Zoekresultaten

… short-term firm benefits of shareholders rather than on long-term sustainable value creation for diverse stakeholders. Corporate governance for sustainable and competitive companies has therefore become a strategic issue for the European Commission. This includes better risk management and the provision of reliable corporate information that facilitates decision-making and influences firm behaviour. This requires responsible accounting and governance, and ultimately responsible finance as a catalyst for responsible business. We are just beginning to understand how these necessary transformations affect firm performance, organizational design, organizational culture, and corporate leadership and a range of questions remains for us to further explore. For instance, how can we train and prepare leaders and employees for situations and problems which by its very nature are ill-defined, dynamic, and complex or present wicked ethical dilemmas? Further questions are related to defining what are norms and values that …

… of Public Policy and Management (SPPM) Co-investigators  Lili WANG, Senior researcher, UNU-MERIT, School of Business and Economics (SBE), Maastricht University  Bartel van der WALLE, School of Business and Economics (SBE) The research proposal This project seeks to examine the synergies between digital and green transformations in China. On the one hand, the high-profile strategy of the ‘ecological civilization’ is a major driver of green transformation in areas of green consumption, low … extent, how and in which areas is the adoption of digital technologies speeding up or changing the direction of the pathway towards ecological civilization? These are the high-level questions the project seeks to investigate. Techniques to be used This project will not only examine new and emerging digital technologies but will also apply computational social science methods in examining the links between green transformation. Examples of methods that can be used are: (a) big-data analytics to examine difference between digital technology adopters and non-adopters in the green economy, (b) agent-based modelling to model of green transformation processes with different degrees and types of digital …

… Drug to Market Discovery Research – preclinical, in test tubes then animals Brain Target Clinical Research & Development In humans; healthy volunteers then patients Courses aligned to drug research & development pipeline Core Courses Practicals Workshops Parallel Courses This is about finding new medicinal drugs and making them work for dementia, depression, schizophrenia, autism, ADHD, . . . . . . ., basically all neuropsychiatric diseases that can be targeted biologically Discovery ~7yrs Development ~8yrs Registration Drug to Market Discovery Research – preclinical, in test tubes then animals Brain Target Clinical Research & Development In humans; healthy volunteers then patients Courses …

… Faculty of Humanities and Sciences Project title: Thermal immunosensors for early stage cancer diagnosis Project leader: Professor Thomas Cleij Function: Group Leader Smart Devices Research Group and Dean Sciences Maastricht University Collaborators: Dr. Bart van Grinsven (UM), Dr. Erik Steen Redeker (UM), Dr. Hanne Diliën (UM), Dr. … Immunosensors exploit the remarkable affinity an antibody has for its antigen. However, antibodies are fragile and difficult to incorporate into sensor modules and immunosensors are typically coupled to readout methods that require post-data analysis. This limits their use in high throughput cancer screening. Single-domain antibodies, or nanobodies, may well alleviate the drawbacks associated with traditional antibodies due to their superior chemical and thermal stability. Additionally, the smart devices research group of Maastricht …

… heart for over 100 years. It uses 12 electrodes to record and display 1D electrical signals, measured on the patient’s body, reflecting what happens on the heart. A new technique, developed in the last 25 years, is electrocardiographic imaging (ECGI). This technique uses a vest with about 200 electrodes and is now slowly finding its way into clinical practice. By solving the “inverse problem of electrocardiography”, the 200 recorded signals are used to compute a 3D visualization of electrical activity on the heart, and to create movies of electrical propagation. This allows for more advanced diagnosis and better mechanistic understanding. Currently, this technique is expensive and requires CT or MRI-scans to build a sufficiently accurate patient-specific model. Hypothesis and Objectives: The goal of this project is to develop a combination of mathematical and machine learning techniques (“smart mathematics”!), which makes ECGI work without scans …

… and life on the other. While closing plastic carbon cycles timely relies on selection of biobased building blocks, plastic pollution jeopardizes the closure of cycles and moreover life. Biodegradable polymers exist, typically polyesters that can be derived from natural and fossil resources. However, these polymers either (i) need human intervention by raising temperature above the glass transition temperature (Tg) (e.g. polylactides) in industrial composting, or (ii) are uncontrolled … Molecular mobility in the non-crystalline domains above Tg is trivial for the polymer chain to adapt molecular conformation and configure to the active site of enzymes. Inspired by silk, we propose polyamides where a water dependence of Tg, can (i) be tuned via polyamide polarity and (ii) used as actuator of biological degradation in nature. The role of crystal surface chain topology on operating modes of enzymes and consequent degradation rates were reported for polyhydroxyalkanoates … our recent lab work, based on defined crystal dimensions and surface chain topology in silk fibres, polyglycine crystals (a model for silk crystals), polyamide 6 crystals and fibres, hint to enthalpy in combination with crystal dimensions. Following this approach we wish to understand the cause for biodegradability of polymer crystals and how to design processing conditions to realize these biodegradable polyamide crystals without sacrificing performance. Setting and Methods: Work will be …

… Faculty of Health, Medicine and Life Sciences Institute for Education Education Office APPLICATION FORM FOR NON-DEGREE SEEKING STUDENT - BACHELOR ACADEMIC YEAR 2022-2023 (Submit this form no later than eight weeks before the start of the course period concerned). Please type the required information. Name and Initials Date and Place of Birth Address Postcode and Town/City Telephone number Email address Prior Education and Institute For a description of the courses, their module codes and the periods in which the courses are offered, you can visit our website: https://www.maastrichtuniversity.nl/education/bachelor/organisation/4138 I wish to participate in the following courses: Study programme* Period Module code** Course title * Bachelor Biomedical Sciences (BMS) / European Public … transcript of records and permission from your own Board of Examiners · If you are not currently enrolled at a different university (not a university of applied sciences) in the Netherlands: a certified copy of your pre-university diploma Please send this application form and the documents to the following email address no later than eight weeks before the start of the course: examensfhml@maastrichtuniversity.nl Please note: · Your application will not be legally valid until the FHML has officially …

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… short-term firm benefits of shareholders rather than on long-term sustainable value creation for diverse stakeholders. Corporate governance for sustainable and competitive companies has therefore become a strategic issue for the European Commission. This includes better risk management and the provision of reliable corporate information that facilitates decision-making and influences firm behaviour. This requires responsible accounting and governance, and ultimately responsible finance as a catalyst for responsible business. We are just beginning to understand how these necessary transformations affect firm performance, organizational design, organizational culture, and corporate leadership and a range of questions remains for us to further explore. For instance, how can we train and prepare leaders and employees for situations and problems which by its very nature are ill-defined, dynamic, and complex or present wicked ethical dilemmas? Further questions are related to defining what are norms and values that …

… been laid in over some 100 Dutch towns and villages, predominantly for Jews. The laying of stumbling stones has turned these towns into memoryscapes, in which the unsuspecting passer-by will stumble over reminders of a traumatic past. The creation of this dispersed monument has transformed the commemoration of the Holocaust in the Netherlands: as stumbling stones focus on every victim individually, this creates a much more personalized and unmediated way of commemorating. This enables post-war generations to empathize with this person and his of her life story and thus to turn abstract numbers into a face and a story present-day people can connect to. Of the Dutch Jews, 102,000 were killed, making the Netherlands the country in Western Europe with the highest percentage Jews having been murdered. In my contribution, I will assess some important issues related to this project and its …