A.I. Casas Guijarro

Recent publications

Sedding, D., Schmidt, T. M., Bähre, H., Bavendiek, U., Casas, A. I., Chen, S., Thao-Vi Dao, V., Elbatreek, M. H., Gutzki, F., Hahn, A., Kleikers, P., Krahn, T., Macchiusi, C., Martin, C., Mucke, H., Nogales, C., Schmidt, B. M. L., Seifert, R., Sonnenschein, K., ... Schmidt, H. H. H. W. (2025). Nutritional L-Citrulline and Tetrahydrobiopterin in Peripheral Artery Disease: A Phase II Randomized Trial (CIPER Study). JACC: Advances, 4(3), Article 101590. https://doi.org/10.1016/j.jacadv.2025.101590
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Grønning, A. G., Vonhof, S. E., Elbatreek, M., Hamker, A., Szepanowski, R. D., Erkelenz, S. C., Langhauser, F., Egea, J., Lopez, M. G., Baumbach, J., Kleinschnitz, C., & Casas, A. I. (2025). Unveiling the interplay between soluble guanylate cyclase activation and redox signalling in stroke pathophysiology and treatment. Biomedicine & Pharmacotherapy, 183, Article 117829. https://doi.org/10.1016/j.biopha.2025.117829
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Haupeltshofer, S., Mencl, S., Szepanowski, R. D., Hansmann, C., Casas, A. I., Abberger, H., Hansen, W., Blusch, A., Deuschl, C., Forsting, M., Hermann, D. M., Langhauser, F., & Kleinschnitz, C. (2024). Delayed plasma kallikrein inhibition fosters post-stroke recovery by reducing thrombo-inflammation. Journal of Neuroinflammation, 21(1), Article 155. https://doi.org/10.1186/s12974-024-03149-w
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Maier, A., Rafiei, M., Anastasi, E., Zolotareva, O., Skelton, J., Elkjaer, M. L., Casas, A. I., Nogales, C., Schmidt, H. H. H. W., Kacprowski, T., Blumenthal, D. B., Wipat, A., Sadegh, S., & Baumbach, J. (2024). NeDRex-Web: An Interactive Web Tool for Drug Repurposing by Exploring Heterogeneous Molecular Networks. In M. Cannataro, H. Zheng, L. Gao, J. Cheng, J. L. de Miranda, E. Zumpano, X. Hu, Y.-R. Cho, & T. Park (Eds.), Proceedings - 2024 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2024 (pp. 429-434). IEEE. https://doi.org/10.1109/BIBM62325.2024.10822390
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Pacheco Pachado, M., Casas, A. I., Elbatreek, M. H., Nogales, C., Guney, E., Espay, A. J., & Schmidt, H. H. H. W. (2023). Re-Addressing Dementia by Network Medicine and Mechanism-Based Molecular Endotypes. Journal of Alzheimer's Disease, 96(1), 47-56. Article 230694. https://doi.org/10.3233/JAD-230694
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Palomino-Antolín, A., Decouty-Pérez, C., Farré-Alins, V., Narros-Fernández, P., Lopez-Rodriguez, A. B., Álvarez-Rubal, M., Valencia, I., López-Muñoz, F., Ramos, E., Cuadrado, A., Casas, A. I., Romero, A., & Egea, J. (2023). Redox Regulation of Microglial Inflammatory Response: Fine Control of NLRP3 Inflammasome through Nrf2 and NOX4. Antioxidants, 12(9), Article 1729. https://doi.org/10.3390/antiox12091729
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Szepanowski, R. D., Haupeltshofer, S., Vonhof, S. E., Frank, B., Kleinschnitz, C., & Casas, A. (2023). Thromboinflammatory challenges in stroke pathophysiology. Seminars in Immunopathology, 45(3), 389-410. https://doi.org/10.1007/s00281-023-00994-4
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Petraina, A., Elbatreek, M., Neullens, C. T., Saridaki, T., Dao, V. T.-V., Casas Guijarro, A., & Schmidt, H. (2023). Understanding (apo-) soluble guanylate cyclase allosterism and its therapeutic implications. DrugRxiv. https://doi.org/10.14293/S2199-1006.1.SOR-.PPW9FFL.v2
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Mohamed Mamdouh Abdelkareem Gomaa, Z., Anastasi, E., Hassan, A., Boltze, J., Elbatreek, M., Nogales Calvo, C., Pacheco Pachado, M., Petraina, A., Piper, Z., Rodriguez Gonzalez, A., Wipat, A., Silverman, E., Casas Guijarro, A., Guney, E., Schmidt, H., REPO-TRIAL, & REPO4EU consortia (2023). Why the way we define diseases prevents innovation and precision medicine. DrugRxiv. https://doi.org/10.14293/S2199-1006.1.SOR-.PPCFYDY.v1
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Petraina, A., Elbatreek, M., Neullens, C. T., Saridaki, T., Dao, V. T.-V., Casas Guijarro, A., & Schmidt, H. (2023). On a revised pharmacology of apo-soluble guanylate cyclase and its therapeutic implications. DrugRxiv. https://doi.org/10.14293/S2199-1006.1.SOR-.PPW9FFL.v1
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