K.R. Kampen
Recent publications
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Schuitmaker, L., van der Wiel, A. M. A., Lieuwes, N. G., Biemans, R., Mutsters, N. A. M., Jung, J., Bastos, V. C., Sagarra, E. P., Kuang, S., Setton, J., Langie, S. A. S., Kampen, K. R., Theys, J., Yaromina, A., Dubois, L. J., & Lambin, P. (2026). Deficiencies in the Fanconi anemia or homologous recombination pathway enhance the antitumor effects of the hypoxia-activated prodrug CP-506. Molecular Therapy: Oncology, 34(1), Article 201161. https://doi.org/10.1016/j.omton.2026.201161More information about this publication
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Pepe, D., Janssens, X., Timcheva, K., Marrón-Liñares, G. M., Verbelen, B., Konstantakos, V., De Groote, D., De Bie, J., Verhasselt, A., Dewaele, B., Godderis, A., Cools, C., Franco-Tolsau, M., Royaert, J., Verbeeck, J., Kampen, K. R., Subramanian, K., Cabrerizo Granados, D., Menschaert, G., & De Keersmaecker, K. (2025). Reannotation of cancer mutations based on expressed RNA transcripts reveals functional non-coding mutations in melanoma. American Journal of Human Genetics, 112(6), 1447-1467. https://doi.org/10.1016/j.ajhg.2025.04.005More information about this publication
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Sanchez-Castillo, A., Savelkouls, K. G., Baldini, A., Hounjet, J., Sonveaux, P., Verstraete, P., De Keersmaecker, K., Dewaele, B., Bjorkblom, B., Melin, B., Wu, W. Y., Sjoberg, R. L., Rouschop, K. M. A., Broen, M. P. G., Vooijs, M., & Kampen, K. R. (2024). Sertraline/chloroquine combination therapy to target hypoxic and immunosuppressive serine/glycine synthesis-dependent glioblastomas. Oncogenesis, 13(1), Article 39. https://doi.org/10.1038/s41389-024-00540-3More information about this publication
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Sanchez-Castillo, A., & Kampen, K. R. (2024). Understanding serine and glycine metabolism in cancer: a path towards precision medicine to improve patient's outcomes. Discover. Oncology, 15(1), Article 652. https://doi.org/10.1007/s12672-024-01544-6More information about this publication
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Beaumont, J. E. J., Barbeau, L. M. O., Ju, J., Savelkouls, K. G., Bouwman, F. G., Zonneveld, M. I., Bronckaers, A., Kampen, K. R., Keulers, T. G. H., & Rouschop, K. M. A. (2024). Cancer EV stimulate endothelial glycolysis to fuel protein synthesis via mTOR and AMPKα activation. Journal of Extracellular Vesicles, 13(7), Article e12449. https://doi.org/10.1002/jev2.12449More information about this publication
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Hounjet, J., Van Aerschot, L., De Keersmaecker, K., Vooijs, M., & Kampen, K. R. (2024). The DMT1 isoform lacking the iron-response element regulates normal and malignant hematopoiesis via NOTCH pathway activation. Febs Letters, 598(12), 1506-1512. https://doi.org/10.1002/1873-3468.14870More information about this publication
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Sánchez-Castillo, A., Heylen, E., Hounjet, J., Savelkouls, K. G., Lieuwes, N. G., Biemans, R., Dubois, L. J., Reynders, K., Rouschop, K. M., Vaes, R. D. W., De Keersmaecker, K., Lambrecht, M., Hendriks, L. E. L., De Ruysscher, D. K. M., Vooijs, M., & Kampen, K. R. (2024). Correction: Targeting serine/glycine metabolism improves radiotherapy response in non-small cell lung cancer. British Journal of Cancer, 130(4), Article 701. https://doi.org/10.1038/s41416-024-02603-zMore information about this publication
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Sanchez-Castillo, A., Heylen, E., Hounjet, J., Savelkouls, K. G., Lieuwes, N. G., Biemans, R., Dubois, L. J., Reynders, K., Rouschop, K. M., Vaes, R. D. W., De Keersmaecker, K., Lambrecht, M., Hendriks, L. E. L., De Ruysscher, D. K. M., Vooijs, M., & Kampen, K. R. (2024). Targeting serine/glycine metabolism improves radiotherapy response in non-small cell lung cancer. British Journal of Cancer, 130(4), 568-584. https://doi.org/10.1038/s41416-023-02553-yMore information about this publication
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Hounjet, J., Groot, A. J., Piepers, J. P., Kranenburg, O., Zwijnenburg, D. A., Rapino, F. A., Koster, J. B., Kampen, K. R., & Vooijs, M. A. (2023). Iron-responsive element of Divalent metal transporter 1 (Dmt1) controls Notch-mediated cell fates. The FEBS journal, 290(24), 5811-5834. https://doi.org/10.1111/febs.16946More information about this publication
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Verstraete, P., De Keersmaecker, K., & Kampen, K. R. (2023). Drivers of de novo Serine/Glycine synthesis in acute leukemia. Febs Letters, 597(17), 2145-2146. https://doi.org/10.1002/1873-3468.14700More information about this publication