01 Oct
15:30 - 16:30
MaCSBio Lecture Series

Magnetic resonance spectroscopy to study human brain

Magnetic resonance spectroscopy (MRS) is a non-invasive technique that allows the measurement of multiple metabolites in the brain in vivo at the same time.​ Dr. Malgorzata Marjanska (Center for Magnetic Resonance Research, Department of Radiology, University of Minnesota, USA) will present a lecture: 'Magnetic Resonance Spectroscopy to Study Human Brain' for the MaCSBio Lecture Series. 

Abstract

Magnetic resonance spectroscopy (MRS) is a non-invasive technique that allows the measurement of multiple metabolites in the brain in vivo at the same time. These MR visible metabolites are primarily located in the intracellular compartments and preferentially concentrated in certain cell types. For instance, N-acetylasparate and glutamate are predominantly located in neurons, total creatine (creatine + phosphocreatine) and choline containing compounds are found in both neuronal and glial cells, and myo-inositol is thought to be localized exclusively in astrocytes.

In this presentation, Dr. Marjanska will focus on the use of MRS to study human brain including aging and brain tumors.

About MaCSBio

MaCSBio is a joint initiative of the Faculty of Psychology and Neuroscience, Faculty of Health, Medicine and Life Science and the Faculty of Humanities and Sciences. To achieve scientific breakthroughs that could not be achieved in individual labs, the centre brings together the expertise of physicians, biologists, mathematicians and computer scientists.

MaCSBio aims to develop a set of computational and mathematical models, applicable in science and clinic, that will advance our understanding of biological systems, and predict progression and treatment of complex diseases over time. 

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The Maastricht Centre for Systems Biology (MaCSBio) was launched in 2015