Dr Gert Schaart (G.)

Xia, Y., Caputo, M., Andersson, E., Asiedu, B., Zhang, J., Hou, W., Amrutkar, M., Cansby, E., Gul, N., Gemmink, A., Myers, C., Aghajan, M., Booten, S., Hoy, A. J., Härtlova, A., Lindahl, P., Ståhlberg, A., Schaart, G., Hesselink, M. K. C., ... Mahlapuu, M. (2025). Therapeutic Potential of STE20-Type Kinase STK25 Inhibition for the Prevention and Treatment of Metabolically Induced Hepatocellular Carcinoma. CMGH Cellular and Molecular Gastroenterology and Hepatology, 19(7), Article 101485. https://doi.org/10.1016/j.jcmgh.2025.101485

op den Kamp-bruls, Y. M. H., op den Kamp, Y. J. M., Veeraiah, P., Perez, R. Z., Phielix, E., Havekes, B., Schaart, G., Kornips, E., Berendsen, B. R. B., Virmani, A., Wildberger, J. E., Houtkooper, R. H., Hesselink, M. K. C., Schrauwen, P., & Schrauwen-Hinderling, V. B. (2025). Carnitine supplementation improves insulin sensitivity and skeletal muscle acetylcarnitine formation in patients with type 2 diabetes. Diabetes Obesity & Metabolism, 27(5), 2864-2877. Advance online publication. https://doi.org/10.1111/dom.16298

Sellers, A. J., van Beek, S. M. M., Hashim, D., Baak, R., Pallubinsky, H., Moonen-Kornips, E., Schaart, G., Gemmink, A., Jorgensen, J. A., van de Weijer, T., Kalkhoven, E., Hooiveld, G. J., Kersten, S., Hesselink, M. K. C., Schrauwen, P., Hoeks, J., & Lichtenbelt, W. D. V. M. (2024). Cold acclimation with shivering improves metabolic health in adults with overweight or obesity. Nature Metabolism, 6(12), 2246-2253. Article 1516. https://doi.org/10.1038/s42255-024-01172-y

Chen, S., Wang, Q., Bakker, D., Hu, X., Zhang, L., van der Made, I., Tebbens, A. M., Kovacshazi, C., Giricz, Z., Brenner, G. B., Ferdinandy, P., Schaart, G., Gemmink, A., Hesselink, M. K. C., Rivaud, M. R., Pieper, M. P., Hollmann, M. W., Weber, N. C., Balligand, J.-L., ... Zuurbier, C. J. (2024). Empagliflozin prevents heart failure through inhibition of the NHE1-NO pathway, independent of SGLT2. Basic Research in Cardiology, 119(5), 751-772. https://doi.org/10.1007/s00395-024-01067-9

de Wit-Verheggen, V. H. W., Vanweert, F., Raiko, J., Liénard, V., Schaart, G., Gemmink, A., Nascimento, E. B. M., Hesselink, M. K. C., Wildberger, J. E., Wierts, R., Joris, P. J., Haas, J., Montaigne, D., Staels, B., Phielix, E., Schrauwen, P., Schrauwen-Hinderling, V. B., & van de Weijer, T. (2023). The tissue-specific metabolic effects of the PPARa agonist ciprofibrate in insulin-resistant male individuals: a double-blind, randomized, placebo-controlled crossover study. Obesity, 31(10), 2493-2504. https://doi.org/10.1002/oby.23874

Gemmink, A., Daemen, S., Wefers, J., Hansen, J., van Moorsel, D., Astuti, P., Jorgensen, J. A., Kornips, E., Schaart, G., Hoeks, J., Schrauwen, P., & Hesselink, M. K. C. (2023). Twenty-four hour rhythmicity in mitochondrial network connectivity and mitochondrial respiration; a study in human skeletal muscle biopsies of young lean and older individuals with obesity. Molecular Metabolism, 72(1), Article 101727. https://doi.org/10.1016/j.molmet.2023.101727

de Wit-Verheggen, V. H. W., Schrauwen-Hinderling, V. B., Brouwers, K., Joergensen, J. A., Schaart, G., Gemmink, A., Nascimento, E. B. M., Hesselink, M. K. C., Wildberger, J. E., Segers, P., Montaigne, D., Staels, B., Schrauwen, P., Lindeboom, L., Hoeks, J., & van de Weijer, T. (2023). PCr/ATP ratios and mitochondrial function in the heart. A comparative study in humans. Scientific Reports, 13(1), Article 8346. https://doi.org/10.1038/s41598-023-35041-7

Veelen, A., Andriessen, C., Op den Kamp, Y., Erazo-Tapia, E., de Ligt, M., Mevenkamp, J., Jörgensen, J. A., Moonen-Kornips, E., Schaart, G., Esterline, R., Havekes, B., Oscarsson, J., Schrauwen-Hinderling, V. B., Phielix, E., & Schrauwen, P. (2023). Effects of the sodium-glucose cotransporter 2 inhibitor dapagliflozin on substrate metabolism in prediabetic insulin resistant individuals: A randomized, double-blind crossover trial. Metabolism-Clinical and Experimental, 140(1), Article 155396. https://doi.org/10.1016/j.metabol.2022.155396

van Beek, S. M. M., Bruls, Y. M. H., Vanweert, F., Fealy, C. E., Connell, N. J., Schaart, G., Moonen-Kornips, E., Jorgensen, J. A., Vaz, F. M., Smeets, E. T. H. C., Joris, P. J., Gemmink, A., Houtkooper, R. H., Hesselink, M. K. C., Bengtsson, T., Havekes, B., Schrauwen, P., & Hoeks, J. (2023). Effect of beta 2-agonist treatment on insulin-stimulated peripheral glucose disposal in healthy men in a randomised placebo-controlled trial. Nature Communications, 14(1), Article 173. https://doi.org/10.1038/s41467-023-35798-5

Op den Kamp, Y. J. M., Gemmink, A., de Ligt, M., Dautzenberg, B., Kornips, E., Jorgensen, J. A., Schaart, G., Esterline, R., Pava, D. A., Hoeks, J., Schrauwen-Hinderling, V. B., Kersten, S., Havekes, B., Koves, T. R., Muoio, D. M., Hesselink, M. K. C., Oscarsson, J., Phielix, E., & Schrauwen, P. (2022). Effects of SGLT2 inhibitor dapagliflozin in patients with type 2 diabetes on skeletal muscle cellular metabolism. Molecular Metabolism, 66, Article 101620. https://doi.org/10.1016/j.molmet.2022.101620