Prof Dr Tilman Hackeng (T.M.)

Urlings, E. H., Heubel-Moenen, F. C. J. I., van Oerle, R., Hellenbrand, D. L. S., van der Meijden, P. E. J., Hackeng, T. M., Cate, H. T., Nagy, M., Henskens, Y. M. C., & Spronk, H. M. H. (2026). Intrinsic activated thrombin generation for treatment efficacy and monitoring of octocog alfa and emicizumab in severe hemophilia A. Research and practice in thrombosis and haemostasis, 10(4), Article 106627. https://doi.org/10.1016/j.rpth.2026.106627

Biguzzi, E., Winckers, K., Hackeng, T. M., Rosendaal, F. R., & Vlieg, A. V. H. (2026). Recurrent venous thromboembolism: association with thrombin generation and d-dimer. Research and practice in thrombosis and haemostasis, 10(2), Article 103391. https://doi.org/10.1016/j.rpth.2026.103391

Auditeau, C., Bianchini, E. P., Peyron, I., Ruty, A., Saenjamsai, P., Khamari, M., Hackeng, T. M., Christophe, O. D., Denis, C. V., Borgel, D., Lenting, P. J., & Saller, F. (2026). Anti-TFPI Single-Domain Antibodies: Novel Rebalancing Therapies for Hemophilia and Other Rare Bleeding Disorders. Thrombosis and Haemostasis. Advance online publication. https://doi.org/10.1055/a-2894-0856

Xin, X., Dijkgraaf, I., Hackeng, T. M., & Koenen, R. R. (2025). Generation and characterization of platelet-derived extracellular vesicle analogues from lyophilized platelets. Extracellular Vesicle, 6, Article 100095. https://doi.org/10.1016/j.vesic.2025.100095

Obino, G., Nieddu, G., Nagy, M., Ippel, H., Cubeddu, T., Spronk, H. M. H., Hackeng, T. M., Formato, M., Lepedda, A. J., & Moroni, L. (2025). Marine-derived sulfated polysaccharides enhance hemocompatibility and endothelialization of nanofibrous PCL for vascular graft applications. Cell Biomaterials, 1(10), Article 100155. https://doi.org/10.1016/j.celbio.2025.100155

Denisov, S. S., Bialek, E. L., Beretta, F., Smagurauskaite, G., Ippel, H., Fijlstra, E., Kale, S. S., Timmerman, P., Hackeng, T. M., Proost, P., Goldflam, M., & Dijkgraaf, I. (2025). Chemokine-Binding All-D-CLIPS Peptides Identified Using Mirror-Image Phage Display. ACS Chemical Biology, 20(11), 2798-2807. https://doi.org/10.1021/acschembio.5c00726

Ippel, H., Peijnenborgh, S. J., Hackeng, T. M., & Agten, S. M. (2025). Calcium binding by γ-carboxyglutamic acid: it takes two to tether. Research and practice in thrombosis and haemostasis, 9(5), Article 102964. https://doi.org/10.1016/j.rpth.2025.102964

Winckers, K., Biguzzi, E., Thomassen, S., Heinzmann, A., Rosendaal, F. R., Hackeng, T. M., & van Hylckama-Vlieg, A. (2025). Risk of First Venous Thrombosis by Comparing Different Thrombin Generation Assay Conditions: Results from the MEGA Case-control Study. TH open : companion journal to thrombosis and haemostasis, 9, Article a25346123. https://doi.org/10.1055/a-2534-6123

Bouwens, B. R. C., Magdeleyns, E., Thomassen, M. C. L. G. D., Bouwman, F. G., Suylen, D. P., Hackeng, T. M., & Koenen, R. R. (2025). Citrullination of tissue factor pathway inhibitor alpha by peptidylarginine deiminase 4 impairs its natural anticoagulant activity toward factors Xa and VIIa/tissue factor and reduces binding to its cofactor protein S. Journal of Thrombosis and Haemostasis, 23(2), 641-650. https://doi.org/10.1016/j.jtha.2024.11.009

Gentier, A., Aizaz, M., Halder, M., Florea, A., Dijkgraaf, I., Mottaghy, F. M., Hackeng, T., & Kooi, M. E. (2024). Why Current Detection of Vascular Calcification Falls Short and How to Improve on It. TH open : companion journal to thrombosis and haemostasis, 08(04), e340-e349. https://doi.org/10.1055/a-2495-1444