R.C.J. Langen

Wanders, N., Martens, M., Kelders, M., Manse, S., van Krimpen, S., Groenen, C., Kapsali, C., Bilbao Fraile, P., Bermperi, K., Boumans, N., Ahidar, Y., Dubois, L., Smeets, H., van de Worp, W., & Langen, R. (2026). The Secretome of a Cachexia-Inducing Lung Tumor Impairs Mitochondrial Function and Skeletal Muscle Differentiation. Cancers, 18(13), Article 2130. https://doi.org/10.3390/cancers18132130

Sarc, I., Langen, R., Gosker, HR., & Lainscak, M. (2026). Calprotectin and Sarcopenia in COPD: Biomarker, Bystander or Target? Journal of cachexia, sarcopenia and muscle, 17(2), Article e70283. https://doi.org/10.1002/jcsm.70283

Westheim, A. J. F., Dubois, L. J., Prades-Sagarra, E., Chan, J., van der Wiel, A. M. A., Lieuwes, N. G., Biemans, R., Cong, Y., Houben, T., Meesters, D. M., Yaromina, A., van Dijk, M., van Bergenhenegouwen, J., van Helvoort, A., Langen, R. C. J., Penders, J., Shiri-sverdlov, R., & Theys, J. (2026). The Effect of Dietary Fiber Compositions on the Therapeutic Outcome of Combined Radio- and Immunotherapy in a Preclinical Cancer Model. Molecular Nutrition & Food Research, 70(2), Article e70370. https://doi.org/10.1002/mnfr.70370

van Krimpen, S. J., Simons, S. O., Schols, A. M. W. J., Langen, R. C. J., & Gosker, H. R. (2026). Glucocorticoid-induced muscle weakness in ECOPD: a perspective on mechanisms and emerging pharmacological interventions. Expert Review of Respiratory Medicine, 20(7), 859-871. https://doi.org/10.1080/17476348.2026.2620144

van Iersel, L. E. J., Pelgrim, C. E., Kraneveld, A. D., van Ark, I., van Helvoort, A., Kelders, M. C. J. M., Langen, R. C. J., Beijers, R. J. H. C. G., Schols, A. M. W. J., & Gosker, H. R. (2025). Nutritional modulation of skeletal muscle weakness in an experimental model of repetitive COPD exacerbations. Heliyon, 11(9), Article e43331. https://doi.org/10.1016/j.heliyon.2025.e43331

Westheim, A. J. F., Dubois, L. J., Prades-Sagarra, E., van de Laak, J. G. M., van Mourik, H., Schuitmaker, L., Stoffels, L. M., Yaromina, A., van Dijk, M., van Bergenhenegouwen, J., van Helvoort, A., Langen, R. C. J., Shiri-Sverdlov, R., & Theys, J. (2025). Dietary enrichment with n-3 lc-PUFA-rich fish oil improves preclinical outcome of radiotherapy and anti-PD-L1 combination treatment. Cancer Treatment and Research Communications, 44, Article 100943. https://doi.org/10.1016/j.ctarc.2025.100943

van de Worp, W. R. P. H., Theys, J., Wolfs, C. J. A., Verhaegen, F., Schols, A. M. W. J., van Helvoort, A., & Langen, R. C. J. (2024). Targeted nutritional intervention attenuates experimental lung cancer cachexia. Journal of cachexia, sarcopenia and muscle, 15(5), 1664-1676. https://doi.org/10.1002/jcsm.13520

Betz, M. W., De Brandt, J., Aussieker, T., Monsegue, A. P., Houtvast, D. C. J., Gehlert, S., Verdijk, L. B., van Loon, L. J. C., Gosker, H. R., Langen, R. J. C., Derave, W., Burtin, C., Spruit, M. A., & Snijders, T. (2024). Muscle fibre satellite cells are located at a greater distance from capillaries in patients with COPD compared with healthy controls. ERJ Open Research, 10(5), Article 00203-2024. https://doi.org/10.1183/23120541.00203-2024

Daenen, L. H. B. A., van de Worp, W. R. P. H., Rezaeifar, B., de Bruijn, J., Qiu, P., Webster, J. M., Peeters, S., de Ruysscher, D., Langen, R. C. J., Wolfs, C. J. A., & Verhaegen, F. (2024). Towards a fully automatic workflow for investigating the dynamics of lung cancer cachexia during radiotherapy using cone beam computed tomography. Physics in Medicine and Biology, 69(20), Article 205005. https://doi.org/10.1088/1361-6560/ad7d5b

Bartolomeo, V., Jongbloed, M., van de Worp, W. R. P. H., Langen, R., Degens, J., Hendriks, L. E. L., & de Ruysscher, D. K. M. (2024). Cachexia and Sarcopenia in Oligometastatic Non-Small Cell Lung Cancer: Making a Potential Curable Disease Incurable? Cancers, 16(1), Article 230. https://doi.org/10.3390/cancers16010230