proefschrift_def._r_van_de_goor.pdf
(4.27 MB, PDF)
… without the prior written permission of the author or the publisher. Cover design/layout: Publiss | www.publiss.nl Print: Ridderprint.nl | www.ridderprint.nl ISBN: 978-94-6458-918-4 Printing of this thesis was financially supported by: The eNose Company, Noviotissue B.V., ALK, Allergy therapeutics, DOS Medical. Non-invasive diagnostic of head and neck cancer: feasibility of a portable electronic nose PROEFSCHRIFT ter verkrijging van de graad van doctor aan de Universiteit Maastricht, op gezag … There are differences in tumor microenvironment and biology between the subsites of HNSCC, but there are also similarities between these squamous cell carcinomas. They all arise from the squamous epithelia of the head and neck region and are in direct contact with the airways. One can find circulating tumor cells at distant places in the body.53 In a previous study with Tedlar bags and a laboratory e-nose, we were able to discriminate 26 healthy controls from 36 patients diagnosed with HNSCC with a … by an experienced head and neck tumor board using the American Joint Committee on Cancer Staging Manual (7th edition). Patients’ smoking habits were documented. Their smoking history was reported in pack years, which were calculated using an online pack year calculator.24 Smoking cessation was defined as no smoking for at least 1 month. Side effects or adverse effects during or shortly after measurement were documented. Oral informed consent was obtained from all patients. The study …