Prof Dr F.C.S. Ramaekers

Mestrum, S. G. C., Schoenmakers, T., Wang, S. J., de Wit, N. C. J., Boonen, B. T., van Hemert, W. L. W., Deneer, R., Hopman, A. H. N., Ramaekers, F. C. S., & Leers, M. P. G. (2025). Increased anti-apoptotic (Bcl-2+) and decreased proliferative (Ki-67+) cell fractions during the different maturation stages of bone marrow cell populations in MDS and AML: The potential diagnostic impact of the Bcl-2. Cytometry. Part B, Clinical cytometry, 108(2), 146-160. https://doi.org/10.1002/cyto.b.22231

Mestrum, S. G. C., Roanalis, B. Y. V., de Wit, N. C. J., Drent, R. J. M., Boonen, B. T., van Hemert, W. L. W., Hopman, A. H. N., Ramaekers, F. C. S., & Leers, M. P. G. (2024). MDS and AML show elevated fractions of CD34-positive blast cell populations with a high anti-apoptotic versus proliferation ratio. Leukemia Research, 142, Article 107520. https://doi.org/10.1016/j.leukres.2024.107520

Moshi, J. M., Ummelen, M., Smedts, F., Ramaekers, F. C. S., & Hopman, A. H. N. (2024). Inhibition of cytosine 5-hydroxymethylation during progression of cancer precursor lesions in the uterine cervix. PLOS ONE, 19(4), Article e0297008. https://doi.org/10.1371/journal.pone.0297008

Mestrum, S. G. C., Vanblarcum, R., de Wit, N. C. J., Drent, R. J. M., Boonen, B. T., van Hemert, W. L. W., Hopman, A. H. N., Ramaekers, F. C. S., & Leers, M. P. G. (2023). Impact of the gating strategy for Ki-67 and Bcl-2 on the determination of proliferation and anti-apoptosis data by flow cytometry in non-malignant bone marrow aspirates and aspirates from patients with myeloid malignancies. Data in brief, 49(1), Article 109284. https://doi.org/10.1016/j.dib.2023.109284

Moshi, J. M., Ummelen, M., Broers, J. L. V., Ramaekers, F. C. S., & Hopman, A. H. N. (2023). Impact of antigen retrieval protocols on the immunohistochemical detection of epigenetic DNA modifications. Histochemistry and Cell Biology, 159(6), 513-526. https://doi.org/10.1007/s00418-023-02187-4

Mestrum, S. G. C., de Wit, N. C. J., Cremers, E. M. P., Drent, R. J. M., Ramaekers, F. C. S., Hopman, A. H. N., & Leers, M. P. G. (2022). The Proliferation Index of Erythroid Cells Predicts the Development of Transfusion-dependence in Myelodysplastic Syndrome Patients With Mildly Reduced Hemoglobin Levels at Initial Diagnosis. HemaSphere, 6(12), Article e804. https://doi.org/10.1097/HS9.0000000000000804

Moshi, J. M., Ummelen, M., Broers, J. L. V., Smedts, F., Van de Vijver, K. K., Cleutjens, J. P. M., Litjens, R. J. N. T. M., Ramaekers, F. C. S., & Hopman, A. H. N. (2022). SOX2 expression in the pathogenesis of premalignant lesions of the uterine cervix: its histo-topographical distribution distinguishes between low- and high-grade CIN. Histochemistry and Cell Biology, 158(6), 545-559. https://doi.org/10.1007/s00418-022-02145-6

Bergshoeff, V. E., Balkenhol, M. C. A., Haesevoets, A., Ruland, A., Chenault, M. N., Nelissen, R. C., Peutz, C. J., Clarijs, R., Van der Laak, J. A. W. M., Takes, R. P., Van den Brekel, M. W., Van Velthuysen, M.-L. F., Ramaekers, F. C. S., Kremer, B., & Speel, E.-J. M. (2022). Evaluation Criteria for Chromosome Instability Detection by FISH to Predict Malignant Progression in Premalignant Glottic Laryngeal Lesions. Cancers, 14(13), Article 3260. https://doi.org/10.3390/cancers14133260

Mestrum, S. G. C., Vanblarcum, R. B. Y., Drent, R. J. M., Boonen, B. T., van Hemert, W. L. W., Ramaekers, F. C. S., Hopman, A. H. N., & Leers, M. P. G. (2022). Proliferative and anti-apoptotic fractions in maturing hematopoietic cell lineages and their role in homeostasis of normal bone marrow. Cytometry Part A, 101(7), 552-563. https://doi.org/10.1002/cyto.a.24558

Stiekema, M., Houben, F., Verheyen, F., Borgers, M., Menzel, J., Meschkat, M., van Zandvoort, M. A. M. J., Ramaekers, F. C. S., & Broers, J. L. V. (2022). The Role of Lamins in the Nucleoplasmic Reticulum, a Pleiomorphic Organelle That Enhances Nucleo-Cytoplasmic Interplay. Frontiers in Cell and Developmental Biology, 10, Article 914286. https://doi.org/10.3389/fcell.2022.914286