Dr E.J.M. Speel

Trandafir, T. E., Heijboer, F. W. J., Akram, F., Derks, J. L., Li, Y., Hillen, L. M., Speel, E.-J. M., Megyesfalvi, Z., Dome, B., Stubbs, A. P., Dingemans, A.-M. C., & von der Thüsen, J. H. (2025). Deep Learning–Based Retinoblastoma Protein Subtyping of Pulmonary Large-Cell Neuroendocrine Carcinoma on Small Hematoxylin and Eosin–Stained Specimens. Laboratory Investigation, 105(9), Article 104192. https://doi.org/10.1016/j.labinv.2025.104192

Mulder, F. J., de Ruiter, E. J., Gielgens, T. F. B., Farshadpour, F., de Bree, R., van den Hout, M. F. C. M., Kremer, B., Willems, S. M., & Speel, E. J. M. (2025). Frequent PD-L1 expression in oral squamous cell carcinoma of non-smokers and non-drinkers, and association of tumor infiltrating lymphocytes with favorable prognosis. Translational Oncology, 55, Article 102357. https://doi.org/10.1016/j.tranon.2025.102357

Chteinberg, E., Kolarova, J., Vogt, J., Macamo, A., Bormann, F., Kretzmer, H., Speel, E. J., van den Oord, J., Schneider, C., Stilgenbauer, S., Becker, J. C., Winnepenninckx, V., Biessen, E., Zenke, M., Kurz, A. K., Siebert, R., & zur Hausen, A. (2025). The significance of PAX5 in Merkel cell carcinoma. Journal of Pathology, 266(1), 81-94. https://doi.org/10.1002/path.6410

Leunissen, D. J. G., Moonen, L., Alcala, N., Speel, E. J. M., & Derks, J. L. (2025). A Response to the Letter to the Editor: “Linear Versus Non-Linear: Debunking Critiques on PCA Use in Molecular Subgrouping of Pulmonary Carcinoids". Journal of Thoracic Oncology, 20(4), e55-e56. https://doi.org/10.1016/j.jtho.2025.01.012

Leunissen, D. J. G., Moonen, L., Thüsen, J. H. V. D., den Bakker, M. A., Hillen, L. M., van Weert, T. J. J., Hausen, A. Z., van den Bosch, T. P. P., Lap, L. M. V., Damhuis, R. A., Reynaert, N. L., van den Broek, E. C., Fernandez-Cuesta, L., Foll, M., Alcala, N., Oates, A. S., Dingemans, A.-M. C., Speel, E. J. M., Derks, J. L., & PALGA Group (2025). Identification of Defined Molecular Subgroups on the Basis of Immunohistochemical Analyses and Potential Therapeutic Vulnerabilities of Pulmonary Carcinoids. Journal of Thoracic Oncology, 20(4), 451-464. https://doi.org/10.1016/j.jtho.2024.11.018

Moonen, L., Derks, J. L., den Bakker, M. A., Hillen, L. M., Jan van Suylen, R., von der Thüsen, J. H., Lap, L. M. V., Marijnissen, B. J. C. A., Damhuis, R. A., Smits, K. M., van den Broek, E. C., Buikhuisen, W. A., Dingemans, A.-M. C., Speel, E. J. M., & PALGA Group (2025). OTP, CD44, and Ki-67: A prognostic marker panel for relapse free survival in patients with surgically resected pulmonary carcinoid. Modern Pathology, 38(3), Article 100677. https://doi.org/10.1016/j.modpat.2024.100677

Verhees, F., Demers, I., Legemaate, D., Jacobs, R., Hoeben, A., Kremer, B., & Speel, E.-J. (2025). Exploring the antiproliferative effect of PI3K/Akt/mTOR pathway and CDK4/6 inhibitors in human papillomavirus-positive and -negative head and neck squamous cell carcinoma cell lines. International Journal of Oncology, 66(2), Article 13. https://doi.org/10.3892/ijo.2025.5719

Froyen, G., Volders, P.-J., Geerdens, E., Berden, S., van der Meulen, J., De Cock, A., Vermeire, S., Van Huysse, J., de Barsy, M., Beniuga, G., de Leng, W. W. J., Jansen, A. M. L., Demers, I., Ozgur, Z., Dubbink, H. J., Speel, E.-J. M., van IJcken, W. F. J., & Maes, B. (2025). Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics. Molecular oncology. Advance online publication. https://doi.org/10.1002/1878-0261.13812

Heijboer, F. W. J., Mulders, T. A., van Straten, M., Moonen, L., Speel, E. M., von der Thusen, J. H., Derks, J. L., & Dingemans, A. C. (2024). Radiological follow-up in patients with resected pulmonary carcinoids: Should we reduce radiation exposure? Lung Cancer, 198, Article 108030. https://doi.org/10.1016/j.lungcan.2024.108030

Moonen, L., Derks, J., Hillen, L. M., van Suylen, R. J., den Bakker, M., Thusen, J. V. D., Damhuis, R., Buikhuisen, W., van den Broek, E. C., Maessen, J., Maat, A., van Schil, P., Speel, E.-J. M., & Dingemans, A.-M. C. (2024). Disease relapse in relation to lymph node sampling in lung carcinoid patients. Endocrine-Related Cancer, 31(9), Article e230202. https://doi.org/10.1530/ERC-23-0202