Matthijs Cluitmans (M.J.M.)
Research profile
As a biomedical engineer and medical doctor, Matthijs hopes to bring more insight in the mechanisms of unexplained ventricular arrhythmias which can lead to sudden cardiac death. He currently is executing an NWO Veni grant to clinically characterize, experimentally study and computationally model the mechanisms of trigger-substrate interaction leading to arrhythmias in the ventricles. He is focusing on the role of repolarization abnormalities in that setting and also works for the clinical Vigilance study headed by Prof. Volders.
Matthijs is especially interested in contributing to the personalization of medicine, using computational models to provide insights in arrhythmia mechanisms at the level of an individual rather than at the level of a population of patients. At Maastricht University, his research focuses on the (individual) mechanistic understanding of ventricular arrhythmias. In his part-time position at Philips Research, Matthijs is exploring the use of computational electrophysiology models to personalize diagnosis and therapy. The overlap between these positions promotes the transition from scientific findings to clinical application.
Key publications
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Cluitmans, M. J. M., Bonizzi, P., Karel, J. M. H., Das, M., Kietselaer, B. L. J. H., Jong, M. M. J. D., Prinzen, F. W., Peeters, R. L. M., Westra, R. L., & Volders, P. G. A. (2017). In Vivo Validation of Electrocardiographic Imaging. JACC: Clinical Electrophysiology, 3(3), 232 - 242. https://doi.org/10.1016/j.jacep.2016.11.012More information about this publication
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Cluitmans, M., Brooks, D. H., MacLeod, R., Dossel, O., Guillem, M. S., van Dam, P. M., Svehlikova, J., He, B., Sapp, J., Wang, L., & Bear, L. (2018). Validation and Opportunities of Electrocardiographic Imaging: From Technical Achievements to Clinical Applications. Frontiers in physiology, 9(SEP), Article 1305. https://doi.org/10.3389/fphys.2018.01305More information about this publication
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Nguyen, U. C., Cluitmans, M. J. M., Luermans, J. G. L. M., Strik, M., de Vos, C. B., Kietselaer, B. L. J. H., Wildberger, J. E., Prinzen, F. W., Mihl, C., & Vernooy, K. (2018). Visualisation of coronary venous anatomy by computed tomography angiography prior to cardiac resynchronisation therapy implantation. Netherlands Heart Journal, 26(9), 433-440. https://doi.org/10.1007/s12471-018-1132-2More information about this publication
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Cluitmans, M., Karel, J., Bonizzi, P., Volders, P., Westra, R., & Peeters, R. (2018). Wavelet-promoted sparsity for non-invasive reconstruction of electrical activity of the heart. Medical & Biological Engineering & Computing, 56(11), 2039-2050. https://doi.org/10.1007/s11517-018-1831-2More information about this publication