PhD defence Navya Premaraj

Supervisor: Prof. Dr. Ron M. A. Heeren

Co-supervisors: Dr. Kèvin Knoops, Dr. C. López-Iglesias

Keywords: Jet vitrification, Cryo EM, Cooling rate, Synchronization

 

"Frozen in Time: Visualizing the Glassy State of Life Cryo-EM sample preparation by jet vitrification"

 

This thesis explores advancements in cryo-electron tomography (cryo-ET) sample preparation methods to enhance the study of cellular structures and processes in their native environments. The research focuses on innovations in vitrification techniques, sample quality, and workflow improvements, with a particular emphasis on the potential of jet vitrification as a more efficient alternative to conventional methods.

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