MosaBiome
Research department
MosaBiome is the microbiome research facility of Maastricht University/Maastricht UMC+ at the Department of Medical Microbiology, Infectious Diseases, and Infection Prevention (MMI).
As a non-profit group, MosaBiome's mission is to enable, support, and deliver microbiome research for scientists, research consortia, (healthcare) institutions, and industry partners with academic rigour, transparency, and a focus on research needs rather than commercial priorities.
Our Services
Support for Grant Applications
- Guidance in designing microbiome components for grant proposals
- Development of realistic budgets, timelines, and work packages
- Support in crafting study design and analysis plans
Guidance on Optimal Study Design
- Cross-sectional and Longitudinal
Sampling strategy
- Sample size
- Relevant covariates and confounding factors
- Appropriate controls and replicates
Microbiome Sequencing
Methods:
- 16S and ITS rRNA Gene Amplicon Sequencing
- Shotgun Metagenomic Sequencing
Platforms:
- Illumina MiSeq
- Oxford Nanopore
Statistical Analysis
- Microbiome-appropriate analysis methods for cross-sectional, longitudinal, and multivariate analysis
- Confounding factors assessment and compositionality-aware techniques
- Clear interpretation and reporting of results
Clinical & Biological Relevance
- Identification of biologically meaningful patterns and associations
- Support in translating findings into actionable insights
Bioinformatic Processing
- Standardised pipelines for QC, denoising, taxonomic profiling, and functional annotation
- Transparent, reproducible workflows ensuring traceability
Delivery of clean, analysis-ready datasets
Support for Academic Publication
- Preparation of publication-ready figures, tables, and methods
- Ensuring reproducibility and compliance with journal standards and FAIR principles
