P.J.A. Leenders

Manukjan, N., Majcher, D., Leenders, P., Caiment, F., van Herwijnen, M., Smeets, H. J. J., Suidgeest, E., van der Weerd, L., Vanmierlo, T., Jansen, J. F. A., Backes, W. H. H., van Oostenbrugge, R. J. J., Staals, J., Fulton, D., Ahmed, Z., Blankesteijn, W. M., & Foulquier, S. (2023). Hypoxic oligodendrocyte precursor cell-derived VEGFA is associated with blood-brain barrier impairment. Acta neuropathologica communications, 11(1), Article 128. https://doi.org/10.1186/s40478-023-01627-5

Kerkhofs, D., Helgers, R., Hermes, D., Steinbusch, H. P. J., Van Essen, H., Leenders, P., Prickaerts, J., Staals, J., Biessen, E. A., Van Oostenbrugge, R. J., & Foulquier, S. (2023). Amlodipine limits microglia activation and cognitive dysfunction in aged hypertensive mice. Journal of Hypertension, 41(7), 1159-1167. https://doi.org/10.1097/HJH.0000000000003445

Neradova, A., Wasilewski, G., Prisco, S., Leenders, P., Caron, M., Welting, T., van Rietbergen, B., Kramann, R., Floege, J., Vervloet, M. G., & Schurgers, L. J. (2022). Combining phosphate binder therapy with vitamin K2 inhibits vascular calcification in an experimental animal model of kidney failure. Nephrology Dialysis Transplantation, 37(4), 652-662. https://doi.org/10.1093/ndt/gfab314

van Gorp, R. H., Baaten, C. C. F. M. J., Habibi, A., Jaminon, A. M. G., Peeters, F. E. C. M., Leenders, P., Crijns, H. J. G. M. C., Heemskerk, J. W. M., Reutelingsperger, C. P., Spronk, H. M., & Schurgers, L. J. (2021). Vitamin K antagonist use induces calcification and atherosclerotic plaque progression resulting in increased hypercoagulability. European heart journal open, 1(2), Article oeab017. https://doi.org/10.1093/ehjopen/oeab017

van Gorp, R. H., Dijkgraaf, I., Bröker, V., Bauwens, M., Leenders, P., Jennen, D., Dweck, M. R., Bucerius, J., Briedé, J. J., van Ryn, J., Brandenburg, V., Mottaghy, F., Spronk, H. M. H., Reutelingsperger, C. P., & Schurgers, L. J. (2021). Off-target effects of oral anticoagulants - vascular effects of vitamin K antagonist and non-vitamin K antagonist oral anticoagulant dabigatran etexilate. Journal of Thrombosis and Haemostasis, 19(5), 1348-1363. https://doi.org/10.1111/jth.15289

Mastenbroek, T. G., Karel, M. F. A., Nagy, M., Chayoua, W., Korsten, E. I. J., Coenen, D. M., Debets, J., Konings, J., Brouns, A. E., Leenders, P. J. A., van Essen, H., van Oerle, R., Heitmeier, S., Spronk, H. M., Kuijpers, M. J. E., & Cosemans, J. M. E. M. (2020). Vascular protective effect of aspirin and rivaroxaban upon endothelial denudation of the mouse carotid artery. Scientific Reports, 10(1), Article 19360. https://doi.org/10.1038/s41598-020-76377-8

Daskalopoulos, E. P., Hermans, K. C. M., Debets, J., Strzelecka, A., Leenders, P., Vervoort-Peters, L., Janssen, B. J. A., & Blankesteijn, W. M. (2019). The Beneficial Effects of UM206 on Wound Healing After Myocardial Infarction in Mice Are Lost in Follow-Up Experiments. Frontiers in Cardiovascular Medicine, 6, Article 118. https://doi.org/10.3389/fcvm.2019.00118

Posthuma, J. J., Posma, J. J. N., van Oerle, R., Leenders, P., van Gorp, R. H., Jaminon, A. M. G., Mackman, N., Heitmeier, S., Schurgers, L. J., ten Cate, H., & Spronk, H. M. H. (2019). Targeting Coagulation Factor Xa Promotes Regression of Advanced Atherosclerosis in Apolipoprotein-E Deficient Mice. Scientific Reports, 9(1), Article 3909. https://doi.org/10.1038/s41598-019-40602-w

Borissoff, J. I., Otten, J. J. T., Heeneman, S., Leenders, P., van Oerle, R., Soehnlein, O., Loubele, S. T. B. G., Hamulyak, K., Hackeng, T. M., Daemen, M. J. A. P., Degen, J. L., Weiler, H., Esmon, C. T., van Ryn, J., Biessen, E. A. L., Spronk, H. M. H., & ten Cate, H. (2013). Genetic and Pharmacological Modifications of Thrombin Formation in Apolipoprotein E-deficient Mice Determine Atherosclerosis Severity and Atherothrombosis Onset in a Neutrophil-Dependent Manner. PLOS ONE, 8(2), Article e55784. https://doi.org/10.1371/journal.pone.0055784

Dargaud, Y., Spronk, H. M. H., Leenders, P., Hemker, H. C., & Ten Cate, H. (2010). Monitoring platelet dependent thrombin generation in mice. Thrombosis Research, 126(5), 436-441. https://doi.org/10.1016/j.thromres.2010.08.007