W.H. Backes

Verstappen, D., de Jong, J. J. A., Voorter, P. H. M., van Dinther, M., van Oostenbrugge, R. J., Staals, J., Jansen, J. F. A., & Backes, W. H. (2025). DCE-MRI reveals spatial pattern in heterogeneous blood-brain barrier leakage within white matter in cerebral small vessel disease. Journal of Cerebral Blood Flow and Metabolism, 45(11), 2104-2114. Article 0271678X251364151. https://doi.org/10.1177/0271678X251364151

Voorter, P. H. M., van Dinther, M., Drenthen, G. S., Elschot, E. P., Staals, J., van Oostenbrugge, R. J., Jansen, J. F. A., & Backes, W. H. (2025). Vessel architecture imaging reveals microvascular rarefaction and capillary-to-arteriole shift in cerebral small vessel disease. Journal of Cerebral Blood Flow and Metabolism, 45(11), 2092-2103. https://doi.org/10.1177/0271678X251358968

van der Heide, F. C. T., Steens, I. L. M., Singh-Manoux, A., Sabia, S., Zhou, T. L., Kohler, S., Schram, M. T., van der Kallen, C. J. H., Berendschot, T. T. J. M., Webers, C. A. B., van Greevenbroek, M. M. J., Wesselius, A., Arts, I. C. W., Jansen, J. F. A., Backes, W. H., van Sloten, T. T., Blokland, G. A. M., & Stehouwer, C. D. A. (2025). Genetic variation in the glucagon-like peptide-1 receptor protein encoding region is associated with higher heart rate variability, but not with neurodegeneration of the brain, retina, and peripheral nerves: The Maastricht study. Cardiovascular Diabetology, 24(1), Article 397. https://doi.org/10.1186/s12933-025-02888-1

Backes, W. H., Verstappen, D., de Jong, J. J. A., & Jansen, J. F. A. (2025). Slowly crossing the blood-brain barrier takes time. Alzheimer's & Dementia, 21(10), 2. Article e70687. https://doi.org/10.1002/alz.70687

van Lanen, R. H. G. J., Uher, D., Hoeberigs, C. M. C., Hofman, P. A. M., Santegoeds, R., Wiggins, C., Tse, D. H. Y., Steijvers, E. G. M., Jansen, J. F. A., Drenthen, G. S., Roebroeck, A., Ivanov, D., Poser, B. A., van Kuijk, S. M. J., Hoogland, G., Rijkers, K., Wagner, L. G. L., Widman, G., Beckervordersandforth, J., ... ACE Epilepsy Surgery Group (2025). Value of ultra-high-field MRI in patients with drug-resistant focal epilepsy and negative 3T MRI (EpiUltraStudy): Diagnostic gain of 7T structural analysis. Epilepsia. Advance online publication. https://doi.org/10.1111/epi.18682

van der Meulen, L. R., van Dinther, M., Chiribiri, A., Smink, J., Backes, W. H., Bennett, J., Wildberger, J. E., Scannell, C. M., Holtackers, R. J., & Crucial Investigators (2025). Artificial Intelligence-Based Arterial Input Function for the Quantitative Assessment of Myocardial Blood Flow and Perfusion Reserve in Cardiac Magnetic Resonance: A Validation Study. Diagnostics, 15(18), Article 2341. https://doi.org/10.3390/diagnostics15182341

Alers, R.-J., Ghossein-Doha, C., Brandt, Y., Kooi, M. E., Gerretsen, S. C., Jansen, J. F. A., Backes, W. H., van de Ven, V., Hurks, P. P. M., & Spaanderman, M. E. A. (2025). Associations of Metabolic Syndrome and Insulin Resistance With Attenuated Executive Function Post-Preeclampsia: A Nested Case-Control Study. Bjog-an International Journal of Obstetrics and Gynaecology, 132(9), 1269-1277. https://doi.org/10.1111/1471-0528.18186

Bakker, L., Ramakers, I. H. G. B., Greevenbroek, M. M. J. V., Backes, W. H., Jansen, J. F. A., Schram, M. T., Kallen, C. J. H. V. D., Schalkwijk, C. G., Wesselius, A., Ulvik, A., Ueland, P. M., Verhey, F. R. J., Eussen, S. J. P. M., & Kohler, S. (2025). The kynurenine pathway and markers of neurodegeneration and cerebral small vessel disease: The Maastricht Study. Journal of the Neurological Sciences, 474, Article 123522. https://doi.org/10.1016/j.jns.2025.123522

Uher, D., Drenthen, G. S., Hoeberigs, C. M., van Lanen, R. H. G. J., Colon, A. J., Haast, R. A. M., Kranen-Mastenbroek, V. H. J. M. V., Widman, G., Hofman, P. A. M., Wagner, L. G., Beckervordersandforth, J. C., Jansen, J. F. A., Schijns, O. E. M. G., Backes, W. H., & ACE study group (2025). The role of ultra-high field MRI and image processing in the presurgical workup in MRI-negative focal epilepsy: A validated 7T MRI case study. Epilepsy & Behavior Reports, 30, Article 100761. https://doi.org/10.1016/j.ebr.2025.100761

van der Knaap, N., Klinkhammer, S., Postma, A. A., Visser-Meily, J. M. A., Horn, J., van Heugten, C. M., Voorter, P. H. M., van der Thiel, M. M., Drenthen, G. S., Backes, W. H., van Rosmalen, F., van Santen, S., van Bussel, B. C. T., van der Horst, I. C. C., Linden, D. E. J., Aries, M. J. H., & Jansen, J. F. A. (2025). Post-COVID microvascular dysfunction in hospitalized COVID-19 survivors is associated with acute disease severity and persistent cognitive complaints. Journal of the Neurological Sciences, 472, Article 123464. https://doi.org/10.1016/j.jns.2025.123464