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… Medicine is complicated. @micheldumontier::KE@Work:2017-01-26 9 we need new ways to think about discovery science using more knowledge while paying attention to reproducibility Our confidence in a finding is strengthened when found in multiple independent datasets of the same type 10 A common rejection module (CRM) for acute rejection across multiple organs identifies novel therapeutics for organ transplantation Khatri et al. JEM. 210 (11): 2205 DOI: 10.1084/jem.20122709 @micheldumontier::KE@Work:2017-01-26 11 Known to be associated through perturbation expts. Mentioned in scientific text together Interact with known genes … Use statistical methods to find significant patterns and predictive models. Our confidence in a finding is strengthened when we can uncover evidence at multiple levels A study to examine what support exists for the role of genes in aging in the worm. @micheldumontier::KE@Work:2017-01-26 How …

… March 2020 3 • Noor Bloemen (ESST student) • Geert Somsen (Program Director) • not: Thomas Verra (student ambassador) – in Athens doing his ESST specialization your presenters today 4 me: • What is ESST about? • What does the program look like? • What can you do with it? • What do you need to enter? Noor: • What is ESST like when you do it? • Living in Maastricht today’s presentations 5 • Society, Science, and Technology • … • ??? • example: Black Mirror, episode “Nose Dive” What is ESST about? 9 We live in a Technological Culture Ethics Cultural norms Economics and …