A. Gemmink, Ph.D.

Xia, Y., Caputo, M., Andersson, E., Asiedu, B., Zhang, J., Hou, W., Amrutkar, M., Cansby, E., Gul, N., Gemmink, A., Myers, C., Aghajan, M., Booten, S., Hoy, A. J., Härtlova, A., Lindahl, P., Ståhlberg, A., Schaart, G., Hesselink, M. K. C., ... Mahlapuu, M. (2025). Therapeutic Potential of STE20-Type Kinase STK25 Inhibition for the Prevention and Treatment of Metabolically Induced Hepatocellular Carcinoma. CMGH Cellular and Molecular Gastroenterology and Hepatology, 19(7), Article 101485. https://doi.org/10.1016/j.jcmgh.2025.101485

Sellers, A. J., van Beek, S. M. M., Hashim, D., Baak, R., Pallubinsky, H., Moonen-Kornips, E., Schaart, G., Gemmink, A., Jorgensen, J. A., van de Weijer, T., Kalkhoven, E., Hooiveld, G. J., Kersten, S., Hesselink, M. K. C., Schrauwen, P., Hoeks, J., & Lichtenbelt, W. D. V. M. (2024). Cold acclimation with shivering improves metabolic health in adults with overweight or obesity. Nature Metabolism, 6(12), 2246-2253. Article 1516. https://doi.org/10.1038/s42255-024-01172-y

Chen, S., Wang, Q., Bakker, D., Hu, X., Zhang, L., van der Made, I., Tebbens, A. M., Kovacshazi, C., Giricz, Z., Brenner, G. B., Ferdinandy, P., Schaart, G., Gemmink, A., Hesselink, M. K. C., Rivaud, M. R., Pieper, M. P., Hollmann, M. W., Weber, N. C., Balligand, J.-L., ... Zuurbier, C. J. (2024). Empagliflozin prevents heart failure through inhibition of the NHE1-NO pathway, independent of SGLT2. Basic Research in Cardiology, 119(5), 751-772. https://doi.org/10.1007/s00395-024-01067-9

de Wit-Verheggen, V. H. W., Vanweert, F., Raiko, J., Liénard, V., Schaart, G., Gemmink, A., Nascimento, E. B. M., Hesselink, M. K. C., Wildberger, J. E., Wierts, R., Joris, P. J., Haas, J., Montaigne, D., Staels, B., Phielix, E., Schrauwen, P., Schrauwen-Hinderling, V. B., & van de Weijer, T. (2023). The tissue-specific metabolic effects of the PPARa agonist ciprofibrate in insulin-resistant male individuals: a double-blind, randomized, placebo-controlled crossover study. Obesity, 31(10), 2493-2504. https://doi.org/10.1002/oby.23874

Gemmink, A., Daemen, S., Wefers, J., Hansen, J., van Moorsel, D., Astuti, P., Jorgensen, J. A., Kornips, E., Schaart, G., Hoeks, J., Schrauwen, P., & Hesselink, M. K. C. (2023). Twenty-four hour rhythmicity in mitochondrial network connectivity and mitochondrial respiration; a study in human skeletal muscle biopsies of young lean and older individuals with obesity. Molecular Metabolism, 72(1), Article 101727. https://doi.org/10.1016/j.molmet.2023.101727

de Wit-Verheggen, V. H. W., Schrauwen-Hinderling, V. B., Brouwers, K., Joergensen, J. A., Schaart, G., Gemmink, A., Nascimento, E. B. M., Hesselink, M. K. C., Wildberger, J. E., Segers, P., Montaigne, D., Staels, B., Schrauwen, P., Lindeboom, L., Hoeks, J., & van de Weijer, T. (2023). PCr/ATP ratios and mitochondrial function in the heart. A comparative study in humans. Scientific Reports, 13(1), Article 8346. https://doi.org/10.1038/s41598-023-35041-7

van Beek, S. M. M., Bruls, Y. M. H., Vanweert, F., Fealy, C. E., Connell, N. J., Schaart, G., Moonen-Kornips, E., Jorgensen, J. A., Vaz, F. M., Smeets, E. T. H. C., Joris, P. J., Gemmink, A., Houtkooper, R. H., Hesselink, M. K. C., Bengtsson, T., Havekes, B., Schrauwen, P., & Hoeks, J. (2023). Effect of beta 2-agonist treatment on insulin-stimulated peripheral glucose disposal in healthy men in a randomised placebo-controlled trial. Nature Communications, 14(1), Article 173. https://doi.org/10.1038/s41467-023-35798-5

Op den Kamp, Y. J. M., Gemmink, A., de Ligt, M., Dautzenberg, B., Kornips, E., Jorgensen, J. A., Schaart, G., Esterline, R., Pava, D. A., Hoeks, J., Schrauwen-Hinderling, V. B., Kersten, S., Havekes, B., Koves, T. R., Muoio, D. M., Hesselink, M. K. C., Oscarsson, J., Phielix, E., & Schrauwen, P. (2022). Effects of SGLT2 inhibitor dapagliflozin in patients with type 2 diabetes on skeletal muscle cellular metabolism. Molecular Metabolism, 66, Article 101620. https://doi.org/10.1016/j.molmet.2022.101620

Rodriguez, M. A. D., Deng, L., Gemmink, A., van Weeghel, M., Aoun, M. L., Warnecke, C., Singh, R., Borst, J. W., & Kersten, S. (2021). Hypoxia-inducible lipid droplet-associated induces DGAT1 and promotes lipid storage in hepatocytes. Molecular Metabolism, 47, Article 101168. https://doi.org/10.1016/j.molmet.2021.101168