26 Nov

On-Site PhD conferral Ruud A.F. Verhees

Supervisors: Prof. dr. G.J. Dinant, Prof. dr. J.A. Knottnerus

Co-supervisor: Dr. C.T. Thijs

Key words: influenza, vaccination, elderly, primary care

"Contributions to the evidence base for reducing the impact of influenza in primary care"

Influenza can have a significant impact on both individual and societal level. This can be reduced by vaccination and usage of point-of-care tests in specific settings like the Emergency Department. De general physician plays a key role in implementing influenza vaccination. The attitude of the Dutch general physician towards influenza vaccination is generally in favour of vaccination, which is reflected by a majority of the GPs that is vaccinated against the flu and advises practice personnel to get vaccinated. This thesis found indications of a possible relevant effect of influenza vaccination on mortality in the younger elderly. Also, after extensive ethical and methodological considerations, it appears unlikely that a randomized controlled trial evaluating the long-term effect of influenza vaccination on mortality will ever be conducted. This thesis stresses the potency of long-term follow-up of intervention studies and the importance of considering ethical and methodological aspects of research when it comes to developing new influenza vaccination trials.

Click here for the full dissertation.

Click here for the live stream.