F. Caiment

Xiftou, K., Jiang, J., Caiment, F., de Kok, T. M., Vinken, M., Sanz-Serrano, J., & Tabernilla, A. (2026). Transcriptomic responses to repeated exposure of human C3A liver spheroids to polystyrene nanoplastics. Archives of Toxicology, 100(10), 4509-4528. https://doi.org/10.1007/s00204-026-04473-1

Lodhi, S., Herwijnen, M. V., Kelly, C., Fowler-Williams, H., Duckworth, C. A., Pritchard, D. M., Caiment, F., de Kok, T. M. C. M., Verheijen, M. C. T., & Jennen, D. G. J. (2026). Colonoid-Based Transcriptomics Reveals Conserved and Model-Specific Mechanisms of Doxorubicin-Induced Intestinal Toxicity. International Journal of Molecular Sciences, 27(16), Article 7072. https://doi.org/10.3390/ijms27167072

Deferme, L., Kocabas, N. A., North, C., van Otterdijk, F., Hinkal, G. W., & Caiment, F. (2026). Polyaromatic hydrocarbon driven developmental toxicity is dependent on the aryl hydrocarbon receptor: A case study with benzo(a)pyrene. Regulatory Toxicology and Pharmacology, 172, Article 106219. Advance online publication. https://doi.org/10.1016/j.yrtph.2026.106219

Guo, K., Verheijen, M., van Herwijnen, M., Caiment, F., & van den Beucken, T. (2026). Reduced NR2F6 expression reshapes the VPA-induced transcriptome in human hepatocytes and increases lipid accumulation. Toxicology, 524, Article 154457. https://doi.org/10.1016/j.tox.2026.154457

Shankar, V., Zahmatkesh, E., Fuentes, L. R., Trujillo, F. M., van de Wetering, W., Lopez-Iglesias, C., Caiment, F., van Blitterswijk, C., Vrij, E., & Giselbrecht, S. (2026). A bioengineering approach to guide non-integrated stem cell-derived embryo model towards yolk sac development and hematopoiesis. Frontiers in Cell and Developmental Biology, 14, Article 1809181. https://doi.org/10.3389/fcell.2026.1809181

Buziau, A. M., Simons, N., Tolan, D. R., Caiment, F., Scheijen, J. L. J. M., van de Waarenburg, M. P., Schalkwijk, C. G., & Brouwers, M. C. G. J. (2026). Endogenous fructose production in patients and mice with aldolase B deficiency. Molecular Genetics and Metabolism, 149(1-2), Article 110219. https://doi.org/10.1016/j.ymgme.2026.110219

Lambrichts, S. M. P., van der Taelen, L., Pastor, I., Leenders, P., Bitsch, N., Majcher, D., Hermes, D., Simmonds, S. J., van Herwijnen, M., Kamps, R., Weltjens, E., Jessen, P. J. J., Steinbusch, H. P., Arentz, F., Wiesmann, M., Kiliaan, A. J., Caiment, F., Kutmon, M., Jones, E. A., ... Foulquier, S. (2026). Downregulation of Trpv4 and Klf2 in brain microvessels is associated with the progression of neurovascular dysfunction and cognitive impairment in a model of heart failure with preserved ejection fraction. Journal of Cerebral Blood Flow and Metabolism. Advance online publication. https://doi.org/10.1177/0271678X261462714

Cramer von Clausbruch, C. A., Verheijen, M., Callegaro, G., Freedman, J. H., Ortega-Vallbona, R., Palomino-Schatzlein, M., Caiment, F., & Weiss, C. (2026). Discrimination of Steatotic and Non-Steatotic Chemicals Through Transcriptome Analysis in Primary Human Hepatocytes. International Journal of Molecular Sciences, 27(9), Article 3825. https://doi.org/10.3390/ijms27093825

Bwanya, B., Verheijen, M. C. T., Hauser, D., de Kok, T. M., Jennen, D. G. J., van den Beucken, T., & Caiment, F. (2026). Single-cell transcriptomics of acetaminophen-induced responses in human 2D and 3D liver microtissues. Archives of Toxicology, 100(4), 1411-1424. https://doi.org/10.1007/s00204-025-04296-6

Davigo, M., Caiment, F., Verheijen, M., van Schooten, F. J., van Herwijnen, M., Mommers, A., Opperhuizen, A., Talhout, R., & Remels, A. H. V. (2025). Alterations in the transcriptome of human primary bronchial epithelial cells exposed to emissions from a heated tobacco product. Biochimica et Biophysica Acta-general Subjects, 1869(12), Article 130869. https://doi.org/10.1016/j.bbagen.2025.130869