Key words: skull base, chordoma, vestibular schwannoma, proton therapy, Gamma Knife, efficacy and safety, facial nerve imaging

"Radiological and radio-therapeutic nuances in skull base tumors; A focus on efficacy and safety in chordoma and vestibular schwannoma"

This research has dealt with radiological and radio-therapeutic data from two challenging skull base tumours, namely, skull base chordoma and large vestibular schwannoma, aiming to assess the safety and efficacy of the current practices. The focus of this research was on the management of these tumours in combination with the recommended types of radiation therapy, proton therapy, and Gamma Knife radiosurgery. The study also contributed to filling some of the knowledge gaps present in imaging the facial nerve and radiation dose planning, which would have a positive impact on the current practices or provide opportunity for further exploration or improvement of current methods.

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