Research

MaCSBio strives to perform cutting edge research in the interdisciplinary field of Systems Biology to create a “Digital Twin”, a set of computational and mathematical models based on biological evidence that will help to understand and predict human systems. Research projects at MaCSBio focus on modelling across multiple scales of time and space, tackling areas that are highly relevant for society:

Systems BioMedicine

Projects within this theme aim to increase our understanding of chronic diseases related to metabolism, such as obesity, diabetes, heart failure, ageing and immune function, and to develop new, biology-based, personalised approaches to prevent and treat them.

Computational Neuroscience

Projects within this theme aim at better understanding brain function and pathologies, from genes to organelles and cells, and from local networks to the whole organ.

Plant Systems Biology

Projects within this theme aim to increase our understanding of plant physiology and development, including plant-microbe interactions, heat stress tolerance and growth regulation.