PhD conferral Mrs. Rosanne J.H.C.G. Beijers, MSc.
Supervisor: prof.dr. A.M.W.J. Schols
Co-supervisor: dr. H.R. Gosker; dr. B. van den Borst
Keywords: COPD, cardiometabolic risk, normal body weight, low muscle mass, abdominal obesity, nitrate, resveratrol, exercise
"Cardiometabolic risk modulation in normal-weight COPD"
Patients with COPD have an increased risk of developing cardiometabolic diseases such as type 2 diabetes and cardiovascular disease. This dissertation found that the risk not only increases in overweight patients, but also in normal-weight patients with abdominal obesity and low muscle mass. Standard nutrition and exercise interventions in this group of patients focus on improving muscle function and endurance; however, this dissertation found that these interventions did not affect cardiometabolic risk. Instead, lifestyle changes are recommended for this group of patients. We also conducted a controlled experiment to determine whether nitrate has a beneficial effect on cardiometabolic risk, but this was not the case.
UM Bestuursgebouw
Also read
-
13 May13:00
Online PhD Defence Poornima Gopal
"The AGE-RAGE axis and accelerated ageing in COPD"
-
14 May10:00
PhD Defence Evangelia Beslika
"Cardiac Hypertrophy: A translational journey from large animal models to the human disease"
-
14 May16:00
PhD conferral Alessandro Cianfoni
"Stent-screw-Assisted Internal Fixation (SAIF): Minimally-Invasive Vertebral Body Reconstruction in Extensive Neoplastic and Osteoporotic Lesions"