02 Oct

Modelling human metabolism

The Netherlands has a large and strong community of researchers that are involved in mechanistic modelling of human metabolism. We believe that by joining forces, we can greatly accelerate progress in this field. This workshop will bring together researchers from various relevant communities (e.g., modellers, experimentalists, clinicians) to discuss the concepts, methods, opportunities, and challenges in the field.

We aim to create a multidisciplinary platform to address how metabolic modelling can answer important scientific questions and contribute to applications in disease, nutrition, and drug metabolism and what needs to be done to achieve this. The result of this workshop will be a community-agreed research agenda for the (near) future.

The workshop will be a 1-day workshop (max. 50 participants) consisting of two sessions with short presentations outlining approaches used, challenges identified, and collaborations needed, followed by longer, moderated discussions.

Topics

Morning
Different approaches to metabolic modelling:
  • constraint-based modelling
  • dynamic models
  • how to combine these
Different scales of modelling:
  • (sub)cellular, tissue
  • whole-organism
  • ecosystems
Afternoon
Community building
Agenda setting

For whom?

Researchers from various relevant communities (e.g., modellers, experimentalists, clinicians)