E.J. Vrij, MSc

Dr. Erik Vrij holds a PI position at the Department of Gynaecology and Obstetrics and works in partnership with the mouse synthetic embryo project at the MERLN Institute for Technology-Inspired Regenerative Medicine. His expertise in stem cell-based embryo models and micro-engineered platforms, along with his collaborative efforts with clinicians, (epi)geneticists, embryologists, bioengineers, and biologists, allows him to pinpoint the critical processes that contribute to reproductive success. Specifically, he and his team are developing mouse and human stem cell-based embryo models and using micro-engineered microenvironments, such as the endometrium-on-chip, to study peri- and post-implantation development. This approach will enhance our understanding of early embryo development and the interplay with maternal tissues during conception, implantation, and early placentation. With the strong connections to the clinic, Erik Vrij aims to bridge the gap between stem cell-based in vitro models and clinical applications to ultimately improve the safety and efficiency of reproduction and reproductive techniques, including in vitro fertilization and diagnostics, and improve maternal and child long-term health outcome.