proefschrift-rianne-willemsen_com_kleiner_formaat.pdf
(13.75 MB, PDF)
… advanced squamous cell carcinoma of the lung, but not in locally advanced squamous cell carcinoma of the head and neck 69 Chapter 5 The predictive and prognostic value of weight loss and body composition prior to and during treatment with immune checkpoint inhibitors in patients with recurrent or metastatic head and neck cancer 93 DETERMINANTS AND TREATMENT OF IMPAIRED NUTRITIONAL INTAKE IN HEAD AND NECK CANCER PATIENTS Chapter 6 Tooth extractions prior to chemoradiotherapy or bioradiotherapy … disruption of these systems may lead to muscle atrophy and decreased muscle function. [66] Furthermore, pro-inflammatory cytokines (i.e., IL-6 and TNF-α) have a marked effect on the lipid metabolism through the induction of lipolysis and glucose homeostasis. General introduction 17 1 [67] Lipolysis may fuel tumor growth and alterations in lipid-metabolic pathways have been associated with disease progression and metastasis in other cancers. [68] The mechanisms through which cytokines affect … Yen, C.Y. Lin, K.P. Chang, and K.F. Lei, Pretreatment subcutaneous adipose tissue predicts the outcomes of patients with head and neck cancer receiving definitive radiation and chemoradiation in Taiwan. Cancer Med, 2018 DOI: 10.1002/cam4.1365. 11. Bishop, S. and W.M. Reed, The provision of enteral nutritional support during definitive chemoradiotherapy in head and neck cancer patients. J Med Radiat Sci, 2015. 62(4): p. 267-76 DOI: 10.1002/jmrs.132. 12. Wang, C., J.M. Vainshtein, M. Veksler, P.E. …