A.J. Groot

Menegakis, A., Vennin, C., Ient, J., Groot, A. J., Krenning, L., Klompmaker, R., Friskes, A., Ilic, M., Yaromina, A., Harkes, R., van den Broek, B., Jakob Sonke, J., De Jong, M., Piepers, J., van Rheenen, J., Vooijs, M. A., & Medema, R. H. (2025). A novel lineage-tracing tool reveals that hypoxic tumor cells drive tumor relapse after radiotherapy. Radiotherapy and Oncology, 202, Article 110592. https://doi.org/10.1016/j.radonc.2024.110592

Hounjet, J., Groot, A. J., Piepers, J. P., Kranenburg, O., Zwijnenburg, D. A., Rapino, F. A., Koster, J. B., Kampen, K. R., & Vooijs, M. A. (2023). Iron-responsive element of Divalent metal transporter 1 (Dmt1) controls Notch-mediated cell fates. The FEBS journal, 290(24), 5811-5834. https://doi.org/10.1111/febs.16946

Vermeer, J. A. F., Ient, J., Markelc, B., Kaeppler, J., Barbeau, L. M. O., Groot, A. J., Muschel, R. J., & Vooijs, M. A. (2020). A lineage-tracing tool to map the fate of hypoxic tumour cells. Disease Models & Mechanisms, 13(7), Article 044768. https://doi.org/10.1242/dmm.044768

Giuranno, L., Roig, E. M., Wansleeben, C., van den Berg, A., Groot, A. J., Dubois, L., & Vooijs, M. (2020). NOTCH inhibition promotes bronchial stem cell renewal and epithelial barrier integrity after irradiation. Stem Cells Translational Medicine, 9(7), 799-812. https://doi.org/10.1002/sctm.19-0278

Gong, Y., Wolterink, R. G. J. K., Janssen, I., Groot, A. J., Bos, G. M. J., & Germeraad, W. T. V. (2020). Rosuvastatin Enhances VSV-G Lentiviral Transduction of NK Cells via Upregulation of the Low-Density Lipoprotein Receptor. Molecular Therapy - Methods and Clinical Development, 17, 634-646. https://doi.org/10.1016/j.omtm.2020.03.017

Giuranno, L., Wansleeben, C., Iannone, R., Arathoon, L., Hounjet, J., Groot, A. J., & Vooijs, M. (2019). NOTCH signaling promotes the survival of irradiated basal airway stem cells. American Journal of Physiology-Lung Cellular and Molecular Physiology, 317(3), L414-L423. https://doi.org/10.1152/ajplung.00197.2019

Hounjet, J., Habets, R., Schaaf, M. B., Hendrickx, T. C., Barbeau, L. M. O., Yahyanejad, S., Rouschop, K. M., Groot, A. J., & Vooijs, M. (2019). The anti-malarial drug chloroquine sensitizes oncogenic NOTCH1 driven human T-ALL to γ-secretase inhibition. Oncogene, 38(27), 5457-5468. https://doi.org/10.1038/s41388-019-0802-x

Othman, Z., Fernandes, H., Groot, A. J., Luider, T. M., Alcinesio, A., Pereira, D. D. M., Guttenplan, A. P. M., Yuan, H., & Habibovic, P. (2019). The role of ENPP1/PC-1 in osteoinduction by calcium phosphate ceramics. Biomaterials, 210, 12-24. https://doi.org/10.1016/j.biomaterials.2019.04.021

Roig, E. M., Groot, A. J., Yaromina, A., Hendrickx, T. C., Barbeau, L. M. O., Giuranno, L., Dams, G., Ient, J., Pimentel, V. O., van Gisbergen, M. W., Dubois, L. J., & Vooijs, M. A. (2019). HIF-1α and HIF-2α Differently Regulate the Radiation Sensitivity of NSCLC Cells. Cells, 8(1), Article 45. https://doi.org/10.3390/cells8010045

Iglesias, V. S., van Hoof, S. J., Vaniqui, A., Schyns, L. E., Lieuwes, N., Yaromina, A., Spiegelberg, L., Groot, A. J., Verhaegen, F., Theys, J., Dubois, L., & Vooijs, M. (2019). An orthotopic non-small cell lung cancer model for image-guided small animal radiotherapy platforms. British Journal of Radiology, 92(1095), Article 20180476. https://doi.org/10.1259/bjr.20180476