Paul Wieringa (P.A.)
Research profile
The current focus is on the development and application of 3D co-culture environment to combine peripheral neurons (sensory, motor, sympathetic, parasympathetic) with other tissue types in an organized and controlled manner. By incorporating optogenetic control of neural activity, the aim is to create controlled and functionally innervated tissue and to study the impact of neural stimulation on tissue health, disease, and regeneration. The end goal is to answer fundamental biological questions and generate new regenerative medicine strategies.
In addition, peripheral nerve repair remains an active area of research as well as the application of 3D in vitro culture systems for other possible appications.
Key publications
Wieringa, P. A., de Pinho, A. R. G., Micera, S., van Wezel, R. J. A., & Moroni, L. (2018). Biomimetic Architectures for Peripheral Nerve Repair: A Review of Biofabrication Strategies. Advanced Healthcare Materials, 7(8), Article 1701164. https://doi.org/10.1002/adhm.201701164
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