M.K.C. Hesselink

op den Kamp-bruls, Y. M. H., op den Kamp, Y. J. M., Veeraiah, P., Perez, R. Z., Phielix, E., Havekes, B., Schaart, G., Kornips, E., Berendsen, B. R. B., Virmani, A., Wildberger, J. E., Houtkooper, R. H., Hesselink, M. K. C., Schrauwen, P., & Schrauwen-Hinderling, V. B. (2025). Carnitine supplementation improves insulin sensitivity and skeletal muscle acetylcarnitine formation in patients with type 2 diabetes. Diabetes Obesity & Metabolism, 27(5), 2864-2877. https://doi.org/10.1111/dom.16298

Xia, Y., Caputo, M., Andersson, E., Asiedu, B., Zhang, J., Hou, W., Amrutkar, M., Cansby, E., Gul, N., Gemmink, A., Myers, C., Aghajan, M., Booten, S., Hoy, A. J., Härtlova, A., Lindahl, P., Ståhlberg, A., Schaart, G., Hesselink, M. K. C., ... Mahlapuu, M. (2025). Therapeutic Potential of STE20-Type Kinase STK25 Inhibition for the Prevention and Treatment of Metabolically Induced Hepatocellular Carcinoma. CMGH Cellular and Molecular Gastroenterology and Hepatology, 19(7), Article 101485. https://doi.org/10.1016/j.jcmgh.2025.101485

Sellers, A. J., van Beek, S. M. M., Hashim, D., Baak, R., Pallubinsky, H., Moonen-Kornips, E., Schaart, G., Gemmink, A., Jorgensen, J. A., van de Weijer, T., Kalkhoven, E., Hooiveld, G. J., Kersten, S., Hesselink, M. K. C., Schrauwen, P., Hoeks, J., & Lichtenbelt, W. D. V. M. (2024). Cold acclimation with shivering improves metabolic health in adults with overweight or obesity. Nature Metabolism, 6(12), 2246-2253. Article 1516. https://doi.org/10.1038/s42255-024-01172-y

Mevenkamp, J., Bruls, Y. M. H., Mancilla, R., Grevendonk, L., Wildberger, J. E., Brouwers, K., Hesselink, M. K. C., Schrauwen, P., Hoeks, J., Houtkooper, R. H., Buitinga, M., de Graaf, R. A., Lindeboom, L., & Schrauwen-Hinderling, V. B. (2024). Development of a 31P magnetic resonance spectroscopy technique to quantify NADH and NAD+ at 3 T. Nature Communications, 15(1), Article 9159. https://doi.org/10.1038/s41467-024-53292-4

Chen, S., Wang, Q., Bakker, D., Hu, X., Zhang, L., van der Made, I., Tebbens, A. M., Kovacshazi, C., Giricz, Z., Brenner, G. B., Ferdinandy, P., Schaart, G., Gemmink, A., Hesselink, M. K. C., Rivaud, M. R., Pieper, M. P., Hollmann, M. W., Weber, N. C., Balligand, J.-L., ... Zuurbier, C. J. (2024). Empagliflozin prevents heart failure through inhibition of the NHE1-NO pathway, independent of SGLT2. Basic Research in Cardiology, 119(5), 751-772. https://doi.org/10.1007/s00395-024-01067-9

Andriessen, C., Doligkeit, D., Moonen-Kornips, E., Mensink, M., Hesselink, M. K. C., Hoeks, J., & Schrauwen, P. (2023). The impact of prolonged fasting on 24h energy metabolism and its 24h rhythmicity in healthy, lean males: A randomized cross-over trial. Clinical Nutrition, 42(12), 2353-2362. https://doi.org/10.1016/j.clnu.2023.10.010

de Wit-Verheggen, V. H. W., Vanweert, F., Raiko, J., Liénard, V., Schaart, G., Gemmink, A., Nascimento, E. B. M., Hesselink, M. K. C., Wildberger, J. E., Wierts, R., Joris, P. J., Haas, J., Montaigne, D., Staels, B., Phielix, E., Schrauwen, P., Schrauwen-Hinderling, V. B., & van de Weijer, T. (2023). The tissue-specific metabolic effects of the PPARa agonist ciprofibrate in insulin-resistant male individuals: a double-blind, randomized, placebo-controlled crossover study. Obesity, 31(10), 2493-2504. https://doi.org/10.1002/oby.23874

Mancilla, R., Pava-Mejia, D., van Polanen, N., de Wit, V., Bergman, M., Grevendonk, L., Jorgensen, J., Kornips, E., Hoeks, J., Hesselink, M. K. C., & Schrauwen-Hinderling, V. B. B. (2023). Invasive and noninvasive markers of human skeletal muscle mitochondrial function. Physiological Reports, 11(12), Article e15734. https://doi.org/10.14814/phy2.15734

Gemmink, A., Daemen, S., Wefers, J., Hansen, J., van Moorsel, D., Astuti, P., Jorgensen, J. A., Kornips, E., Schaart, G., Hoeks, J., Schrauwen, P., & Hesselink, M. K. C. (2023). Twenty-four hour rhythmicity in mitochondrial network connectivity and mitochondrial respiration; a study in human skeletal muscle biopsies of young lean and older individuals with obesity. Molecular Metabolism, 72(1), Article 101727. https://doi.org/10.1016/j.molmet.2023.101727

de Wit-Verheggen, V. H. W., Schrauwen-Hinderling, V. B., Brouwers, K., Joergensen, J. A., Schaart, G., Gemmink, A., Nascimento, E. B. M., Hesselink, M. K. C., Wildberger, J. E., Segers, P., Montaigne, D., Staels, B., Schrauwen, P., Lindeboom, L., Hoeks, J., & van de Weijer, T. (2023). PCr/ATP ratios and mitochondrial function in the heart. A comparative study in humans. Scientific Reports, 13(1), Article 8346. https://doi.org/10.1038/s41598-023-35041-7