Prof Dr Tilman Hackeng (T.M.)
Recent publications
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Biguzzi, E., Winckers, K., Hackeng, T. M., Rosendaal, F. R., & Vlieg, A. V. H. (2026). Recurrent venous thromboembolism: association with thrombin generation and d-dimer. Research and practice in thrombosis and haemostasis, 10(2), Article 103391. https://doi.org/10.1016/j.rpth.2026.103391More information about this publication
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Xin, X., Dijkgraaf, I., Hackeng, T. M., & Koenen, R. R. (2025). Generation and characterization of platelet-derived extracellular vesicle analogues from lyophilized platelets. Extracellular Vesicle, 6, Article 100095. https://doi.org/10.1016/j.vesic.2025.100095More information about this publication
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Obino, G., Nieddu, G., Nagy, M., Ippel, H., Cubeddu, T., Spronk, H. M. H., Hackeng, T. M., Formato, M., Lepedda, A. J., & Moroni, L. (2025). Marine-derived sulfated polysaccharides enhance hemocompatibility and endothelialization of nanofibrous PCL for vascular graft applications. Cell Biomaterials, 1(10), Article 100155. https://doi.org/10.1016/j.celbio.2025.100155More information about this publication
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Denisov, S. S., Bialek, E. L., Beretta, F., Smagurauskaite, G., Ippel, H., Fijlstra, E., Kale, S. S., Timmerman, P., Hackeng, T. M., Proost, P., Goldflam, M., & Dijkgraaf, I. (2025). Chemokine-Binding All-D-CLIPS Peptides Identified Using Mirror-Image Phage Display. ACS Chemical Biology, 20(11), 2798-2807. https://doi.org/10.1021/acschembio.5c00726More information about this publication
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Ippel, H., Peijnenborgh, S. J., Hackeng, T. M., & Agten, S. M. (2025). Calcium binding by γ-carboxyglutamic acid: it takes two to tether. Research and practice in thrombosis and haemostasis, 9(5), Article 102964. https://doi.org/10.1016/j.rpth.2025.102964More information about this publication
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Winckers, K., Biguzzi, E., Thomassen, S., Heinzmann, A., Rosendaal, F. R., Hackeng, T. M., & van Hylckama-Vlieg, A. (2025). Risk of First Venous Thrombosis by Comparing Different Thrombin Generation Assay Conditions: Results from the MEGA Case-control Study. TH open : companion journal to thrombosis and haemostasis, 09, Article a25346123. Advance online publication. https://doi.org/10.1055/a-2534-6123More information about this publication
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Bouwens, B. R. C., Magdeleyns, E., Thomassen, M. C. L. G. D., Bouwman, F. G., Suylen, D. P., Hackeng, T. M., & Koenen, R. R. (2025). Citrullination of tissue factor pathway inhibitor alpha by peptidylarginine deiminase 4 impairs its natural anticoagulant activity toward factors Xa and VIIa/tissue factor and reduces binding to its cofactor protein S. Journal of Thrombosis and Haemostasis, 23(2), 641-650. https://doi.org/10.1016/j.jtha.2024.11.009More information about this publication
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Gentier, A., Aizaz, M., Halder, M., Florea, A., Dijkgraaf, I., Mottaghy, F. M., Hackeng, T., & Kooi, M. E. (2024). Why Current Detection of Vascular Calcification Falls Short and How to Improve on It. TH open : companion journal to thrombosis and haemostasis, 08(04), e340-e349. https://doi.org/10.1055/a-2495-1444More information about this publication
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Vroemen, W. H. M., Denessen, E. J. S., van Doorn, W. P. T. M., Pelzer, K. E. J. M., Hackeng, T. M., Litjens, E. J. R., Henskens, Y. M. C., van der Sande, F. M., Wodzig, W. K. W. H., Kooman, J. P., Bekers, O., de Boer, D., & Mingels, A. M. A. (2024). Differences in Cardiac Troponin T Composition in Myocardial Infarction and End-Stage Renal Disease Patients: A Blood Tube Effect? Journal of Applied Laboratory Medicine, 9(5), 989-1000. https://doi.org/10.1093/jalm/jfae052More information about this publication
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Schreuder, M., Jourdi, G., Veizaj, D., Poole, D. A., Cheung, K. L., Poenou, G., Verhoef, D., Thomassen, S., Janssen, L. F. H., Stepanian, A., Hackeng, T. M., Gaussem, P., Reitsma, P. H., Geerke, D. P., Siguret, V., & Bos, M. H. A. (2024). Minimally Modified Human Blood Coagulation Factor X to Bypass Direct Factor Xa Inhibitors. Journal of Thrombosis and Haemostasis, 22(8), 2211-2226. https://doi.org/10.1016/j.jtha.2024.04.022More information about this publication