Aaron Isaacs (A.J.)

Habibi, Z., Verhaert, D. V. M., Ozgul, O. F., Betz, K., Hermans, B. J. M., Philippens, S. A. M., Chaldoupi, S.-M., Maesen, B., Sandgren, E., Maessen, J. G., Isaacs, A. J., Westra, S. W., Nijveldt, R., Zeemering, S., Vernooy, K., Linz, D., & Schotten, U. (2026). Pre-procedural time spent in atrial fibrillation using intermittent ECG monitoring is associated with arrhythmia recurrence after ablation: the ISOLATION cohort study. EP Europace, 28(3), Article euag044. https://doi.org/10.1093/europace/euag044

D'alessandro, E., Scaf, B., Opacic, D., van Hunnik, A., Sobota, V., Kuiper, M., Viola, M., Hutschalik, T., Langione, M., Pioner, J. M., Munts, C., Simons, J., Winters, J., Isaacs, A., Heitmeier, S., Stoll, M., van Oerle, R., Ten Cate, H., Spronk, H. M. H., ... Schotten, U. (2026). Rivaroxaban Treatment Prevents Atrial Myocyte Hypertrophy in Goats with Persistent Atrial Fibrillation by Inhibition of Protease-Activated Receptor-1. Thrombosis and Haemostasis. Advance online publication. https://doi.org/10.1055/a-2761-6106

Kawczynski, M. J., Gilbers, M. D., Winters, J., Maesen, B., Isaacs, A., Linz, D., Rienstra, M., van Gelder, I., Maessen, J. G., Bidar, E., & Schotten, U. (2025). Right atrial endomysial fibrosis is associated with increased postoperative atrial fibrillation burden during 2.5 years of continuous rhythm monitoring after cardiac surgery including atrial arrhythmia surgery: RACE V Tissue Bank Study. EP Europace, 27(9), Article euaf207. https://doi.org/10.1093/europace/euaf207

Habibi, Z., Verhaert, D. V. M., Betz, K., Hermans, B. J. M., Winters, J., Philippens, S. A. M., Chaldoupi, S. M., Maesen, B., Maessen, J. G., Isaacs, A., Westra, S. W., Nijveldt, R., Gillet, L., Wienhues-Thelen, U. H., Koehler, M., Zeemering, S., Vernooy, K., Linz, D., & Schotten, U. (2025). Association of atrial fibrillation burden and clinical profile with blood biomarkers: Results from the ISOLATION Ablation Cohort. Heart Rhythm O2, 6(5), 661-670. https://doi.org/10.1016/j.hroo.2025.02.017

Smits, K. C., Bressi, E., Rademakers, L. M., Rijks, J. H. J., van Stipdonk, A. M. W., Engels, E. B., Isaacs, A., Hermans, B. J. M., Grieco, D., Luermans, J. G. L. M., Vernooy, K., Prinzen, F. W., & Nguyen, U. C. (2025). Time-dependent repolarization changes following left bundle branch area pacing vs. conventional biventricular pacing in patients with dyssynchronous heart failure. EP Europace, 27(3), Article euaf034. https://doi.org/10.1093/europace/euaf034

Gilbers, M. D., Kawczynski, M. J., Bidar, E., Maesen, B., Isaacs, A., Winters, J., Linz, D., Rienstra, M., van Gelder, I., Maessen, J. G., & Schotten, U. (2025). Determinants and impact of postoperative atrial fibrillation burden during 2.5 years of continuous rhythm monitoring after cardiac surgery: Results from the RACE V prospective cohort study. Heart Rhythm, 22(3), 647-660. https://doi.org/10.1016/j.hrthm.2024.08.014

Isaacs, A., Zeemering, S., Winters, J., Batlle, M., Bidar, E., Boukens, B., Casadei, B., Chua, W., Crijns, H. J. G. M., Fabritz, L., Guasch, E., Hatem, S. N., Hermans, B., Kääb, S., Kawczynski, M., Maesen, B., Maessen, J., Mont, L., Sinner, M. F., ... Stoll, M. (2025). Lateral Atrial Expression Patterns Provide Insights into Local Transcription Disequilibrium Contributing to Disease Susceptibility. Circulation: Genomic and Precision Medicine, 18(1), Article e004594. https://doi.org/10.1161/CIRCGEN.124.004594

Winters, J., Kawczynski, M. J., Gilbers, M. D., Isaacs, A., Zeemering, S., Bidar, E., Maesen, B., Rienstra, M., van Gelder, I., Verheule, S., Maessen, J. G., & Schotten, U. (2024). Circulating BMP10 Levels Associate With Late Postoperative Atrial Fibrillation and Left Atrial Endomysial Fibrosis. JACC: Clinical Electrophysiology, 10(7), 1326-1340. https://doi.org/10.1016/j.jacep.2024.03.003

Gilbers, M. D., Kawczynski, M. J., Bidar, E., Maesen, B., Isaacs, A., Winters, J., Linz, D., Rienstra, M., van Gelder, I., Maessen, J. G., & Schotten, U. (2024). Clinical Predictors of Device-Detected Atrial Fibrillation During 2.5 Years After Cardiac Surgery: Prospective RACE V Cohort. JACC: Clinical Electrophysiology, 10(5), 941-955. https://doi.org/10.1016/j.jacep.2024.01.013

Christ, A., Maas, S. L., Jin, H., Lu, C., Legein, B., Wijnands, E., Temmerman, L., Otten, J., Isaacs, A., Zenke, M., Stoll, M., Biessen, E. A. L., & van der Vorst, E. P. C. (2024). In situ lipid-loading activates peripheral dendritic cell subsets characterized by cellular ROS accumulation but compromises their capacity to prime naïve T cells. Free Radical Biology and Medicine, 210, 406-415. https://doi.org/10.1016/j.freeradbiomed.2023.11.044