D.H.J. Theunissen, MSc

Recent publications

• van Breda, S. G. J., Claessen, S. M. H., van Herwijnen, M., Theunissen, D. H. J., Jennen, D. G. J., de Kok, T. M. C. M., & Kleinjans, J. C. S. (2018). Integrative omics data analyses of repeated dose toxicity of valproic acid in vitro reveal new mechanisms of steatosis induction. Toxicology, 393, 160-170. https://doi.org/10.1016/j.tox.2017.11.013

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• Hebels, D. G. A. J., Carlier, A., Coonen, M. L. J., Theunissen, D. H., & de Boer, J. (2017). cBiT: A transcriptomics database for innovative biomaterial engineering. Biomaterials, 149, 88-97. https://doi.org/10.1016/j.biomaterials.2017.10.008

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• Wolters, J. E. J., van Herwijnen, M. H. M., Theunissen, D. H. J., Jennen, D. G. J., Van den Hof, W. F. P. M., de Kok, T., Schaap, F. G., van Breda, S. G. J., & Kleinjans, J. C. S. (2016). Integrative "-Omics" Analysis in Primary Human Hepatocytes Unravels Persistent Mechanisms of Cyclosporine A-Induced Cholestasis. Chemical Research in Toxicology, 29(12), 2164-2174. https://doi.org/10.1021/acs.chemrestox.6b00337

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• Deferme, L., Wolters, J. E. J., Claessen, S. M. H., Theunissen, D., van den Beucken, T., Wagner, J. R., van Breda, S. G., Kleinjans, J. C. S., & Briede, J. J. (2016). Dynamic Interplay between the Transcriptome and Methylome in Response to Oxidative and Alkylating Stress. Chemical Research in Toxicology, 29(9), 1428-1438. https://doi.org/10.1021/acs.chemrestox.6b00090

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• Rieswijk, L., Claessen, S. M. H., Bekers, O., van Herwijnen, M., Theunissen, D. H. J., Jennen, D. G. J., de Kok, T., Kleinjans, J. C. S., & van Breda, S. G. J. (2016). Aflatoxin B1 induces persistent epigenomic effects in primary human hepatocytes associated with hepatocellular carcinoma. Toxicology, 350, 31-39. https://doi.org/10.1016/j.tox.2016.05.002

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• van Breda, S. G. J., Claessen, S. M. H., Lo, K., van Herwijnen, M., Brauers, K. J. J., Lisanti, S., Theunissen, D. H. J., Jennen, D. G. J., Gaj, S., de Kok, T., & Kleinjans, J. C. S. (2015). Epigenetic mechanisms underlying arsenic-associated lung carcinogenesis. Archives of Toxicology, 89(11), 1959-1969. https://doi.org/10.1007/s00204-014-1351-2

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• Coonen, M. L. J., Theunissen, D., Kleinjans, J. C. S., & Jennen, D. G. J. (2015). MagiCMicroRna: a web implementation of AgiMicroRna using shiny. Source code for biology and medicine, 10(1), Article 4. https://doi.org/10.1186/s13029-015-0035-5

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• Hebels, D. G. A., Jetten, M. J. A., Aerts, H. J. W., Herwig, R., Theunissen, D. H. J., Gaj, S., van Delft, J. H., & Kleinjans, J. C. S. (2014). Evaluation of database-derived pathway development for enabling biomarker discovery for hepatotoxicity. Biomarkers in Medicine, 8(2), 185-200. https://doi.org/10.2217/bmm.13.154

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