L. Temmerman
Recent publications
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Saar-Kovrov, V., Pawlowska, A., Guillot, A., Gijbels, M. J. J., Sluimer, J. C., Temmerman, L., Goossens, P., Mees, B. M. E., Tacke, F., Jankowski, V., Jankowski, J., Donners, M. M. P. C., & Biessen, E. A. L. (2025). Correction: Protein carbamylation in atherosclerotic plaques correlates with uremia and disease progression, localizing predominantly to foam cells. Frontiers in Immunology, 16, Article 1637511. https://doi.org/10.3389/fimmu.2025.1637511More information about this publication
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Saar-Kovrov, V., Pawlowska, A., Guillot, A., Gijbels, M. J. J., Sluimer, J. C., Temmerman, L., Goossens, P., Mees, B. M. E., Tacke, F., Jankowski, V., Jankowski, J., Donners, M. M. P. C., & Biessen, E. A. L. (2025). Protein carbamylation in atherosclerotic plaques correlates with uremia and disease progression, localizing predominantly to foam cells. Frontiers in Immunology, 16, Article 1532250. https://doi.org/10.3389/fimmu.2025.1532250More information about this publication
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Vermeulen, I., Li, M., van Mourik, H., Yadati, T., Eijkel, G., Balluff, B., Godschalk, R., Temmerman, L., Biessen, E. A. L., Kulkarni, A., Theys, J., Houben, T., Cillero-Pastor, B., & Shiri-Sverdlov, R. (2025). Inhibition of intracellular versus extracellular cathepsin D differentially alters the liver lipidome of mice with metabolic dysfunction-associated steatohepatitis. FEBS Journal, 292(7), 1781-1797. https://doi.org/10.1111/febs.17358More information about this publication
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van Mourik, H., Westheim, A., Schneider, C. V., Stoffels, L., Wieczerzak, E., Steeghs, J., Schneider, K. M., Temmerman, L., Biessen, E., Godschalk, R., Theys, J., & Shiri - Sverdlov, R. (2025). Extracellular Cathepsin B Is a potential Therapeutic Target in Hepatocellular Carcinoma. Liver International, 6(1), Article e70016. https://doi.org/10.1002/lci2.70016More information about this publication
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Medina, I., Wieland, E. B., Temmerman, L., Otten, J. J. T., Bermudez, B., Bot, I., Rademakers, T., Wijnands, E., Schurgers, L., Mees, B., van Berkel, T. J. C., Goossens, P., & Biessen, E. A. L. (2024). Colony stimulating factor 1 receptor (Csf1r) expressing cell ablation in mafia (macrophage-specific Fas-induced apoptosis) mice alters monocyte landscape and atherosclerotic lesion characteristics. European Journal of Immunology, 54(11), Article 2350943. https://doi.org/10.1002/eji.202350943More information about this publication
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Christ, A., Maas, S. L., Jin, H., Lu, C., Legein, B., Wijnands, E., Temmerman, L., Otten, J., Isaacs, A., Zenke, M., Stoll, M., Biessen, E. A. L., & van der Vorst, E. P. C. (2024). In situ lipid-loading activates peripheral dendritic cell subsets characterized by cellular ROS accumulation but compromises their capacity to prime naïve T cells. Free Radical Biology and Medicine, 210, 406-415. https://doi.org/10.1016/j.freeradbiomed.2023.11.044More information about this publication
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Nagenborg, J., Jin, H., Ruder, A. V., Temmerman, L., Mees, B., Schalkwijk, C., Müller-Klieser, D., Berg, T., Goossens, P., Donners, M. M. P. C., & Biessen, E. A. L. (2023). GM-CSF-activated STAT5A regulates macrophage functions and inflammation in atherosclerosis. Frontiers in Immunology, 14, Article 1165306. https://doi.org/10.3389/fimmu.2023.1165306More information about this publication
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Ruder, A., Wetzels, S. M. W., Temmerman, L., Biessen, E. A. L., & Goossens, P. (2023). Monocyte heterogeneity in cardiovascular disease. Cardiovascular Research, 119(11), 2033-2045. https://doi.org/10.1093/cvr/cvad069More information about this publication
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van Kuijk, K., McCracken, I. R., Tillie, R. J. H. A., Asselberghs, S. E. J., Kheder, D. A., Muitjens, S., Jin, H., Taylor, R. S., Schreur, R. W., Kuppe, C., Dobie, R., Ramachandran, P., Gijbels, M. J., Temmerman, L., Kirkwoord, P. M., Luyten, J., Li, Y. M., Noels, H., Goossens, P., ... Sluimer, J. C. (2023). Human and murine fibroblast single-cell transcriptomics reveals fibroblast clusters are differentially affected by ageing and serum cholesterol. Cardiovascular Research, 119(7), 1509-1523. https://doi.org/10.1093/cvr/cvad016More information about this publication
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Ruder, A. V., Temmerman, L., van Dommelen, J. M. A., Nagenborg, J., Lu, C., Sluimer, J. C., Goossens, P., & Biessen, E. A. L. (2023). Culture density influences the functional phenotype of human macrophages. Frontiers in Immunology, 14(1), Article 1078591. https://doi.org/10.3389/fimmu.2023.1078591More information about this publication