Tom Houben, Ph.D. (T.)

Westheim, A. J. F., Dubois, L. J., Prades-Sagarra, E., Chan, J., van der Wiel, A. M. A., Lieuwes, N. G., Biemans, R., Cong, Y., Houben, T., Meesters, D. M., Yaromina, A., van Dijk, M., van Bergenhenegouwen, J., van Helvoort, A., Langen, R. C. J., Penders, J., Shiri-sverdlov, R., & Theys, J. (2026). The Effect of Dietary Fiber Compositions on the Therapeutic Outcome of Combined Radio- and Immunotherapy in a Preclinical Cancer Model. Molecular Nutrition & Food Research, 70(2), Article e70370. https://doi.org/10.1002/mnfr.70370

Peters, L., Rakateli, L., Huchzermeier, R., Bonnin-Marquez, A., Maas, S. L., Lin, C., Jans, A., Geng, Y., Gorter, A., Gijbels, M., Rensen, S., Olinga, P., Hendrikx, T., Krawczyk, M., Brisbois, M., Jankowski, J., Bidzhekov, K., Weber, C., Biessen, E. A. L., ... van der Vorst, E. (2025). MicroRNA-26b protects against MASH development in mice and can be efficiently targeted with lipid nanoparticles. Elife, 13. https://doi.org/10.7554/eLife.97165

Vermeulen, I., Li, M., van Mourik, H., Yadati, T., Eijkel, G., Balluff, B., Godschalk, R., Temmerman, L., Biessen, E. A. L., Kulkarni, A., Theys, J., Houben, T., Cillero-Pastor, B., & Shiri-Sverdlov, R. (2025). Inhibition of intracellular versus extracellular cathepsin D differentially alters the liver lipidome of mice with metabolic dysfunction-associated steatohepatitis. FEBS Journal, 292(7), 1781-1797. https://doi.org/10.1111/febs.17358

Li, M., Houben, T., Bitorina, A. V., Meesters, D. M., Israelsen, M., Kjærgaard, M., Koek, G. H., Hendrikx, T., Verbeek, J., Krag, A., Thiele, M., & Shiri-Sverdlov, R. (2024). Plasma cathepsin D as an early indicator of alcohol-related liver disease. JHEP Reports, 6(9), Article 101117. https://doi.org/10.1016/j.jhepr.2024.101117

van der Heijden, A. R., & Houben, T. (2023). Lipids in major depressive disorder: new kids on the block or old friends revisited? Frontiers in Psychiatry, 14(1), Article 1213011. https://doi.org/10.3389/fpsyt.2023.1213011

Groenen, A. G., La Rose, A. M., Li, M., Bazioti, V., Svendsen, A. F., Kloosterhuis, N. J., Ausema, A., Pranger, A., Heiner-Fokkema, M. R., Niezen-Koning, K. E., Houben, T., Shiri-Sverdlov, R., & Westerterp, M. (2022). Elevated granulocyte-colony stimulating factor and hematopoietic stem cell mobilization in Niemann-Pick type C1 disease. Journal of Lipid Research, 63(2), Article 100167. https://doi.org/10.1016/j.jlr.2021.100167

Barthelemy, A., Demais, V., Stancu, I. C., Vasile, E., Houben, T., Reber, M., Pallottini, V., Perraut, M., Reibel, S., & Pfrieger, F. W. (2021). Glial contribution to cyclodextrin-mediated reversal of cholesterol accumulation in murine NPC1-deficient neurons in vivo. Neurobiology of Disease, 158, Article 105469. https://doi.org/10.1016/j.nbd.2021.105469

Ahmad, F., Mitchell, R. D., Houben, T., Palo, A., Yadati, T., Parnell, A. J., Patel, K., Shiri-Sverdlov, R., & Leake, D. S. (2021). Cysteamine Decreases Low-Density Lipoprotein Oxidation, Causes Regression of Atherosclerosis, and Improves Liver and Muscle Function in Low-Density Lipoprotein Receptor-Deficient Mice. Journal of the American Heart Association, 10(18), Article e017524. https://doi.org/10.1161/JAHA.120.017524

Houben, T., Yadati, T., De Kruijf, R., Gijbels, M. J. J., Luiken, J. J. F. P., Van Zandvoort, M., Kapsokalyvas, D., Lutjohann, D., Westerterp, M., Plat, J., Leake, D., & Shiri-Sverdlov, R. (2021). Pro-Inflammatory Implications of 2-Hydroxypropyl-β-cyclodextrin Treatment. Frontiers in Immunology, 12, Article 716357. https://doi.org/10.3389/fimmu.2021.716357