Roefs, A, Hollon SD, DeRubeis RJ & Huibers, MJH (2019). Cognitieve Therapie en Interpersoonlijke Psychotherapie voor Depressie: hoe werken ze, hoelang, en voor wie? Tijdschrift voor Psychiatrie, 61, 710-719.

 

- Roefs, A, Lemmens LHJM & Jansen, A (2019). Eetstoornissen als een netwerk van symptomen.  Gedragstherapie, 52 (1), 69-90.

 

- van Bronswijk, SC, Lemmens, LHJM, Keefe, JR, Huibers, MJH, DeRubeis, RJ & Peeters, F (2019). A prognostic index for long-term outcomes after successful acute phase Cognitive Therapy and Interpersonal Psychotherapy for Major Depressive Disorder. Depression and Anxiety, 36(3), 252-261. 

 

- Bockting, CLH & Lemmens, LHJM (2019). Cognitieve Therapie bij Depressieve Stoornissen. In S.M. Bögels & P. van Oppen (Eds.), Cognitieve Therapie: Theorie en Praktijk (pp 69-101). Houten: Bohn Stafleu van Loghum.

 

- Lemmens, LHJM, van Bronswijk, SC, Peeters, F, Arntz, A, Hollon, SD & Huibers, MJH (2019). Long-term Outcomes of Acute Treatment with Cognitive Therapy vs. Interpersonal Psychotherapy for Adult Depression: Follow-up of a Randomized Controlled Trial. Psychological Medicine, 49(3), 465-473.

 

- Lemmens, LHJM, & Huibers, MJH (2018). Wat weten we eigenlijk over de werkingsmechanismen van psychotherapie voor depressie? En waarom is dat nog maar zo weinig. Tijdschrift voor Psychotherapie, 44(6), 364-393.

 

- Lemmens, LHJM & Roelofs, J (2018). Cognitieve Gedragstherapie. In E. Simon, G. Smeets, H.T. van der Molen, P. Muris & E. Hullu (Eds.), Klinische Psychologie: Diagnostiek en Therapie (pp 135-163). Groningen: Noordhoff Uitgevers.

 

- Van Bronswijk, SC, Lemmens, LHJM, Huibers, MJH, Arntz, A, & Peeters, FPML (2018). The Influence of Comorbid Anxiety on the effectiveness of Cognitive Therapy and Interpersonal Psychotherapy for Major Depressive Disorder. Journal of Affective Disorders, 232, 52-60.

 

- Van Bronswijk, SC, Lemmens, LHJM, Viechtbauer, W, Huibers, MJH, Arntz, A, & Peeters, FPML (2018). The impact of personality disorder pathology on the effectiveness of Cognitive Therapy and Interpersonal Psychotherapy for Major Depressive Disorder. Journal of Affective Disorders, 225, 530-538. 

 

- Lemmens, LHJM, Galindo-Garre, F, Arntz, A, Peeters, F, Hollon, SD, DeRubeis, RJ, & Huibers, MJH (2017). Exploring Mechanisms of Change in Cognitive Therapy and Interpersonal Psychotherapy for adult Depression. Behaviour Research and Therapy, 94, 81-92

 

- Lemmens, LHJM, DeRubeis, RJ, Arntz. A, Peeters, F, & Huibers,  MJH (2017). En opeens ging het beter! De rol van Sudden Gains in Cognitieve Therapie en Interpersoonlijke Therapie voor Depressie. Gedragstherapie, 50 (2), 102-122.

 

- Spanakis, G, Weiss, G, Boh, B, Lemmens, LHJM, & Roefs, A. (2017). Machine learning techniques in eating behavior e-coaching: balancing between generalization and personalization. Personal and Ubiquitous Computing, DOI 10.1007/s00779-017-1022-4

 

- Meesters, C, Muris, P, Dibbets, P, Cima, M, & Lemmens, LHJM (2017). Feeling loved or rejected: On the link between perceived parental rearing behaviors and self-conscious emotions in adolescents. Journal of Child and Family Studies, 26, 1536-1545. 

 

- Lemmens, LHJM & DeRubeis, RJ (2017). Sudden Gains. In Wenzel, A. (Editor in Chief), Encyclopedia of Abnormal and Clinical Psychology (pp 3395-3396). Thousand Oaks: SAGE Publications.

 

- Lemmens, LHJM, Müller, VNLS, Arntz, A, & Huibers, MJH (2016). Mechanisms of Change in Psychotherapy for Depression: An empirical update and evaluation of research aimed at identifying psychological mediators. Clinical Psychology Review, 50, 95 - 107.

