Dr D.G.J. Jennen
Recent publications
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Li, H.-H., Aubrecht, J., Doktorova, T. Y., Jennen, D., Corton, J. C., Froetschl, R., Mezencev, R., & Yauk, C. L. (2025). Review of Transcriptomic Biomarkers That Predict In Vitro Genotoxicity in Human Cell Lines. Environmental and Molecular Mutagenesis. Advance online publication. https://doi.org/10.1002/em.70004More information about this publication
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Froetschl, R., Corton, J. C., Li, H., Aubrecht, J., Auerbach, S. S., Caiment, F., Doktorova, T. Y., Fujita, Y., Jennen, D., Koyama, N., Meier, M. J., Mezencev, R., Recio, L., Suzuki, T., & Yauk, C. L. (2025). Consensus findings of an International Workshops on Genotoxicity Testing workshop on using transcriptomic biomarkers to predict genotoxicity. Environmental and Molecular Mutagenesis, Article 22645. Advance online publication. https://doi.org/10.1002/em.22645More information about this publication
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Meier, M. J., Caiment, F., Corton, J. C., Froetschl, R., Fujita, Y., Jennen, D., Mezencev, R., & Yauk, C. (2024). Outcome of IWGT workshop on transcriptomic biomarkers for genotoxicity: Key considerations for bioinformatics. Environmental and Molecular Mutagenesis. Advance online publication. https://doi.org/10.1002/em.22644More information about this publication
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Diemar, M. G., Vinken, M., Teunis, M., Krul, C. A. M., Busquet, F., Zajac, J. D., Kandarova, H., Corvi, R., Rossi, M. Z., Kharina, A., Bryndum, L. S., Santillo, M., Bloch, D., Kucheryavenko, O., Panagiotakos, D., Rogiers, V., Beekhuijzen, M., Giusti, A., Najjar, A., ... Roggen, E. L. (2024). Report of the First ONTOX Stakeholder Network Meeting: Digging Under the Surface of ONTOX Together With the Stakeholders. ATLA-Alternatives to laboratory animals, 52(2), 117-131. https://doi.org/10.1177/02611929231225730More information about this publication
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Donovan, S. D. O., Cavill, R., Wimmenauer, F., Lukas, A., Stumm, T., Smirnov, E., Lenz, M., Ertaylan, G., Jennen, D. G. J., van Riel, N. A. W., Driessens, K., Peeters, R. L. M., & de Kok, T. M. C. M. (2023). Application of transfer learning to predict drug-induced human in vivo gene expression changes using rat in vitro and in vivo data. PLOS ONE, 18(11), Article e0292030. https://doi.org/10.1371/journal.pone.0292030More information about this publication
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Jiang, J., van Ertvelde, J., Ertaylan, G., Peeters, R., Jennen, D., de Kok, T. M., & Vinken, M. (2023). Unraveling the mechanisms underlying drug-induced cholestatic liver injury: identifying key genes using machine learning techniques on human in vitro data sets. Archives of Toxicology, 97(11), 2969-2981. https://doi.org/10.1007/s00204-023-03583-4More information about this publication
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Bischoff, N. S., Proquin, H., Jetten, M. J., Schrooders, Y., Jonkhout, M. C. M., Briedé, J. J., van Breda, S. G., Jennen, D. G. J., Medina-Reyes, E. I., Delgado-Buenrostro, N. L., Chirino, Y. I., van Loveren, H., & de Kok, T. M. (2023). Correction: Bischoff et al. The Effects of the Food Additive Titanium Dioxide (E171) on Tumor Formation and Gene Expression in the Colon of a Transgenic Mouse Model for Colorectal Cancer. Nanomaterials 2022, 12, 1256. Nanomaterials, 13(21), Article 2888. https://doi.org/10.3390/nano13212888More information about this publication
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Martens, M., Stierum, R., Schymanski, E. L., Evelo, C. T., Aalizadeh, R., Aladjov, H., Arturi, K., Audouze, K., Babica, P., Berka, K., Bessems, J., Blaha, L., Bolton, E. E., Cases, M., Damalas, D. ., Dave, K., Dilger, M., Exner, T., Geerke, D. P., ... Et al. (2023). ELIXIR and Toxicology: a community in development. F1000Research, 10(1), Article 1129. https://doi.org/10.12688/f1000research.74502.2More information about this publication
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Gall, L., Jardi, F., Lammens, L., Piñero, J., Souza, T. M., Rodrigues, D., Jennen, D. G. J., de Kok, T. M., Coyle, L., Chung, S.-W., Ferreira, S., Jo, H., Beattie, K. A., Kelly, C., Duckworth, C. A., Pritchard, D. M., & Pin, C. (2023). A dynamic model of the intestinal epithelium integrates multiple sources of preclinical data and enables clinical translation of drug-induced toxicity. CPT: Pharmacometrics and Systems Pharmacology, 12(10), 1511-1528. https://doi.org/10.1002/psp4.13029More information about this publication
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Bischoff, N. S., Proquin, H., Jetten, M. J., Schrooders, Y., Jonkhout, M. C. M., Briede, J. J., van Breda, S. G., Jennen, D. G. J., Medina-Reyes, E. I., Delgado-Buenrostro, N. L., Chirino, Y. I., van Loveren, H., & de Kok, T. M. (2023). Reply to Kaminski, NE; Cohen, SM Comment on "Bischoff et al. The Effects of the Food Additive Titanium Dioxide (E171) on Tumor Formation and Gene Expression in the Colon of a Transgenic Mouse Model for Colorectal Cancer. Nanomaterials 2022, 12, 1256". Nanomaterials, 13(9), Article 1552. https://doi.org/10.3390/nano13091552More information about this publication