Prof Dr Tilman Hackeng (T.M.)

Dr Tilman M Hackeng studied Biochemistry at the University of Utrecht, where he obtained his PhD in 1993. He then became a postdoctoral fellow and senior researcher at The Scripps Research Institute in La Jolla USA before returning to the Netherlands as a Royal Netherlands Academy of Arts and Sciences Fellow at Maastricht University in 1998. 

Dr Hackeng is professor and past chair of the Department of Biochemistry at Maastricht University and past chair of the Netherlands Society on Thrombosis and Haemostasis (NVTH). He is actively involved with the International Society on Thrombosis and Haemostasis (ISTH) and is a co-founder and organiser of the European Congress on Thrombosis and Haemostasis (ECTH). He is chairman of the Scientific Advisory Board of the Dutch Thrombosis Foundation and he is elected member of the Royal Netherlands Society of Sciences and Humanities. Currently, he is director of Maastricht University’s Cardiovascular Research Institute (CARIM).

Dr Hackeng’s research programme investigates the role of blood coagulation proteins in thrombosis and cardiovascular disease, with an emphasis on anticoagulant regulatory pathways and the regulation of thrombin formation. Using a multidisciplinary approach, the programme employs structure-function analysis of coagulation proteins and the development of clinical assays to screen for functional impairments in proteins in patients with thrombosis. Additionally, his research includes chemical protein synthesis for applications in thrombosis and haemostasis, cancer, targeted molecular imaging, and synthetic vaccines, utilising technologies such as SPPS, native chemical ligation, and multimodal constructs for advanced molecular imaging and therapeutic applications.