G.G.H. van den Akker

Gosselink, I. F., Leonhardt, P., Höppener, E. M., Smelt, R., Drittij, M. J., Davigo, M., van den Akker, G. G. H., Kooter, I. M., Welting, T. J. M., van Schooten, F. J., & Remels, A. H. V. (2025). Size- and polymer-dependent toxicity of amorphous environmentally relevant micro- and nanoplastics in human bronchial epithelial cells. Microplastics and Nanoplastics, 5(1), Article 19. https://doi.org/10.1186/s43591-025-00126-9

Neefjes, M., Housmans, B. A. C., Kaffa, C., Thielen, N. G. M., Joosten, L. A. B., van den Ende, C. H. M., Vitters, E. L., van den Akker, G. G. H., Welting, T. J. M., van Caam, A. P. M., & van der Kraan, P. M. (2025). Cell-integrated serum-induced signalling patterns can differentiate between hand and knee osteoarthritis patients. Rheumatology, 64(6), 3929-3937. https://doi.org/10.1093/rheumatology/keae555

Kibble, M. J., Ferreira, M. J. S., Usta, Y. H., van den Akker, G. G. H., Moxon, S. R., Baird, P., Hoyland, J. A., Domingos, M. A. N., & Richardson, S. M. (2025). Suspension bioprinted whole intervertebral disc analogues enable regional stiffness- and hypoxia-regulated matrix secretion by primary human nucleus pulposus and annulus fibrosus cells. Acta Biomaterialia. Advance online publication. https://doi.org/10.1016/j.actbio.2025.05.015

Stassen, R. H. M. J., van den Akker, G. G. H., Caron, M. M. J., Surtel, D. A. M., Cremers, A., van Rhijn, L. W., & Welting, T. J. M. (2025). TGF-ß Enhances Phosphate-Driven Calcification of Human OA Articular Chondrocytes. Calcified Tissue International, 116(1), Article 57. https://doi.org/10.1007/s00223-025-01365-x

Niessink, T., Stassen, R. H. M. J., Kischkel, B., Vuscan, P., Emans, P. J., van den Akker, G. G. H., Janssen, M., Joosten, L. A. B., Otto, C., Welting, T. J. M., & Jansen, T. L. (2024). Discovery of calcite as a new pro-inflammatory calcium-containing crystal in human osteoarthritic synovial fluid. Osteoarthritis and Cartilage, 32(10), 1261-1272. https://doi.org/10.1016/j.joca.2024.05.004

van den Akker, G. G. H., Chabronova, A., Housmans, B. A. C., van der Vloet, L., Surtel, D. A. M., Cremers, A., Marchand, V., Motorin, Y., Caron, M. M. J., Peffers, M. J., & Welting, T. J. M. (2024). TGF-β2 Induces Ribosome Activity, Alters Ribosome Composition and Inhibits IRES-Mediated Translation in Chondrocytes. International Journal of Molecular Sciences, 25(9), Article 5031. https://doi.org/10.3390/ijms25095031

Ripmeester, E. G. J., Steijns, J. S. J. J., Wijnands, K. A. P., Stassen, R. H. M. J., Pitelka, V., Peeters, L. C. W., Cremers, A., Astryde, N. M. S. A., Chabronova, A., Surtel, D. A. M., Emans, P. J., van den Akker, G. G. H., van Rietbergen, B., van Rhijn, L. W., Caron, M. M. J., & Welting, T. J. M. (2024). The BMP7-Derived Peptide p[63-82] Reduces Cartilage Degeneration in the Rat ACLT-pMMx Model for Posttraumatic Osteoarthritis. Cartilage. Advance online publication. https://doi.org/10.1177/19476035241233659

Steijns, J. S. J. J., Green, D., Peeters, L. C. W., Emans, P. J., Boymans, T. A., Stassen, R. H., van den Akker, G. G. H., Cremers, A., Jutten, L. M. C., Anderson, J. R., Peffers, M. J., Caron, M. M. J., & Welting, T. J. M. (2024). Proteomic characterization of regenerated cartilage following knee joint distraction; a human case-study. Connective Tissue Research, 65(6), 486-496. https://doi.org/10.1080/03008207.2024.2440716

Laagland, L. T., Bach, F. C., Riemers, F. M., Erdmann, G., Braun, T. S., van den Akker, G. G. H., Schmitz, T. C., Creemers, L. B., Sachse, C., Maitre, C. L. L., Welting, T. J. M., Ito, K., Templin, M. F., & Tryfonidou, M. A. (2023). Notochordal Cell-Derived Matrix Inhibits Mapk Signaling In The Degenerative Disc Environment. European Cells & Materials, 46(1), 57-90. https://doi.org/10.22203/eCM.v046a04

Anderson, J. R., Johnson, E., Jenkins, R., Jacobsen, S., Green, D., Walters, M., Bundgaard, L., Hausmans, B. A. C., van den Akker, G., Welting, T. J. M., Chabronova, A., Kharaz, Y. A., Clarke, E. J., James, V., & Peffers, M. J. (2023). Multi-Omic Temporal Landscape of Plasma and Synovial Fluid-Derived Extracellular Vesicles Using an Experimental Model of Equine Osteoarthritis. International Journal of Molecular Sciences, 24(19), Article 14888. https://doi.org/10.3390/ijms241914888