 

- Boh, B, Jansen, A, Clijsters, I, Nederkoorn, C, Lemmens, LHJM, Spanakis, G, & Roefs, A (2016). Indulgent thinking. Ecological Momentary Assessment of Overweight and Healthy-weight Participants’ Cognitions and Emotions. Behaviour Research and Therapy, 87, 196-206.

 

- Boh, B, Lemmens, LHJM, Jansen, A, Nederkoorn, C, Kerkhofs, V, Spanakis, G, Weiss, G, & Roefs, A (2016). An ecological momentary intervention via smartphone and internet: Study protocol for a randomised controlled trial for weight loss and healthy eating. Trials, 17, 154-166.

 

- Lemmens, LHJM, DeRubeis, RJ., Arntz. A, Peeters, F, & Huibers, MJH (2016). Sudden Gains in Cognitive Therapy and Interpersonal Psychotherapy for adult Depression. Behaviour Research and Therapy, 77, 170-176.

 

- Huibers, MJH, Cohen, ZD, Lemmens, LHJM, Arntz, A, Peeters, FPML, Cuijpers, P, & DeRubeis, RJ (2015). Predicting Optimal Outcomes in Cognitive Therapy or Interpersonal Psychotherapy for Depressed Individuals Using the Personalized Advantage Index Approach. PLoS ONE, 10 (11); e0140771. doi: 10.1371/journal.pone.0140771.

 

- Lemmens, LHJM, Renner, F, & Peeters, F (2015). Persisterende Depressieve Stoornis. In I. Franken, P. Muris & D. Denys (Eds.), Basisboek Psychopathologie (pp 231-242). Utrecht: de Tijdstroom.

 

- Lemmens, LHJM, Arntz, A, Peeters, F, Hollon, SD, Roefs, A, & Huibers, MJH (2015). Clinical Effectiveness of Cognitive Therapy vs. Interpersonal Psychotherapy for Depression: Results of a Randomised Controlled Trial. Psychological Medicine, 45, 2095-2110.

 

- Bringmann, LF, Lemmens, LHJM, Huibers, MJH, Borsboom, D, & Tuerlinckx, F (2015). Revealing the dynamic network structure of the Beck Depression Inventory-II. Psychological Medicine, 45, 747-757.

 

- Lemmens, LHJM, Roefs, A, Arntz, A, van Teeseling, HC, Peeters, F, & Huibers, MJH (2014). The value of an implicit self-associative measure specific to core beliefs of depression. Journal of Behavior Therapy and Experimental Psychiatry, 45(1), 196-202.

 

- Lemmens, LHJM, Arntz, A, Peeters, FPML, Hollon, SD, Roefs, A, & Huibers, MJH (2011). Effectiveness, relapse prevention and mechanisms of change of cognitive therapy vs. interpersonal therapy for depression: study protocol for a randomised controlled trial. Trials, 12, 150-162.

 

- Lemmens, LHJM, & Huibers, MJH (2011). Psychotherapie voor depressie werkt! Maar Hoe? Stand van zaken van onderzoek naar werkingsmechanismen. GZ-Psychologie, 8, 10-16.

Notes

HONORS AND AWARDS

 

2020 - Horizon 2020 Information and Communication Technologies grant (co-applicant)

 

2019 - Young Talent in NWO Gravitation consortium 'New Science of Mental Disorders'. 

 

2019 - Nomination FPN Education Prize (best master course coordinator). Maastricht University (top 4).

 

2018 - FPN Education Prize (best master course coordinator). Maastricht University, FPN.

 

2017 - Pieter Boeke Prijs (best dissertation in the field of psychotherapy). Pieter Boeke Foundation, Stichting PAO-P.

 

2017 - Veni (NWO). Project: Beating the Binge: A network approach to understand and reduce binge eating behaviour in daily life.

 

2016 - Article Prize (best paper) Dutch-Flemish Postgraduate School for Experimental Psychopathology (EPP)

 

2015 - Nomination for Wim Trijsburg Prize for Junior Scientists, Dutch association for Psychotherapy (NVP) (top 3). 

 

2014 - Beck Institute Graduate Student Scholarship, Beck Institute, Philadelphia (VS).

 

2013 - Grant University Fund Limburg /SWOL: for organizing Depression Symposium.

 

2012 - Fulbright Award & Scholarship, Fulbright Center Amsterdam.

 

2012 - Nomination FHML Educational Prize 2012 (best tutor), Universiteit Maastricht (top 5).

 

2011 - Grant University Fund Limburg /SWOL: Sudden Gains project.