Prof Dr P. Lambin
SUMMARY: Philippe Lambin is a Clinician scientist, Radiation Oncologist, “ERC advanced & twice ERC PoC grant laureate” respectively from 2016, 2017 & 2020 and pioneer in translational research with a focus on tumour hypoxia; genetically modified bacteria for cancer treatment and Decision Support Systems. He has a PhD in Molecular Radiation Biology and is Professor at the University of Maastricht (Precision Medicine) and at the University of Eindhoven (“Functional Imaging”, until 2011). He is co-author of more than 620 peer reviewed scientific papers (https://orcid.org/0000-0001-7961-0191, more than 60K citations, Hirsch Index: 120 Google scholar; co-inventor of more than 22 patent families (filed or submitted) of which 10 are in the (pre)commercialization phase and (co) promoter of more than 72 completed PhD’s (2 with cum laude).
Moreover, Prof. P. Lambin has extensive experience with clinical trials. He has been one of the international experts in the Flims workshop “Methods in Clinical Cancer Research organised jointly by the FECS, AACR and ASCO and he is leading several clinical trials (see www.clinicaltrials.gov: his name is mentioned as Principal Investigator in 30 clinical trials). He has been also a member of the scientific committee of KWF (the main Dutch funding body in cancer research) and of the advice committee on protontherapy of CVZ (the Dutch medical insurance). He has been and is currently involved in several successful European grants (e.g. CDPT, Biocare, Euroxy, Metoxia, Eureca, Artforce, RADIATE, Quick-Concept, Requite, BD2decide, SCANnTREAT, EuCanImage, CHAIMELEON, DRAGON, iCOVID, AUTO.DISTINCT, LIVINGVAC, OPTIMA, AIDAVA, REALM, EUCAIM, GLIOMATCH…) including ImmunoSABR (6 millions €, a multicentric randomized trial in metastatic lung cancer comparing radiotherapy plus or minus immunotherapy) and the Marie Curie Training network PREDICT of which he is the initiator and the coordinator and two NIH grant (“Radiomics”) form the US. His main areas of interest are directed towards translational research in tumour Biology with a specific focus on tumour hypoxia, functional imaging (Radiomics), lung and head and neck cancer. More recently, his interests have been directed towards hypoxia targeting, Hypoxia Activated Prodrugs, during immunotherapy, genetically modified bacteria as living medicine and the development of “AI-based treatment decision support system” based on multiparametric databases containing clinical, imaging, biological and therapeutic information, and taking into account patient preferences. The website he launched, ai4cancer.ai with validated predictive models has had more than 20.000 visitors from more than 133 countries.
He is one of the co-inventor of “Radiomics”, “Clinical Decision Support Systems”, “Distributed learning” from federated databases, genetically modified bacteria for cancer treatment in particulat CMIT), the combination of immunocytokines with radiation, Lymphocytes-Sparing Radiotherapy (LSRT, also named “Drugless Radiotherapy”) and MEDomics. More information on his work for third parties: https://www.maastrichtuniversity.nl/p-lambin/work-for-third-parties (focused on present and future activities) and https://coi.asco.org/share/75N-CPEH/Philippe%20Lambin (focused on the activities of the past two years).
Artificial Intelligence, Decision Support Systems, Radiation Oncology, Tumor Hypoxia, Hypoxia Activated Prodrugs, Functional Imaging/Radiomics, Big Data, Distributed Learning, Immunocytokines, Clostridium-based therapies, Deep Learning, Artificial Intelligence, mitochondrial DNA, Technology Transfer ("from the mines (the universities) to the Mill (the companies)").
Prof Dr P. Lambin
MD, PhD, RadOnc & Principal Investigator in the Dpt of Precision Medicine (www.precisionmedicine.eu):The D-Lab (data sciences lab), the M-Lab group (biology lab) and The Clinical Trial Unit (Phase 1, 2 Clinical trials, prospective studies and "In Silico" Clinical trials)