PhD defence Dina Mirghni Mahjoob

Supervisors: Prof. Dr. Gommert A. van Koeveringe, Prof. Dr. Marco H. Blanker 

Co-supervisors: Dr. Grietje E. Knol-de Vries, Dr. Desiree M.J. Vrijens 

Keywords: Pelvic floor symptoms, Adverse childhood experiences, Depression, Biopsychosocial model

 

"Mind, body, and pelvic floor: Investigating the interplay between Psychosocial health and pelvic floor symptoms"

 

This PhD thesis investigated how pelvic floor symptoms, such as bladder, bowel, sexual problems, and pelvic pain are influenced by psychological and social factors. Pelvic floor symptoms are common, can strongly affect quality of life, and are often difficult to discuss. Traditionally, they are mainly studied from a physical or medical perspective.

Using data from large community-based studies, this thesis examined whether adverse childhood experiences, including emotional, physical, and sexual abuse, as well as neglect, are associated with pelvic floor symptoms in adulthood. In addition, the role of mental health particularly depressive symptoms, was explored. The findings showed that individuals who experienced more adverse events during childhood were more likely to report pelvic floor symptoms later in life. Depressive symptoms partly explained this association.

These results suggest that pelvic floor symptoms are not solely physical conditions, but are shaped by a complex interaction between body, mind, and life experiences. A broader, biopsychosocial approach may improve recognition, communication, and person-centred care.

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